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We propose an integrated deep-generative framework, that jointly models complementary information from resting-state functional MRI (rs-fMRI) connectivity and diffusion tensor imaging (DTI) tractography to extract predictive biomarkers of a…

Major depressive disorder (MDD) is a common neuropsychiatric condition whose accurate diagnosis from resting-state functional magnetic resonance imaging (rs-fMRI) remains difficult. Dynamic functional connectivity (DFC) captures…

计算机视觉与模式识别 · 计算机科学 2026-05-26 Muhammad Asif Hasan , Yanming Zhu , Xuefei Yin , Alan Wee-Chung Liew

Building comprehensive brain connectomes has proved of fundamental importance in resting-state fMRI (rs-fMRI) analysis. Based on the foundation of brain network, spatial-temporal-based graph convolutional networks have dramatically improved…

机器学习 · 计算机科学 2023-12-19 Rui Yang , Wenrui Dai , Huajun She , Yiping P. Du , Dapeng Wu , Hongkai Xiong

Resting-state fMRI is commonly used for diagnosing Autism Spectrum Disorder (ASD) by using network-based functional connectivity. It has been shown that ASD is associated with brain regions and their inter-connections. However,…

神经元与认知 · 定量生物学 2022-01-04 Ranjeet Ranjan Jha , Abhishek Bhardwaj , Devin Garg , Arnav Bhavsar , Aditya Nigam

We propose a model for diagnosing Autism spectrum disorder (ASD) using multimodal magnetic resonance imaging (MRI) data. Our approach integrates brain connectivity data from diffusion tensor imaging (DTI) and functional MRI (fMRI),…

神经元与认知 · 定量生物学 2024-10-10 Lu Wei , Yi Huang , Guosheng Yin , Fode Zhang , Manxue Zhang , Bin Liu

Dynamic functional connectivity captures time-varying brain states for better neuropsychiatric diagnosis and spatio-temporal interpretability, i.e., identifying when discriminative disease signatures emerge and where they reside in the…

计算机视觉与模式识别 · 计算机科学 2026-03-11 Guiliang Guo , Guangqi Wen , Lingwen Liu , Ruoxian Song , Peng Cao , Jinzhu Yang , Fei Wang , Xiaoli Liu , Osmar R. Zaiane

Functional Magnetic Resonance Imaging (fMRI) captures the temporal dynamics of neural activity as a function of spatial location in the brain. Thus, fMRI scans are represented as 4-Dimensional (3-space + 1-time) tensors. And it is widely…

计算机视觉与模式识别 · 计算机科学 2020-02-17 Ahmed El-Gazzar , Mirjam Quaak , Leonardo Cerliani , Peter Bloem , Guido van Wingen , Rajat Mani Thomas

Research in machine learning for autism spectrum disorder (ASD) classification bears the promise to improve clinical diagnoses. However, recent studies in clinical imaging have shown the limited generalization of biomarkers across and…

机器学习 · 计算机科学 2022-09-23 Christian Gerloff , Kerstin Konrad , Jana Kruppa , Martin Schulte-Rüther , Vanessa Reindl

Functional connectivity (FC) between regions of the brain can be assessed by the degree of temporal correlation measured with functional neuroimaging modalities. Based on the fact that these connectivities build a network, graph-based…

计算机视觉与模式识别 · 计算机科学 2021-10-22 Byung-Hoon Kim , Jong Chul Ye , Jae-Jin Kim

Autism spectrum disorder(ASD) is a lifelong neurodevelopmental condition that affects social communication and behavior. Investigating functional magnetic resonance imaging (fMRI)-based brain functional connectome can aid in the…

神经元与认知 · 定量生物学 2023-07-21 Anushree Bannadabhavi , Soojin Lee , Wenlong Deng , Xiaoxiao Li

Neuroimaging-based prediction methods for intelligence and cognitive abilities have seen a rapid development in literature. Among different neuroimaging modalities, prediction based on functional connectivity (FC) has shown great promise.…

神经元与认知 · 定量生物学 2023-07-20 Yang Li , Xin Ma , Raj Sunderraman , Shihao Ji , Suprateek Kundu

Increasing the volume of training data can enable the auxiliary diagnostic algorithms for Autism Spectrum Disorder (ASD) to learn more accurate and stable models. However, due to the significant heterogeneity and domain shift in rs-fMRI…

神经元与认知 · 定量生物学 2025-07-11 Yiqian Luo , Qiurong Chen , Fali Li , Peng Xu , Yangsong Zhang

Finding an appropriate representation of dynamic activities in the brain is crucial for many downstream applications. Due to its highly dynamic nature, temporally averaged fMRI (functional magnetic resonance imaging) can only provide a…

机器学习 · 计算机科学 2022-08-18 Sikun Lin , Shuyun Tang , Scott Grafton , Ambuj Singh

Dynamic functional connectivity (dFC) derived from resting-state functional magnetic resonance imaging (fMRI) has been extensively utilized in brain science research. The sliding window correlation (SWC) method is a widely used approach for…

神经元与认知 · 定量生物学 2026-03-27 Jinlong Hu , Jiatong Huang , Zijian Cai

We present an approach to model time series data from resting state fMRI for autism spectrum disorder (ASD) severity classification. We propose to adopt kernel machines and employ graph kernels that define a kernel dot product between two…

机器学习 · 统计学 2016-12-04 Rushil Anirudh , Jayaraman J. Thiagarajan , Irene Kim , Wolfgang Polonik

Using deep learning models to recognize functional brain networks (FBNs) in functional magnetic resonance imaging (fMRI) has been attracting increasing interest recently. However, most existing work focuses on detecting static FBNs from…

计算机视觉与模式识别 · 计算机科学 2022-06-01 Yiheng Liu , Enjie Ge , Mengshen He , Zhengliang Liu , Shijie Zhao , Xintao Hu , Dajiang Zhu , Tianming Liu , Bao Ge

Brain functional connectivity (FC) reveals biomarkers for identification of various neuropsychiatric disorders. Recent application of deep neural networks (DNNs) to connectome-based classification mostly relies on traditional convolutional…

神经元与认知 · 定量生物学 2024-01-31 Fuad Noman , Chee-Ming Ting , Hakmook Kang , Raphael C. -W. Phan , Brian D. Boyd , Warren D. Taylor , Hernando Ombao

Asynchronous Time Series is a multivariate time series where all the channels are observed asynchronously-independently, making the time series extremely sparse when aligning them. We often observe this effect in applications with complex…

机器学习 · 计算机科学 2022-08-25 Vijaya Krishna Yalavarthi , Johannes Burchert , Lars Schmidt-Thieme

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and behavioral patterns. Eye movement data offers a non-invasive diagnostic tool for ASD detection, as it is inherently…

机器学习 · 计算机科学 2026-01-12 Zhanpei Huang , Taochen chen , Fangqing Gu , Yiqun Zhang

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by complex physiological processes. Previous research has predominantly focused on static cerebral interactions, often neglecting the brain's dynamic nature and…

机器学习 · 计算机科学 2024-09-11 Peng Wang , Xin Wen , Ruochen Cao , Chengxin Gao , Yanrong Hao , Rui Cao