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Single particle imaging (SPI) at X-ray free electron lasers (XFELs) is particularly well suited to determine the 3D structure of particles in their native environment. For a successful reconstruction, diffraction patterns originating from a…

数据分析、统计与概率 · 物理学 2021-12-17 Dameli Assalauova , Alexandr Ignatenko , Fabian Isensee , Sergey Bobkov , Darya Trofimova , Ivan A. Vartanyants

Single particle imaging (SPI) at X-ray free electron lasers (XFELs) is a technique to determine the 3D structure of nanoscale objects like biomolecules from a large number of diffraction patterns of copies of these objects in random…

图像与视频处理 · 电气工程与系统科学 2022-10-20 Abhishek Mall , Kartik Ayyer

The development of X-ray Free Electron Lasers (XFELs) has opened numerous opportunities to probe atomic structure and ultrafast dynamics of various materials. Single Particle Imaging (SPI) with XFELs enables the investigation of biological…

计算机视觉与模式识别 · 计算机科学 2023-11-29 Zhantao Chen , Cong Wang , Mingye Gao , Chun Hong Yoon , Jana B. Thayer , Joshua J. Turner

X-ray free-electron lasers (XFELs) offer unique capabilities for measuring the structure and dynamics of biomolecules, helping us understand the basic building blocks of life. Notably, high-repetition-rate XFELs enable single particle…

计算机视觉与模式识别 · 计算机科学 2023-12-25 Jay Shenoy , Axel Levy , Frédéric Poitevin , Gordon Wetzstein

Current Flash X-ray single-particle diffraction Imaging (FXI) experiments, which operate on modern X-ray Free Electron Lasers (XFELs), can record millions of interpretable diffraction patterns from individual biomolecules per day. Due to…

计算机视觉与模式识别 · 计算机科学 2019-02-20 Jing Liu , Gijs van der Schot , Stefan Engblom

Single particle imaging (SPI) is a promising method for native structure determination which has undergone a fast progress with the development of X-ray Free-Electron Lasers. Large amounts of data are collected during SPI experiments,…

图像与视频处理 · 电气工程与系统科学 2021-04-23 Alexandr Ignatenko , Dameli Assalauova , Sergey A. Bobkov , Luca Gelisio , Anton B. Teslyuk , Viacheslav A. Ilyin , Ivan A. Vartanyants

Pattern recognition and image classification are essential tasks in machine vision. Autonomous vehicles, for example, require being able to collect the complex information contained in a changing environment and classify it in real time.…

Spectral-spatial classification of hyperspectral images has been the subject of many studies in recent years. In the presence of only very few labeled pixels, this task becomes challenging. In this paper we address the following two…

计算机视觉与模式识别 · 计算机科学 2018-07-24 Jacopo Acquarelli , Elena Marchiori , Lutgarde M. C. Buydens , Thanh Tran , Twan van Laarhoven

The Linac Coherent Light Source (LCLS) is an X- ray free electron laser (XFEL) facility enabling the study of the structure and dynamics of single macromolecules. A major upgrade will bring the repetition rate of the X-ray source from 120…

X-ray single particle imaging (SPI) has offered the potential to visualize structures of biomolecules at near-atomic resolution. However, state-of-the-art structures at X-ray free electron lasers (XFELs) are limited to moderate resolution,…

光学 · 物理学 2025-08-12 Abhishek Mall , Zhou Shen , Kartik Ayyer

Elastic light scattering has been extensively used to study samples showing a non uniform refraction index on lengthscales from a fraction of a micrometer to a fraction of a millimeter. Typically, a wide laser beam is sent through the…

光学 · 物理学 2009-07-21 Doriano Brogioli

Single-shot wide-angle diffraction imaging is a widely used method to investigate the structure of non-crystallizing objects such as nanoclusters, large proteins or even viruses. Its main advantage is that information about the…

数据分析、统计与概率 · 物理学 2021-06-02 Thomas Stielow , Stefan Scheel

We propose an encryption-decryption framework for validating diffraction intensity volumes reconstructed using single-particle imaging (SPI) with x-ray free-electron lasers (XFELs) when the ground truth volume is absent. This framework…

数据分析、统计与概率 · 物理学 2020-08-03 Zhou Shen , Colin Zhi Wei Teo , Kartik Ayyer , N. Duane Loh

X-ray single particle imaging involves the measurement of a large number of noisy diffraction patterns of isolated objects in random orientations. The missing information about these patterns is then computationally recovered in order to…

图像与视频处理 · 电气工程与系统科学 2020-05-25 Kartik Ayyer

In this paper, the advancements in structured light beams recognition using speckle-based convolutional neural networks (CNNs) have been presented. Speckle fields, generated by the interference of multiple wavefronts diffracted and…

光学 · 物理学 2023-11-02 Venugopal Raskatla , Purnesh Singh Badavath , Vijay Kumar

Label free tracking of small bio-particles such as proteins or viruses is of great utility in the study of biological processes, however such experiments are frequently hindered by weak signal strengths and a susceptibility to scattering…

光学 · 物理学 2021-08-03 Joel Berk , Carl Paterson , Matthew R. Foreman

Single-shot diffraction imaging of isolated nanosized particles has seen remarkable success in recent years, yielding in-situ measurements with ultra-high spatial and temporal resolution. The progress of high-repetition-rate sources for…

原子与分子团簇 · 物理学 2022-08-26 Julian Zimmermann , Fabien Beguet , Daniel Guthruf , Bruno Langbehn , Daniela Rupp

X-ray phase-contrast imaging offers enhanced sensitivity for weakly-attenuating materials, such as breast and brain tissue, but has yet to be widely implemented clinically due to high coherence requirements and expensive x-ray optics.…

医学物理 · 物理学 2023-05-04 Serena Qinyun Z. Shi , Nadav Shapira , Peter B. Noël , Sebastian Meyer

X-ray Photoelectron Spectroscopy (XPS) is a crucial technique for material surface analysis, yet interpreting its spectra is often challenging for both human analysts and automated methods due to the prevalence of variable spectral shifts…

材料科学 · 物理学 2026-03-06 Issa Saddiq , Yuxin Fan , Robert G. Palgrave , Mark A. Isaacs , David Morgan , Keith T. Butler
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