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Medical image data is less accessible than in other domains due to privacy and regulatory constraints. In addition, labeling requires costly, time-intensive manual image annotation by clinical experts. To overcome these challenges,…

图像与视频处理 · 电气工程与系统科学 2025-07-11 Fangyijie Wang , Kevin Whelan , Félix Balado , Kathleen M. Curran , Guénolé Silvestre

Semantic medical image segmentation using deep learning has recently achieved high accuracy, making it appealing to clinical problems such as radiation therapy. However, the lack of high-quality semantically labelled data remains a…

图像与视频处理 · 电气工程与系统科学 2023-03-13 Wei Dai , Siyu Liu , Craig B. Engstrom , Shekhar S. Chandra

Diffusion models have enabled remarkably high-quality medical image generation, yet it is challenging to enforce anatomical constraints in generated images. To this end, we propose a diffusion model-based method that supports…

图像与视频处理 · 电气工程与系统科学 2024-06-21 Nicholas Konz , Yuwen Chen , Haoyu Dong , Maciej A. Mazurowski

The development of generative models in the past decade has allowed for hyperrealistic data synthesis. While potentially beneficial, this synthetic data generation process has been relatively underexplored in cancer histopathology. One…

图像与视频处理 · 电气工程与系统科学 2024-12-10 Aakash Madhav Rao , Debayan Gupta

Analyzing medical data to find abnormalities is a time-consuming and costly task, particularly for rare abnormalities, requiring tremendous efforts from medical experts. Artificial intelligence has become a popular tool for the automatic…

Histopathological analysis is the present gold standard for precancerous lesion diagnosis. The goal of automated histopathological classification from digital images requires supervised training, which requires a large number of expert…

图像与视频处理 · 电气工程与系统科学 2021-11-15 Yuan Xue , Jiarong Ye , Qianying Zhou , Rodney Long , Sameer Antani , Zhiyun Xue , Carl Cornwell , Richard Zaino , Keith Cheng , Xiaolei Huang

Deep learning techniques have become widely utilized in histopathology image classification due to their superior performance. However, this success heavily relies on the availability of substantial labeled data, which necessitates…

图像与视频处理 · 电气工程与系统科学 2024-10-15 Meng Li , Chaoyi Li , Can Peng , Brian C. Lovell

In medical image diagnosis, pathology image analysis using semantic segmentation becomes important for efficient screening as a field of digital pathology. The spatial augmentation is ordinary used for semantic segmentation. Tumor images…

机器学习 · 计算机科学 2021-03-04 Takato Yasuno

Synthetic data generation in histopathology faces unique challenges: preserving tissue heterogeneity, capturing subtle morphological features, and scaling to unannotated datasets. We present a latent diffusion model that generates realistic…

计算机视觉与模式识别 · 计算机科学 2025-10-03 Saghir Alfasly , Wataru Uegami , MD Enamul Hoq , Ghazal Alabtah , H. R. Tizhoosh

Generative modelling and synthetic data can be a surrogate for real medical imaging datasets, whose scarcity and difficulty to share can be a nuisance when delivering accurate deep learning models for healthcare applications. In recent…

图像与视频处理 · 电气工程与系统科学 2024-02-27 Virginia Fernandez , Walter Hugo Lopez Pinaya , Pedro Borges , Mark S. Graham , Tom Vercauteren , M. Jorge Cardoso

The use of synthetic images in medical imaging Artificial Intelligence (AI) solutions has been shown to be beneficial in addressing the limited availability of diverse, unbiased, and representative data. Despite the extensive use of…

计算机视觉与模式识别 · 计算机科学 2024-12-10 Elay Dahan , Hedda Cohen Indelman , Angeles M. Perez-Agosto , Carmit Shiran , Gopal Avinash , Doron Shaked , Nati Daniel

Tumor segmentation plays a critical role in histopathology, but it requires costly, fine-grained image-mask pairs annotated by pathologists. Thus, synthesizing histopathology data to expand the dataset is highly desirable. Previous works…

计算机视觉与模式识别 · 计算机科学 2025-03-07 Hong Liu , Haosen Yang , Evi M. C. Huijben , Mark Schuiveling , Ruisheng Su , Josien P. W. Pluim , Mitko Veta

This paper presents a new regularization method to train a fully convolutional network for semantic tissue segmentation in histopathological images. This method relies on the benefit of unsupervised learning, in the form of image…

计算机视觉与模式识别 · 计算机科学 2020-11-26 C. T. Sari , C. Sokmensuer , C. Gunduz-Demir

Existing 3D-aware facial generation methods face a dilemma in quality versus editability: they either generate editable results in low resolution or high-quality ones with no editing flexibility. In this work, we propose a new approach that…

计算机视觉与模式识别 · 计算机科学 2022-06-01 Jingxiang Sun , Xuan Wang , Yichun Shi , Lizhen Wang , Jue Wang , Yebin Liu

Generative models capable of capturing nuanced clinical features in medical images hold great promise for facilitating clinical data sharing, enhancing rare disease datasets, and efficiently synthesizing annotated medical images at scale.…

图像与视频处理 · 电气工程与系统科学 2023-06-23 Shenghuan Sun , Gregory M. Goldgof , Atul Butte , Ahmed M. Alaa

In computational pathology, understanding and generation have evolved along disparate paths: advanced understanding models already exhibit diagnostic-level competence, whereas generative models largely simulate pixels. Progress remains…

计算机视觉与模式识别 · 计算机科学 2026-02-27 Minghao Han , Yichen Liu , Yizhou Liu , Zizhi Chen , Jingqun Tang , Xuecheng Wu , Dingkang Yang , Lihua Zhang

Deep learning models show promise in digital pathology, but their opaque decision-making processes limit trust and clinical adoption. To address this challenge, we present HIPPO, an explainable AI method for analyzing weakly-supervised…

组织与器官 · 定量生物学 2025-12-10 Jakub R. Kaczmarzyk , Chanwoo Kim , Soham Gadgil , Deepika Savant , Zhen Zhao , Joel H. Saltz , Su-In Lee , Peter K. Koo

In this paper, we address the task of semantic-guided image generation. One challenge common to most existing image-level generation methods is the difficulty in generating small objects and detailed local textures. To address this, in this…

计算机视觉与模式识别 · 计算机科学 2022-03-02 Hao Tang , Ling Shao , Philip H. S. Torr , Nicu Sebe

We present PathoSyn, a unified generative framework for Magnetic Resonance Imaging (MRI) image synthesis that reformulates imaging-pathology as a disentangled additive deviation on a stable anatomical manifold. Current generative models…

计算机视觉与模式识别 · 计算机科学 2026-01-14 Jian Wang , Sixing Rong , Jiarui Xing , Yuling Xu , Weide Liu

Pseudo healthy synthesis, i.e. the creation of a subject-specific `healthy' image from a pathological one, could be helpful in tasks such as anomaly detection, understanding changes induced by pathology and disease or even as data…

计算机视觉与模式识别 · 计算机科学 2019-01-23 Tian Xia , Agisilaos Chartsias , Sotirios A. Tsaftaris