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Healthcare requires AI that is predictive, reliable, and data-efficient. However, recent generative models lack physical foundation and temporal reasoning required for clinical decision support. As scaling language models show diminishing…

机器学习 · 计算机科学 2025-11-21 Mohammad Areeb Qazi , Maryam Nadeem , Mohammad Yaqub

The integration of Artificial Intelligence (AI), especially Large Language Models (LLMs), into the clinical diagnosis process offers significant potential to improve the efficiency and accessibility of medical care. While LLMs have shown…

计算与语言 · 计算机科学 2024-10-15 Mingyu Derek Ma , Chenchen Ye , Yu Yan , Xiaoxuan Wang , Peipei Ping , Timothy S Chang , Wei Wang

Artificial intelligence (AI) systems increasingly match or surpass human experts in biomedical signal interpretation. However, their effective integration into clinical practice requires more than high predictive accuracy. Clinicians must…

机器学习 · 计算机科学 2025-10-27 Stefan Kraft , Andreas Theissler , Vera Wienhausen-Wilke , Gjergji Kasneci , Hendrik Lensch

Large language models (LLMs) exhibit remarkable capabilities, yet their reasoning remains opaque, raising safety and trust concerns. Attribution methods, which assign credit to input features, have proven effective for explaining the…

人工智能 · 计算机科学 2025-12-18 Chase Walker , Rickard Ewetz

Contextual optimization, also known as predict-then-optimize or prescriptive analytics, considers an optimization problem with the presence of covariates (context or side information). The goal is to learn a prediction model (from the…

最优化与控制 · 数学 2024-05-13 Chunlin Sun , Linyu Liu , Xiaocheng Li

Clinical diagnosis is a complex reasoning process in which clinicians gather evidence, form hypotheses, and test them against alternative explanations. In medical training, this reasoning is explicitly developed through counterfactual…

计算与语言 · 计算机科学 2026-04-24 Zhiwen You , Xi Chen , Aniket Vashishtha , Simo Du , Gabriel Erion-Barner , Hongyuan Mei , Hao Peng , Yue Guo

Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that…

We introduce a multi-turn benchmark for evaluating personalised alignment in LLM-based AI assistants, focusing on their ability to handle user-provided safety-critical contexts. Our assessment of ten leading models across five scenarios…

人机交互 · 计算机科学 2025-01-31 Lize Alberts , Benjamin Ellis , Andrei Lupu , Jakob Foerster

Deep learning (DL) based predictive models from electronic health records (EHR) deliver impressive performance in many clinical tasks. Large training cohorts, however, are often required to achieve high accuracy, hindering the adoption of…

计算与语言 · 计算机科学 2020-05-27 Laila Rasmy , Yang Xiang , Ziqian Xie , Cui Tao , Degui Zhi

Objective. Type 2 diabetes mellitus (T2DM) is a highly prevalent non-communicable chronic disease that substantially reduces life expectancy. Accurate estimation of all-cause mortality risk in T2DM patients is crucial for personalizing and…

Large language models (LLMs) have shown promise in translating model-based explanations into human-readable narratives. This study evaluates whether LLMs can serve as post-hoc explainability interfaces for credit risk models, focusing on…

风险管理 · 定量金融 2026-05-19 Wenxi Geng , Dingyuan Liu , Liya Li , Yiqing Wang

Machine Learning (ML) algorithms are vital for supporting clinical decision-making in biomedical informatics. However, their predictive performance can vary across demographic groups, often due to the underrepresentation of historically…

机器学习 · 计算机科学 2025-03-04 Ioannis Bilionis , Ricardo C. Berrios , Luis Fernandez-Luque , Carlos Castillo

Healthcare systems around the world are grappling with issues like inefficient diagnostics, rising costs, and limited access to specialists. These problems often lead to delays in treatment and poor health outcomes. Most current AI and deep…

人工智能 · 计算机科学 2025-12-22 Maliha Tabassum , M Shamim Kaiser

Improving the performance and natural language explanations of deep learning algorithms is a priority for adoption by humans in the real world. In several domains, such as healthcare, such technology has significant potential to reduce the…

人工智能 · 计算机科学 2022-04-28 Kaushik Roy , Manas Gaur , Qi Zhang , Amit Sheth

Advances in AI have introduced several strong models in computational pathology to usher it into the era of multi-modal diagnosis, analysis, and interpretation. However, the current pathology-specific visual language models still lack…

Large language models (LLMs) are increasingly being used in a zero-shot fashion to assess mental health conditions, yet we have limited knowledge on what factors affect their accuracy. In this study, we utilize a clinical dataset of natural…

AI recommender systems are sought for decision support by providing suggestions to operators responsible for making final decisions. However, these systems are typically considered black boxes, and are often presented without any context or…

人机交互 · 计算机科学 2023-10-18 Divya K. Srivastava , J. Mason Lilly , Karen M. Feigh

Large language model-powered chatbots have transformed how people seek information, especially in high-stakes contexts like mental health. Despite their support capabilities, safe detection and response to crises such as suicidal ideation…

Providing high quality explanations for AI predictions based on machine learning is a challenging and complex task. To work well it requires, among other factors: selecting a proper level of generality/specificity of the explanation;…

Autonomous vehicles often make complex decisions via machine learning-based predictive models applied to collected sensor data. While this combination of methods provides a foundation for real-time actions, self-driving behavior primarily…

机器人学 · 计算机科学 2024-04-12 Shahin Atakishiyev , Mohammad Salameh , Randy Goebel
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