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Multi-Instance Learning (MIL) has shown impressive performance for histopathology whole slide image (WSI) analysis using bags or pseudo-bags. It involves instance sampling, feature representation, and decision-making. However, existing…

计算机视觉与模式识别 · 计算机科学 2024-03-14 Tingting Zheng , Kui Jiang , Hongxun Yao

The fine-grained annotations in whole slide images (WSIs) show the boundaries of various pathological regions. However, generating such detailed annotation is often costly, whereas the coarse annotations are relatively simpler to produce.…

计算机视觉与模式识别 · 计算机科学 2025-03-26 Bingjian Yao , Weiping Lin , Yan He , Zheng Wang , Liangsheng Wang

Explainable Artificial Intelligence (XAI) is an emerging research field bringing transparency to highly complex and opaque machine learning (ML) models. Despite the development of a multitude of methods to explain the decisions of black-box…

机器学习 · 计算机科学 2022-03-16 Leander Weber , Sebastian Lapuschkin , Alexander Binder , Wojciech Samek

Explainable AI (XAI) promises to provide insight into machine learning models' decision processes, where one goal is to identify failures such as shortcut learning. This promise relies on the field's assumption that input features marked as…

机器学习 · 计算机科学 2026-02-19 Benedict Clark , Marta Oliveira , Rick Wilming , Stefan Haufe

Whole Slide Images (WSIs) are critical for various clinical applications, including histopathological analysis. However, current deep learning approaches in this field predominantly focus on individual tumor types, limiting model…

图像与视频处理 · 电气工程与系统科学 2024-09-18 Sharon Peled , Yosef E. Maruvka , Moti Freiman

Multi-instance learning (MIL) is widely used in the computer-aided interpretation of pathological Whole Slide Images (WSIs) to solve the lack of pixel-wise or patch-wise annotations. Often, this approach directly applies "natural image…

Histopathology Whole Slide Image (WSI) analysis serves as the gold standard for clinical cancer diagnosis in the daily routines of doctors. To develop computer-aided diagnosis model for WSIs, previous methods typically employ Multi-Instance…

计算机视觉与模式识别 · 计算机科学 2024-10-21 Honglin Li , Yunlong Zhang , Pingyi Chen , Zhongyi Shui , Chenglu Zhu , Lin Yang

Text classification aims to effectively categorize documents into pre-defined categories. Traditional methods for text classification often rely on large amounts of manually annotated training data, making the process time-consuming and…

计算与语言 · 计算机科学 2023-11-02 Daniel Hajialigol , Hanwen Liu , Xuan Wang

Explainable artificial intelligence (XAI) plays an indispensable role in demystifying the decision-making processes of AI, especially within the healthcare industry. Clinicians rely heavily on detailed reasoning when making a diagnosis,…

计算机视觉与模式识别 · 计算机科学 2024-03-26 Anna Stubbin , Thompson Chyrikov , Jim Zhao , Christina Chajo

Computational pathology holds substantial promise for improving diagnosis and guiding treatment decisions. Recent pathology foundation models enable the extraction of rich patch-level representations from large-scale whole-slide images…

计算机视觉与模式识别 · 计算机科学 2025-11-20 Xiangde Luo , Jinxi Xiang , Yuanfeng Ji , Ruijiang Li

Automated generation of diagnostic pathology reports directly from whole slide images (WSIs) is an emerging direction in computational pathology. Translating high-resolution tissue patterns into clinically coherent text remains difficult…

计算机视觉与模式识别 · 计算机科学 2025-12-16 Noorul Wahab , Nasir Rajpoot

This project aims to break down large pathology images into small tiles and then cluster those tiles into distinct groups without the knowledge of true labels, our analysis shows how difficult certain aspects of clustering tumorous and…

图像与视频处理 · 电气工程与系统科学 2020-12-29 Mostafa Ibrahim , Kevin Bryson

Malignant lymphoma subtype classification directly impacts treatment strategies and patient outcomes, necessitating classification models that achieve both high accuracy and sufficient explainability. This study proposes a novel explainable…

计算机视觉与模式识别 · 计算机科学 2025-03-04 Daiki Nishiyama , Hiroaki Miyoshi , Noriaki Hashimoto , Koichi Ohshima , Hidekata Hontani , Ichiro Takeuchi , Jun Sakuma

Artificial Intelligence techniques can be used to classify a patient's physical activities and predict vital signs for remote patient monitoring. Regression analysis based on non-linear models like deep learning models has limited…

人工智能 · 计算机科学 2024-10-28 Thanveer Shaik , Xiaohui Tao , Haoran Xie , Lin Li , Juan D. Velasquez , Niall Higgins

Quality assurance is a critical but underexplored area in digital pathology, where even minor artifacts can have significant effects. Artifacts have been shown to negatively impact the performance of AI diagnostic models. In current…

图像与视频处理 · 电气工程与系统科学 2025-06-13 Meredith VandeHaar , M. Clinch , I. Yilmaz , M. A. Rahman , Y. Xiao , F. Dogany , H. M. Alazab , A. Nassar , Z. Akkus , B. Dangott

Due to the large size and lack of fine-grained annotation, Whole Slide Images (WSIs) analysis is commonly approached as a Multiple Instance Learning (MIL) problem. However, previous studies only learn from training data, posing a stark…

计算机视觉与模式识别 · 计算机科学 2024-11-28 Weiqin Zhao , Ziyu Guo , Yinshuang Fan , Yuming Jiang , Maximus Yeung , Lequan Yu

Whole slide image (WSI) analysis in digital pathology presents unique challenges due to the gigapixel resolution of WSIs and the scarcity of dense supervision signals. While Multiple Instance Learning (MIL) is a natural fit for slide-level…

计算机视觉与模式识别 · 计算机科学 2025-08-21 Sofiène Boutaj , Marin Scalbert , Pierre Marza , Florent Couzinie-Devy , Maria Vakalopoulou , Stergios Christodoulidis

Histopathological images contain abundant phenotypic information and pathological patterns, which are the gold standards for disease diagnosis and essential for the prediction of patient prognosis and treatment outcome. In recent years,…

计算机视觉与模式识别 · 计算机科学 2022-10-26 Linhao Qu , Siyu Liu , Xiaoyu Liu , Manning Wang , Zhijian Song

Deep learning has shown strong potential in cancer classification from whole-slide images (WSIs), but the need for extensive expert annotations often limits its success. Annotation-free approaches, such as multiple instance learning (MIL)…

计算机视觉与模式识别 · 计算机科学 2026-03-12 Willmer Rafell Quinones Robles , Sakonporn Noree , Jongwoo Kim , Young Sin Ko , Bryan Wong , Mun Yong Yi

Multi-instance learning (MIL) is an effective paradigm for whole-slide pathological images (WSIs) classification to handle the gigapixel resolution and slide-level label. Prevailing MIL methods primarily focus on improving the feature…

计算机视觉与模式识别 · 计算机科学 2023-03-14 Tiancheng Lin , Zhimiao Yu , Hongyu Hu , Yi Xu , Chang Wen Chen