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Over the last decade, a large variety of clustering algorithms have been developed to detect coregulatory relationships among genes from microarray gene expression data. Model based clustering approaches have emerged as statistically well…

定量方法 · 定量生物学 2008-01-15 Anagha Joshi , Yves Van de Peer , Tom Michoel

Traditional clustering methods are limited when dealing with huge and heterogeneous groups of gene expression data, which motivates the development of bi-clustering methods. Bi-clustering methods are used to mine bi-clusters whose subsets…

计算机视觉与模式识别 · 计算机科学 2020-05-13 Kaijie Xu , Witold Pedrycz , Zhiwu Li , Yinghui Quan , Weike Nie

With the rapid advances of microarray technologies, large amounts of high-dimensional gene expression data are being generated, which poses significant computational challenges. A first step towards addressing this challenge is the use of…

计算机视觉与模式识别 · 计算机科学 2013-02-14 P. K. Nizar Banu , H. Hannah Inbarani

Machine learning (ML) approaches have been used to develop highly accurate and efficient applications in many fields including bio-medical science. However, even with advanced ML techniques, cancer classification using gene expression data…

基因组学 · 定量生物学 2023-05-10 Mahmood Khalsan , Mu Mu , Eman Salih Al-Shamery , Lee Machado , Suraj Ajit , Michael Opoku Agyeman

Clustering is one of the widely used data mining techniques for medical diagnosis. Clustering can be considered as the most important unsupervised learning technique. Most of the clustering methods group data based on distance and few…

机器学习 · 计算机科学 2012-12-24 K. Dhanalakshmi , H. Hannah Inbarani

In most gene expression data, the number of training samples is very small compared to the large number of genes involved in the experiments. However, among the large amount of genes, only a small fraction is effective for performing a…

机器学习 · 计算机科学 2013-06-07 T. Chandrasekhar , K. Thangavel , E. N. Sathishkumar

The Fuzzy Gene Filter (FGF) is an optimised Fuzzy Inference System designed to rank genes in order of differential expression, based on expression data generated in a microarray experiment. This paper examines the effectiveness of the FGF…

机器学习 · 计算机科学 2011-08-24 Meir Perez , Tshilidzi Marwala

Biclustering is an unsupervised data mining technique that aims to unveil patterns (biclusters) from gene expression data matrices. In the framework of this thesis, we propose new biclustering algorithms for microarray data. The latter is…

机器学习 · 计算机科学 2018-11-26 Amina Houari

We present a novel coupled two-way clustering approach to gene microarray data analysis. The main idea is to identify subsets of the genes and samples, such that when one of these is used to cluster the other, stable and significant…

生物物理 · 物理学 2009-11-06 G. Getz , E. Levine , E. Domany

In statistics and machine learning, feature selection is the process of picking a subset of relevant attributes for utilizing in a predictive model. Recently, rough set-based feature selection techniques, that employ feature dependency to…

机器学习 · 计算机科学 2020-03-30 Seyedeh Faezeh Farahbakhshian , Milad Taleby Ahvanooey

Clustering of gene expression time series gives insight into which genes may be coregulated, allowing us to discern the activity of pathways in a given microarray experiment. Of particular interest is how a given group of genes varies with…

定量方法 · 定量生物学 2018-02-13 Muhammad Arifur Rahman , Paul R. Heath , Neil D. Lawrence

The work presents an extension of the fuzzy approach to 2-D shape recognition [1] through refinement of initial or coarse classification decisions under a two pass approach. In this approach, an unknown pattern is classified by refining…

计算机视觉与模式识别 · 计算机科学 2014-10-16 Subhadip Basu , Mahantapas Kundu , Mita Nasipuri , Dipak Kumar Basu

In the biclustering problem, we seek to simultaneously group observations and features. While biclustering has applications in a wide array of domains, ranging from text mining to collaborative filtering, the problem of identifying…

统计方法学 · 统计学 2018-06-07 Eric C. Chi , Genevera I. Allen , Richard G. Baraniuk

Motivation: Modelling methods that find structure in data are necessary with the current large volumes of genomic data, and there have been various efforts to find subsets of genes exhibiting consistent patterns over subsets of treatments.…

机器学习 · 计算机科学 2016-09-15 Kerstin Bunte , Eemeli Leppäaho , Inka Saarinen , Samuel Kaski

Microarray data analysis is one of the major area of research in the field computational biology. Numerous techniques like clustering, biclustering are often applied to microarray data to extract meaningful outcomes which play key roles in…

神经与进化计算 · 计算机科学 2019-09-04 Shubhankar Mohapatra , Moumita Sarkar , Anjali Mohapatra , Bhawani Sankar Biswal

Bi-clustering is a useful approach in analyzing biological data when observations come from heterogeneous groups and have a large number of features. We outline a general Bayesian approach in tackling bi-clustering problems in moderate to…

应用统计 · 统计学 2021-02-11 Han Yan , Jiexing Wu , Yang Li , Jun S. Liu

Disease subtype identification (clustering) is an important problem in biomedical research. Gene expression profiles are commonly utilized to infer disease subtypes, which often lead to biologically meaningful insights into disease. Despite…

统计方法学 · 统计学 2016-09-27 Jiehuan Sun , Joshua L. Warren , Hongyu Zhao

This paper proposes an efficient technique for partitioning large biometric database during identification. In this technique feature vector which comprises of global and local descriptors extracted from offline signature are used by fuzzy…

计算机视觉与模式识别 · 计算机科学 2010-02-03 Hunny Mehrotra , Dakshina Ranjan Kisku , V. Bhawani Radhika , Banshidhar Majhi , Phalguni Gupta

Gene expression-based heterogeneity analysis has been extensively conducted. In recent studies, it has been shown that network-based analysis, which takes a system perspective and accommodates the interconnections among genes, can be more…

统计方法学 · 统计学 2023-08-09 Rong Li , Qingzhao Zhang , Shuangge Ma

Feature selection is a vital technique in machine learning, as it can reduce computational complexity, improve model performance, and mitigate the risk of overfitting. However, the increasing complexity and dimensionality of datasets pose…

机器学习 · 计算机科学 2024-07-24 Yuepeng Chen , Weiping Ding , Hengrong Ju , Jiashuang Huang , Tao Yin
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