相关论文: On Pre-trained Language Models for Antibody

Pre-trained language models such as ClinicalBERT have achieved impressive results on tasks such as medical Natural Language Inference. At first glance, this may suggest that these models are able to perform medical reasoning tasks, such as…

Successful methods for unsupervised neural machine translation (UNMT) employ crosslingual pretraining via self-supervision, often in the form of a masked language modeling or a sequence generation task, which requires the model to align the…

Recently, the emergence of pre-trained models (PTMs) has brought natural language processing (NLP) to a new era. In this survey, we provide a comprehensive review of PTMs for NLP. We first briefly introduce language representation learning…

Recent advancements in deep learning, particularly large language models (LLMs), made a significant impact on how researchers study microbiome and metagenomics data. Microbial protein and genomic sequences, like natural languages, form a…

Pre-trained Language Models (PLMs) have been widely used in various natural language processing (NLP) tasks, owing to their powerful text representations trained on large-scale corpora. In this paper, we propose a new PLM called PERT for…

The recent success of question answering systems is largely attributed to pre-trained language models. However, as language models are mostly pre-trained on general domain corpora such as Wikipedia, they often have difficulty in…

Large pre-trained language models (PLMs) have demonstrated strong performance on natural language understanding (NLU) tasks through fine-tuning. However, fine-tuned models still suffer from overconfident predictions, especially in…

At the intersection of the rapidly growing biological data landscape and advancements in Natural Language Processing (NLP), protein language models (PLMs) have emerged as a transformative force in modern research. These models have achieved…

Understanding the relationship between antibody sequence, structure and function is essential for the design of antibody-based therapeutics and research tools. Recently, machine learning (ML) models mostly based on the application of large…

While pre-trained language models (LMs) have brought great improvements in many NLP tasks, there is increasing attention to explore capabilities of LMs and interpret their predictions. However, existing works usually focus only on a certain…

Self-supervised protein language models have proved their effectiveness in learning the proteins representations. With the increasing computational power, current protein language models pre-trained with millions of diverse sequences can…

Recently, language models have demonstrated strong performance on various natural language understanding tasks. Language models trained on large human-generated corpus encode not only a significant amount of human knowledge, but also the…

Self-supervised pretraining on speech data has achieved a lot of progress. High-fidelity representation of the speech signal is learned from a lot of untranscribed data and shows promising performance. Recently, there are several works…

Backdoor attacks pose a critical threat by embedding hidden triggers into inputs, causing models to misclassify them into target labels. While extensive research has focused on mitigating these attacks in object recognition models through…

Pre-trained Language Model (PLM) has become a representative foundation model in the natural language processing field. Most PLMs are trained with linguistic-agnostic pre-training tasks on the surface form of the text, such as the masked…

The parallels between protein sequences and natural language in their sequential structures have inspired the application of large language models (LLMs) to protein understanding. Despite the success of LLMs in NLP, their effectiveness in…

Pre-trained language models have achieved promising performance on general benchmarks, but underperform when migrated to a specific domain. Recent works perform pre-training from scratch or continual pre-training on domain corpora. However,…

Language model benchmarks are pervasive and computationally-efficient proxies for real-world performance. However, many recent works find that benchmarks often fail to predict real utility. Towards bridging this gap, we introduce benchmark…

The adaptive immune response, largely mediated by B-cell receptors (BCRs), plays a crucial role for effective pathogen neutralization due to its diversity and antigen specificity. Designing BCRs de novo, or from scratch, has been…

Language is essentially a complex, intricate system of human expressions governed by grammatical rules. It poses a significant challenge to develop capable AI algorithms for comprehending and grasping a language. As a major approach,…