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We study the problem of detecting adverse drug events in electronic healthcare records. The challenge in this work is to aggregate heterogeneous data types involving diagnosis codes, drug codes, as well as lab measurements. An earlier…

机器学习 · 计算机科学 2019-07-16 Maria Bampa , Panagiotis Papapetrou

Event detection (ED), a key subtask of information extraction, aims to recognize instances of specific event types in text. Previous studies on the task have verified the effectiveness of integrating syntactic dependency into graph…

计算与语言 · 计算机科学 2020-09-30 Shiyao Cui , Bowen Yu , Tingwen Liu , Zhenyu Zhang , Xuebin Wang , Jinqiao Shi

Post--marketing pharmacovigilance is essential for identifying adverse drug reactions (ADRs) that elude detection during pre--marketing clinical trials. This study explores a novel approach that integrates an adverse event (AE) ontology…

Knowledge graph embedding (KGE), aiming to embed entities and relations into low-dimensional vectors, has attracted wide attention recently. However, the existing research is mainly based on the black-box neural models, which makes it…

计算与语言 · 计算机科学 2020-11-13 Xiaoyu Kou , Yankai Lin , Yuntao Li , Jiahao Xu , Peng Li , Jie Zhou , Yan Zhang

Adverse drug events (ADEs) are a major safety issue in clinical trials. Thus, predicting ADEs is key to developing safer medications and enhancing patient outcomes. To support this effort, we introduce CT-ADE, a dataset for multilabel ADE…

The development of deep neural networks has improved representation learning in various domains, including textual, graph structural, and relational triple representations. This development opened the door to new relation extraction beyond…

计算与语言 · 计算机科学 2022-12-22 Masaki Asada

Representation learning provides new and powerful graph analytical approaches and tools for the highly valued data science challenge of mining knowledge graphs. Since previous graph analytical methods have mostly focused on homogeneous…

To date, there are no effective treatments for most neurodegenerative diseases. Knowledge graphs can provide comprehensive and semantic representation for heterogeneous data, and have been successfully leveraged in many biomedical…

人工智能 · 计算机科学 2022-11-30 Yi Nian , Xinyue Hu , Rui Zhang , Jingna Feng , Jingcheng Du , Fang Li , Yong Chen , Cui Tao

Attention-Deficit/Hyperactivity Disorder (ADHD) is a challenging disorder to study due to its complex symptomatology and diverse contributing factors. To explore how we can gain deeper insights on this topic, we performed a network analysis…

社会与信息网络 · 计算机科学 2025-04-16 Hakan T. Otal , Stephen V. Faraone , M. Abdullah Canbaz

Aspect-based sentiment analysis (ABSA) is a fine-grained task of sentiment analysis. To better comprehend long complicated sentences and obtain accurate aspect-specific information, linguistic and commonsense knowledge are generally…

计算与语言 · 计算机科学 2023-03-15 Qihuang Zhong , Liang Ding , Juhua Liu , Bo Du , Hua Jin , Dacheng Tao

Increasing amounts of freely available data both in textual and relational form offers exploration of richer document representations, potentially improving the model performance and robustness. An emerging problem in the modern era is fake…

计算与语言 · 计算机科学 2022-02-16 Boshko Koloski , Timen Stepišnik-Perdih , Marko Robnik-Šikonja , Senja Pollak , Blaž Škrlj

Graph neural networks (GNNs) are powerful machine learning models designed to handle irregularly structured data. However, their generic design often proves inadequate for analyzing brain connectomes in Alzheimer's Disease (AD),…

机器学习 · 计算机科学 2024-12-10 Zhepeng Wang , Runxue Bao , Yawen Wu , Guodong Liu , Lei Yang , Liang Zhan , Feng Zheng , Weiwen Jiang , Yanfu Zhang

Adverse drug reactions (ADRs) are a major barrier to safe and effective pharmacotherapy and increasingly reflect higher order interactions between drugs, genetic background, and clinical phenotypes. Existing graph based approaches usually…

定量方法 · 定量生物学 2025-12-02 Ze Cai , Haotian Tang , Shuai Gao , Binbin Zhou , Junhan Zhao , Jun Wen

Biomedical Knowledge Graphs (BKGs) integrate diverse datasets to elucidate complex relationships within the biomedical field. Effective link prediction on these graphs can uncover valuable connections, such as potential novel drug-disease…

计算与语言 · 计算机科学 2025-07-01 Tien Dang , Viet Thanh Duy Nguyen , Minh Tuan Le , Truong-Son Hy

Adverse drug events (ADEs) are a serious health problem that can be life-threatening. While a lot of studies have been performed on detect correlation between a drug and an AE, limited studies have been conducted on personalized ADE risk…

机器学习 · 计算机科学 2021-04-20 Jinhe Shi , Xiangyu Gao , Chenyu Ha , Yage Wang , Guodong Gao , Yi Chen

Recent works show that the graph structure of sentences, generated from dependency parsers, has potential for improving event detection. However, they often only leverage the edges (dependencies) between words, and discard the dependency…

计算与语言 · 计算机科学 2021-05-06 Sanghamitra Dutta , Liang Ma , Tanay Kumar Saha , Di Lu , Joel Tetreault , Alejandro Jaimes

Natural language processing (NLP) is utilized in a wide range of fields, where words in text are typically transformed into feature vectors called embeddings. BioConceptVec is a specific example of embeddings tailored for biology, trained…

Scene text recognition has attracted particular research interest because it is a very challenging problem and has various applications. The most cutting-edge methods are attentional encoder-decoder frameworks that learn the alignment…

计算机视觉与模式识别 · 计算机科学 2019-08-27 Xiaoxue Chen , Tianwei Wang , Yuanzhi Zhu , Lianwen Jin , Canjie Luo

Graph Neural Networks (GNNs) have been widely studied for graph data representation and learning. However, existing GNNs generally conduct context-aware learning on node feature representation only which usually ignores the learning of edge…

机器学习 · 计算机科学 2019-10-07 Bo Jiang , Leiling Wang , Jin Tang , Bin Luo

Background. Previous state-of-the-art systems on Drug Name Recognition (DNR) and Clinical Concept Extraction (CCE) have focused on a combination of text "feature engineering" and conventional machine learning algorithms such as conditional…

计算与语言 · 计算机科学 2018-06-26 Inigo Jauregi Unanue , Ehsan Zare Borzeshi , Massimo Piccardi