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In this paper, we suggested eleven protein targets to be used as possible vaccines against Plasmodium falciparum causative agent of almost two to three million deaths per year. A comprehensive analysis of protein target have been selected…

基因组学 · 定量生物学 2010-09-30 Raul Isea

Malaria is mosquito-borne blood disease caused by parasites of the genus Plasmodium. Conventional diagnostic tool for malaria is the examination of stained blood cell of patient in microscope. The blood to be tested is placed in a slide and…

图像与视频处理 · 电气工程与系统科学 2018-03-30 Suman Kunwar

The organization and mining of malaria genomic and post-genomic data is highly motivated by the necessity to predict and characterize new biological targets and new drugs. Biological targets are sought in a biological space designed from…

To have the greatest impact, public health initiatives must be made using evidence-based decision-making. Machine learning Algorithms are created to gather, store, process, and analyse data to provide knowledge and guide decisions. A…

机器学习 · 计算机科学 2022-09-28 Imen Jdey , Ghazala Hcini , Hela Ltifi

Accurate detection of Plasmodium falciparum in Giemsa-stained blood smears is an essential component of reliable malaria diagnosis, especially in developing countries. Deep learning-based object detection methods have demonstrated strong…

计算机视觉与模式识别 · 计算机科学 2025-11-17 Frauke Wilm , Luis Carlos Rivera Monroy , Mathias Öttl , Lukas Mürdter , Leonid Mill , Andreas Maier

Malaria is a serious disease caused by the Plasmodium parasite that transmitted through the bite of a female Anopheles mosquito and invades human erythrocytes. Malaria must be recognized precisely in order to treat the patient in time and…

图像与视频处理 · 电气工程与系统科学 2019-10-01 Julisa Bana Abraham

Background: Phage therapy shows promise for treating antibiotic-resistant Klebsiella infections. Identifying phage depolymerases that target Klebsiella capsular polysaccharides is crucial, as these capsules contribute to biofilm formation…

基因组学 · 定量生物学 2025-01-29 George Wright , Slawomir Michniewski , Eleanor Jameson , Fayyaz ul Amir Afsar Minhas

Malaria microscopy, microscopic examination of stained blood slides to detect parasite Plasmodium, is considered to be a gold-standard for detecting life-threatening disease malaria. Detecting the plasmodium parasite requires a skilled…

图像与视频处理 · 电气工程与系统科学 2021-02-18 Qazi Ammar Arshad , Mohsen Ali , Saeed-ul Hassan , Chen Chen , Ayisha Imran , Ghulam Rasul , Waqas Sultani

Due to the rise in antimicrobial resistance, identifying novel compounds with antibiotic potential is crucial for combatting this global health issue. However, traditional drug development methods are costly and inefficient. Recognizing the…

生物大分子 · 定量生物学 2025-02-18 Gen Zhou , Sugitha Janarthanan , Yutong Lu , Pingzhao Hu

Improving the efficiency of malaria diagnosis is one of the main goals of current malaria research. We have recently developed a magneto-optical (MO) method which allows high-sensitivity detection of malaria pigment (hemozoin) crystals via…

Malaria remains a prevalent health concern in regions with tropical and subtropical climates. The cause of malaria is the Plasmodium parasite, which is transmitted through the bites of infected female Anopheles mosquitoes. Traditional…

计算机视觉与模式识别 · 计算机科学 2025-12-30 Md. Ismiel Hossen Abir , Awolad Hossain

Protein function prediction is a pivotal task in drug discovery, significantly impacting the development of effective and safe therapeutics. Traditional machine learning models often struggle with the complexity and variability inherent in…

机器学习 · 计算机科学 2024-09-24 Bohao Xu , Yingzhou Lu , Yoshitaka Inoue , Namkyeong Lee , Tianfan Fu , Jintai Chen

A wide range of methods currently exist for testing the presence of malaria, each with its own advantages and disadvantages. New technologies are urgently needed to develop more effective diagnosis tools to fight and eradicate malaria.…

医学物理 · 物理学 2025-08-26 A. S. Kiyumbi , M. S. Tame

Malaria remains a major health threat in low-resource regions and rapid diagnostic tests often lack the sensitivity required for early detection. To address this and help establish more sensitive testing devices, we develop a predictive…

光学 · 物理学 2026-01-15 A. S. Kiyumbi , M. S. Tame

Automated malaria diagnosis is a difficult but high-value target for machine learning (ML), and effective algorithms could save many thousands of children's lives. However, current ML efforts largely neglect crucial use case constraints and…

机器学习 · 计算机科学 2023-07-06 Charles B. Delahunt , Noni Gachuhi , Matthew P. Horning

The analysis and counting of blood cells in a microscope image can provide useful information concerning to the health of a person. In particular, morphological analysis of red blood cells deformations can effectively detect important…

计算机与社会 · 计算机科学 2013-12-05 Pramit Ghosh , Debotosh Bhattacharjee , Mita Nasipuri , Dipak Kumar Basu

Falciparum malaria is a major parasitic disease causing widespread morbidity and mortality globally. Artemisinin derivatives---the most effective and widely-used antimalarials that have helped reduce the burden of malaria by 60% in some…

In an era of escalating cyber threats, malware poses significant risks to individuals and organizations, potentially leading to data breaches, system failures, and substantial financial losses. This study addresses the urgent need for…

密码学与安全 · 计算机科学 2025-01-28 Marzieh Esnaashari , Nima Moradi

A timely immunization can be effective against certain diseases and can save thousands of lives. However, for some diseases it has been difficult, so far, to develop an efficient vaccine. Malaria, a tropical disease caused by a parasite of…

基因组学 · 定量生物学 2016-11-08 Raul Isea , Rafael Mayo-Garcia , Silvia Restrepo
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