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The evaluation of lymph node metastases plays a crucial role in achieving precise cancer staging, influencing subsequent decisions regarding treatment options. Lymph node detection poses challenges due to the presence of unclear boundaries…

计算机视觉与模式识别 · 计算机科学 2024-06-07 Sofija Engelson , Jan Ehrhardt , Timo Kepp , Joshua Niemeijer , Heinz Handels

Efficient and precise quantification of lymphocytes in histopathology slides is imperative for the characterization of the tumor microenvironment and immunotherapy response insights. We developed a data-centric optimization pipeline that…

图像与视频处理 · 电气工程与系统科学 2024-05-24 Amine Marzouki , Zhuxian Guo , Qinghe Zeng , Camille Kurtz , Nicolas Loménie

Pathological lymph node delineation is crucial in cancer diagnosis, progression assessment, and treatment planning. The MICCAI 2023 Lymph Node Quantification Challenge published the first public dataset for pathological lymph node…

计算机视觉与模式识别 · 计算机科学 2024-06-24 Stefan M. Fischer , Johannes Kiechle , Daniel M. Lang , Jan C. Peeken , Julia A. Schnabel

This study integrates PET metabolic information with CT anatomical structures to establish a 3D multimodal segmentation dataset for lymphoma based on whole-body FDG PET/CT examinations, which bridges the gap of the lack of standardised…

图像与视频处理 · 电气工程与系统科学 2025-12-08 Jiajun Ding , Beiyao Zhu , Xiaosheng Liu , Lishen Zhang , Zhao Liu

With the advent of novel cancer treatment options such as immunotherapy, studying the tumour immune micro-environment (TIME) is crucial to inform on prognosis and understand potential response to therapeutic agents. A key approach to…

In pathological research, education, and clinical practice, the decision-making process based on pathological images is critically important. This significance extends to digital pathology image analysis: its adequacy is demonstrated by the…

图像与视频处理 · 电气工程与系统科学 2024-08-19 Zhi-Bo Liu , Xiaobo Pang , Jizhao Wang , Shuai Liu , Chen Li

Timely and accurate lymphoma diagnosis is essential for guiding cancer treatment. Standard diagnostic practice combines hematoxylin and eosin (HE)-stained whole slide images with immunohistochemistry, flow cytometry, and molecular genetic…

Multiplex immunofluorescence and immunohistochemistry benefit patients by allowing cancer pathologists to identify several proteins expressed on the surface of cells, enabling cell classification, better understanding of the tumour…

计算机视觉与模式识别 · 计算机科学 2021-07-19 Jessica Cooper , In Hwa Um , Ognjen Arandjelović , David J Harrison

Automatic detection of lymphocyte in H&E images is a necessary first step in lots of tissue image analysis algorithms. An accurate and robust automated lymphocyte detection approach is of great importance in both computer science and…

计算机视觉与模式识别 · 计算机科学 2016-12-13 Jianxu Chen , Chukka Srinivas

Advances in optical microscopy scanning have significantly contributed to computational pathology (CPath) by converting traditional histopathological slides into whole slide images (WSIs). This development enables comprehensive digital…

图像与视频处理 · 电气工程与系统科学 2024-11-19 Xitong Ling , Yuanyuan Lei , Jiawen Li , Junru Cheng , Wenting Huang , Tian Guan , Jian Guan , Yonghong He

Metastatic presence in lymph nodes is one of the most important prognostic variables of breast cancer. The current diagnostic procedure for manually reviewing sentinel lymph nodes, however, is very time-consuming and subjective.…

计算机视觉与模式识别 · 计算机科学 2016-08-05 Richard Chen , Yating Jing , Hunter Jackson

Breast cancer is the most common invasive cancer in women, affecting more than 10% of women worldwide. Microscopic analysis of a biopsy remains one of the most important methods to diagnose the type of breast cancer. This requires…

The histological assessment of human tissue has emerged as the key challenge for detection and treatment of cancer. A plethora of different data sources ranging from tissue microarray data to gene expression, proteomics or metabolomics data…

计算机视觉与模式识别 · 计算机科学 2016-01-05 Thomas J. Fuchs , Joachim M. Buhmann

Recent studies have shown promising results in using Deep Learning to detect malignancy in whole slide imaging. However, they were limited to just predicting positive or negative finding for a specific neoplasm. We attempted to use Deep…

计算机视觉与模式识别 · 计算机科学 2018-11-08 Hanadi El Achi , Tatiana Belousova , Lei Chen , Amer Wahed , Iris Wang , Zhihong Hu , Zeyad Kanaan , Adan Rios , Andy N. D. Nguyen

Recent advancements in Digital Pathology (DP), particularly through artificial intelligence and Foundation Models, have underscored the importance of large-scale, diverse, and richly annotated datasets. Despite their critical role, publicly…

图像与视频处理 · 电气工程与系统科学 2025-05-20 Dmitry Nechaev , Alexey Pchelnikov , Ekaterina Ivanova

Histopathology whole slide images (WSIs) are being widely used to develop deep learning-based diagnostic solutions, especially for precision oncology. Most of these diagnostic softwares are vulnerable to biases and impurities in the…

图像与视频处理 · 电气工程与系统科学 2024-10-01 Abhijeet Patil , Harsh Diwakar , Jay Sawant , Nikhil Cherian Kurian , Subhash Yadav , Swapnil Rane , Tripti Bameta , Amit Sethi

Deep learning has recently gained popularity in digital pathology due to its high prediction quality. However, the medical domain requires explanation and insight for a better understanding beyond standard quantitative performance…

Background: Recruitment for cohorts involving complex liver diseases, such as hepatocellular carcinoma and liver cirrhosis, often requires interpreting semantically complex criteria. Traditional manual screening methods are time-consuming…

人工智能 · 计算机科学 2025-02-27 Xiongbin Gui , Hanlin Lv , Xiao Wang , Longting Lv , Yi Xiao , Lei Wang

Histopathology refers to the examination by a pathologist of biopsy samples. Histopathology images are captured by a microscope to locate, examine, and classify many diseases, such as different cancer types. They provide a detailed view of…

图像与视频处理 · 电气工程与系统科学 2020-11-12 Naira Elazab , Hassan Soliman , Shaker El-Sappagh , S. M. Riazul Islam , Mohammed Elmogy
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