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While Multiple Instance Learning (MIL) has shown promising results in digital Pathology Whole Slide Image (WSI) classification, such a paradigm still faces performance and generalization problems due to challenges in high computational…

计算机视觉与模式识别 · 计算机科学 2023-03-16 Honglin Li , Chenglu Zhu , Yunlong Zhang , Yuxuan Sun , Zhongyi Shui , Wenwei Kuang , Sunyi Zheng , Lin Yang

Accurate segmentation of polyps and skin lesions is essential for diagnosing colorectal and skin cancers. While various segmentation methods for polyps and skin lesions using fully supervised deep learning techniques have been developed,…

计算机视觉与模式识别 · 计算机科学 2025-04-03 Encheng Su , Hu Cao , Alois Knoll

Digital histopathology whole slide images (WSIs) provide gigapixel-scale high-resolution images that are highly useful for disease diagnosis. However, digital histopathology image analysis faces significant challenges due to the limited…

计算机视觉与模式识别 · 计算机科学 2026-02-13 Bodong Zhang , Xiwen Li , Hamid Manoochehri , Xiaoya Tang , Deepika Sirohi , Beatrice S. Knudsen , Tolga Tasdizen

Lifelong learning for whole slide images (WSIs) poses the challenge of training a unified model to perform multiple WSI-related tasks, such as cancer subtyping and tumor classification, in a distributed, continual fashion. This is a…

计算机视觉与模式识别 · 计算机科学 2025-04-23 Doanh C. Bui , Hoai Luan Pham , Vu Trung Duong Le , Tuan Hai Vu , Van Duy Tran , Yasuhiko Nakashima

Image-level weakly-supervised semantic segmentation (WSSS) reduces the usually vast data annotation cost by surrogate segmentation masks during training. The typical approach involves training an image classification network using global…

计算机视觉与模式识别 · 计算机科学 2024-06-10 Arvi Jonnarth , Yushan Zhang , Michael Felsberg

Tissue-level semantic segmentation is a vital step in computational pathology. Fully-supervised models have already achieved outstanding performance with dense pixel-level annotations. However, drawing such labels on the giga-pixel whole…

Most weakly supervised semantic segmentation (WSSS) methods follow the pipeline that generates pseudo-masks initially and trains the segmentation model with the pseudo-masks in fully supervised manner after. However, we find some matters…

计算机视觉与模式识别 · 计算机科学 2021-09-08 Yi Li , Zhanghui Kuang , Liyang Liu , Yimin Chen , Wayne Zhang

Supervised deep learning methods have achieved considerable success in medical image analysis, owing to the availability of large-scale and well-annotated datasets. However, creating such datasets for whole slide images (WSIs) in…

计算机视觉与模式识别 · 计算机科学 2024-06-10 Hao Wang , Euijoon Ahn , Jinman Kim

Weakly-supervised learning (WSL) has recently triggered substantial interest as it mitigates the lack of pixel-wise annotations. Given global image labels, WSL methods yield pixel-level predictions (segmentations), which enable to interpret…

计算机视觉与模式识别 · 计算机科学 2021-10-12 Soufiane Belharbi , Jérôme Rony , Jose Dolz , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

Whole-slide image (WSI) classification in computational pathology is commonly formulated as slide-level Multiple Instance Learning (MIL) with a single global bag representation. However, slide-level MIL is fundamentally underconstrained:…

The advancement of digital pathology, particularly through computational analysis of whole slide images (WSI), is poised to significantly enhance diagnostic precision and efficiency. However, the large size and complexity of WSIs make it…

计算机视觉与模式识别 · 计算机科学 2024-11-14 Ravi Kant Gupta , Dadi Dharani , Shambhavi Shanker , Amit Sethi

High-resolution hyperspectral images (HSIs) contain the response of each pixel in different spectral bands, which can be used to effectively distinguish various objects in complex scenes. While HSI cameras have become low cost, algorithms…

计算机视觉与模式识别 · 计算机科学 2021-07-21 Yuxing Huang , Shaodi You , Ying Fu , Qiu Shen

The application of deep learning to medical image segmentation has been hampered due to the lack of abundant pixel-level annotated data. Few-shot Semantic Segmentation (FSS) is a promising strategy for breaking the deadlock. However, a…

计算机视觉与模式识别 · 计算机科学 2021-10-26 Xiaoang Shen , Guokai Zhang , Huilin Lai , Jihao Luo , Jianwei Lu , Ye Luo

Deep neural networks usually require accurate and a large number of annotations to achieve outstanding performance in medical image segmentation. One-shot segmentation and weakly-supervised learning are promising research directions that…

图像与视频处理 · 电气工程与系统科学 2021-11-23 Wenhui Lei , Qi Su , Ran Gu , Na Wang , Xinglong Liu , Guotai Wang , Xiaofan Zhang , Shaoting Zhang

Deep learning methods such as convolutional neural networks (CNNs) are difficult to directly utilize to analyze whole slide images (WSIs) due to the large image dimensions. We overcome this limitation by proposing a novel two-stage…

图像与视频处理 · 电气工程与系统科学 2021-06-15 Shivam Kalra , Mohammed Adnan , Sobhan Hemati , Taher Dehkharghanian , Shahryar Rahnamayan , Hamid Tizhoosh

Breast cancer is the most prevalent cancer in women worldwide. Histopathology image analysis serves as the gold standard for cancer diagnosis. In this regard, whole-slide imaging (WSI), a revolutionary technology in digital pathology,…

统计方法学 · 统计学 2026-04-21 Baichen Yu , Xuetong Li , Jing Zhou , Hansheng Wang

We propose a Deep learning-based weak label learning method for analyzing whole slide images (WSIs) of Hematoxylin and Eosin (H&E) stained tumor tissue not requiring pixel-level or tile-level annotations using Self-supervised pre-training…

图像与视频处理 · 电气工程与系统科学 2023-06-29 Yoni Schirris , Efstratios Gavves , Iris Nederlof , Hugo Mark Horlings , Jonas Teuwen

We present a novel approach to train pixel resolution segmentation models on whole slide images in a weakly supervised setup. The model is trained to classify patches extracted from slides. This leads the training to be made under noisy…

图像与视频处理 · 电气工程与系统科学 2019-07-19 Nicolas Pinchaud

Weakly-supervised instance segmentation (WSIS) has been considered as a more challenging task than weakly-supervised semantic segmentation (WSSS). Compared to WSSS, WSIS requires instance-wise localization, which is difficult to extract…

计算机视觉与模式识别 · 计算机科学 2022-03-30 Beomyoung Kim , Youngjoon Yoo , Chaeeun Rhee , Junmo Kim

Various multi-instance learning (MIL) based approaches have been developed and successfully applied to whole-slide pathological images (WSI). Existing MIL methods emphasize the importance of feature aggregators, but largely neglect the…

计算机视觉与模式识别 · 计算机科学 2025-05-13 Yicheng Song , Tiancheng Lin , Die Peng , Su Yang , Yi Xu