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Although atrial fibrillation (AF), a common arrhythmia, frequently presents in patients with underlying valvular disease, its hemodynamic contributions are not fully understood. The present work aimed to computationally study how physical…

流体动力学 · 物理学 2016-07-27 Stefania Scarsoglio , Andrea Saglietto , Fiorenzo Gaita , Luca Ridolfi , Matteo Anselmino

Battery models generally fall into two categories: physics-based models and ECM models. Physics-based Doyle-Fuller-Newman (DFN) models can accurately simulate the battery internal electrochemical processes, but to properly account for…

应用物理 · 物理学 2026-05-20 Han Yuan , Shen Li , Tao Zhu , Simon O'Kane , Carlos Garcia , Gregory Offer , Monica Marinescu

An electrocardiogram (EKG) is a common, non-invasive test that measures the electrical activity of a patient's heart. EKGs contain useful diagnostic information about patient health that may be absent from other electronic health record…

This paper presents a comprehensive mathematical model of a servopneumatic system, aimed at its consolidation in literature. The work exploits system's friction forces, temperature and pressure evolution, heat transfer, leakage between…

系统与控制 · 电气工程与系统科学 2020-11-16 Rodrigo Trentini , Daniel Rafael dos Santos , Yuri Roberto Ferreira

Computer simulation is an important tool for scientific progress, especially when lab experiments are either extremely costly and difficult or lack the required resolution. However, all of the simulation methods come with limitations. In…

流体动力学 · 物理学 2023-08-04 Edward R. Smith , Panagiotis E. Theodorakis

We present the implementation and application of a multiphysics simulation technique to carrier dynamics under electromagnetic excitation in supported two-dimensional electronic systems. The technique combines ensemble Monte Carlo (EMC) for…

介观与纳米尺度物理 · 物理学 2014-05-21 N. Sule , K. J. Willis , S. C. Hagness , I. Knezevic

Leveraging big data for patient care is promising in many medical fields such as cardiovascular health. For example, hemodynamic biomarkers like wall shear stress could be assessed from patient-specific medical images via machine learning…

计算机视觉与模式识别 · 计算机科学 2025-08-27 Julian Suk , Jolanda J. Wentzel , Patryk Rygiel , Joost Daemen , Daniel Rueckert , Jelmer M. Wolterink

Precision psychiatry aspires to elucidate brain-based biomarkers of psychopathology to bolster disease risk assessment and treatment development. To this end, functional magnetic resonance imaging (fMRI) has helped triangulate brain…

神经元与认知 · 定量生物学 2026-01-23 Cole Korponay

This paper worked towards modeling blood platelets. Blood platelets, also known as thrombocytes, play a key role in blood clotting which is a vital human function. Furthermore, the role of these entities in strokes, myocardial infarctions,…

细胞行为 · 定量生物学 2012-06-05 Vijay Viswanathan , Seetha Pothapragada

Background and Objective: This proof of concept study investigates mathematical modelling of blood flow and oxygen transport in cerebral microcirculation, focusing on understanding hemodynamic responses. By coupling oxygen transport models…

数值分析 · 数学 2024-11-19 Maryam Samavaki , Santtu Söderholm , Arash Zarrin Nia , Sampsa Pursiainen

In fractured natural formations, the equations governing fluid flow and geomechanics are strongly coupled. Hydrodynamical properties depend on the mechanical configuration, and they are therefore difficult to accurately resolve using…

数值分析 · 数学 2021-04-07 Matteo Cusini , Joshua A. White , Nicola Castelletto , Randolph R. Settgast

Modeling of fluid flows requires corresponding adequate and effective approaches that would account for multiscale nature of the considered physics. Despite the tremendous growth of computational power in the past decades, modeling of fluid…

流体动力学 · 物理学 2025-06-24 Arsen S. Iskhakov , Nam T. Dinh

Developing new methods for predicting electromagnetic instabilities in cardiac activity is of primary importance. However, we still need a comprehensive view of the heart's magnetic activity at the tissue scale. To fill this gap, we present…

In the emerging field of 3D bioprinting, cell damage due to large deformations is considered a main cause for cell death and loss of functionality inside the printed construct. Those deformations, in turn, strongly depend on the…

When they are damaged or injured, soft biological tissues are able to self-repair and heal. Mechanics is critical during the healing process, as the damaged extracellular matrix (ECM) tends to be replaced with a new undamaged ECM supporting…

计算工程、金融与科学 · 计算机科学 2021-12-08 Di Zuo , Yiqian He , Stéphane Avril , Haitian Yang , Klaus Hackl

In CFD simulations of two-phase flows, accurate drag force modeling is essential for predicting particle dynamics. However, a generally valid formulation is lacking, as all available drag force correlations have been established for…

流体动力学 · 物理学 2023-02-08 Gizem Ozler , Mustafa Demircioglu , Holger Grosshans

The development and progression of abdominal aortic aneurysms (AAA) are related to complex flow patterns and wall-shear-driven mechanobiological stimuli, yet the quantitative relationship between aneurysmal geometry and hemodynamics remains…

This paper presents the principal challenges and opportunities associated with computational biomechanics research. The underlying cognitive control involved in the process of human motion is inherently complex, dynamic, multidimensional,…

The design of microfluidic devices is a cumbersome and tedious process that can be significantly improved by simulation. Methods based on Computational Fluid Dynamics (CFD) are considered state-of-the-art, but require extensive compute time…

计算工程、金融与科学 · 计算机科学 2024-01-17 Michel Takken , Robert Wille

Three-dimensional cardiovascular fluid dynamics simulations typically require computation of several cardiac cycles before they reach a periodic solution, rendering them computationally expensive. Furthermore, there is currently no…

计算工程、金融与科学 · 计算机科学 2021-06-28 Martin R. Pfaller , Jonathan Pham , Nathan M. Wilson , David W. Parker , Alison L. Marsden
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