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In practice, many medical datasets have an underlying taxonomy defined over the disease label space. However, existing classification algorithms for medical diagnoses often assume semantically independent labels. In this study, we aim to…

计算机视觉与模式识别 · 计算机科学 2022-09-14 Zhen Yu , Toan Nguyen , Yaniv Gal , Lie Ju , Shekhar S. Chandra , Lei Zhang , Paul Bonnington , Victoria Mar , Zhiyong Wang , Zongyuan Ge

Leukemia, the cancer of blood cells, originates in the blood-forming cells of the bone marrow. In Chronic Myeloid Leukemia (CML) conditions, the cells partially become mature that look like normal white blood cells but do not resist…

基因组学 · 定量生物学 2023-02-09 Madiha Hameed , Muhammad Bilal , Tuba Majid , Abdul Majid , Asifullah Khan

We propose a cell segmentation method for analyzing images of densely clustered cells. The method combines the strengths of marker-controlled watershed transformation and a convolutional neural network (CNN). We demonstrate the method…

图像与视频处理 · 电气工程与系统科学 2020-04-06 Filip Lux , Petr Matula

Despite fluorescent cell-labelling being widely employed in biomedical studies, some of its drawbacks are inevitable, with unsuitable fluorescent probes or probes inducing a functional change being the main limitations. Consequently, the…

Multiplex Imaging (MI) enables the simultaneous visualization of multiple biological markers in separate imaging channels at subcellular resolution, providing valuable insights into cell-type heterogeneity and spatial organization. However,…

图像与视频处理 · 电气工程与系统科学 2024-11-07 Simon Gutwein , Daria Lazic , Thomas Walter , Sabine Taschner-Mandl , Roxane Licandro

Cellular Electron Cryo-Tomography (CECT) is a powerful imaging technique for the 3D visualization of cellular structure and organization at submolecular resolution. It enables analyzing the native structures of macromolecular complexes and…

定量方法 · 定量生物学 2018-05-16 Chang Liu , Xiangrui Zeng , Ruogu Lin , Xiaodan Liang , Zachary Freyberg , Eric Xing , Min Xu

Blood vessels (BVs) play a critical role in the Tumor Micro-Environment (TME), potentially influencing cancer progression and treatment response. However, manually quantifying BVs in Hematoxylin and Eosin (H&E) stained images is challenging…

图像与视频处理 · 电气工程与系统科学 2025-01-27 Jiaqi Lv , Stefan S Antonowicz , Shan E Ahmed Raza

The application of machine learning techniques to the medical domain is especially challenging due to the required level of precision and the incurrence of huge risks of minute errors. Employing these techniques to a more complex subdomain…

计算机视觉与模式识别 · 计算机科学 2021-10-19 Ekta Gavas , Kaustubh Olpadkar

Molecular and genomic properties are critical in selecting cancer treatments to target individual tumors, particularly for immunotherapy. However, the methods to assess such properties are expensive, time-consuming, and often not routinely…

图像与视频处理 · 电气工程与系统科学 2022-11-29 Heather D. Couture

Modeling the 3D structures of cells and tissues is crucial in biology. Sequential cross-sectional images from electron microscopy provide high-resolution intracellular structure information. The segmentation of complex cell structures…

定量方法 · 定量生物学 2025-02-14 Jin Kousaka , Atsuko H. Iwane , Yuichi Togashi

Modeling of the red blood cell (RBC) shape is an integral part of the experimental and computer simulation investigations of light scattering by these cells for fundamental studies as well as diagnostic applications in techniques like…

生物物理 · 物理学 2024-06-18 Gaurav D. Bhabhor , Chetna Patel , Nishant Chhillar , Arun Anand , Kirit N. Lad

It is generally believed that the human visual system is biased towards the recognition of shapes rather than textures. This assumption has led to a growing body of work aiming to align deep models' decision-making processes with the…

计算机视觉与模式识别 · 计算机科学 2022-06-15 Adriano Lucieri , Fabian Schmeisser , Christoph Peter Balada , Shoaib Ahmed Siddiqui , Andreas Dengel , Sheraz Ahmed

This paper presents a deep learning framework for image classification aimed at increasing predictive performance for Cytotoxic Edema (CE) diagnosis in infants and children. The proposed framework includes two 3D network architectures…

The structure of grey matter has long been a key focus in neuroscience, as cell morphology varies by type and can be affected by neurological conditions. Understanding these variations is essential for studying brain function and disease.…

生物物理 · 物理学 2025-08-27 Charlie Aird-Rossiter , Hui Zhang , Daniel C. Alexander , Derek K. Jones , Marco Palombo

Accurate segmentation of gastrointestinal (GI) organs in magnetic resonance enterography (MRE) is critical for diagnosing inflammatory bowel disease (IBD). However, anatomical variability, class imbalance, and low tissue contrast hinder…

图像与视频处理 · 电气工程与系统科学 2026-04-21 Ashiqur Rahman , Md. Abu Sayed , Md Sharjis Ibne Wadud , Md. Abu Asad Al-Hafiz , Adam Mushtak , Muhammad E. H. Chowdhury

Important information that relates to a specific topic in a document is often organized in tabular format to assist readers with information retrieval and comparison, which may be difficult to provide in natural language. However, tabular…

计算机视觉与模式识别 · 计算机科学 2020-03-05 Xu Zhong , Elaheh ShafieiBavani , Antonio Jimeno Yepes

Human immune system contains white blood cells (WBC) that are good indicator of many diseases like bacterial infections, AIDS, cancer, spleen, etc. White blood cells have been sub classified into four types: monocytes, lymphocytes,…

图像与视频处理 · 电气工程与系统科学 2024-10-15 Rabia Asghar , Arslan Shaukat , Usman Akram , Rimsha Tariq

In hematology, computational models offer significant potential to improve diagnostic accuracy, streamline workflows, and reduce the tedious work of analyzing single cells in peripheral blood or bone marrow smears. However, clinical…

计算机视觉与模式识别 · 计算机科学 2024-04-09 Valentin Koch , Sophia J. Wagner , Salome Kazeminia , Ece Sancar , Matthias Hehr , Julia Schnabel , Tingying Peng , Carsten Marr

In biomedical imaging, deep learning-based methods are state-of-the-art for every modality (virtual slides, MRI, etc.) In histopathology, these methods can be used to detect certain biomarkers or classify lesions. However, such techniques…

Accurate and robust medical image classification is paramount for early disease diagnosis and treatment planning. However, challenges such as limited annotated data, high intra-class variability, and subtle inter-class differences often…

图像与视频处理 · 电气工程与系统科学 2026-05-22 Joao Florindo , Viviane Moura