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We consider error-correcting coding for deoxyribonucleic acid (DNA)-based storage using nanopore sequencing. We model the DNA storage channel as a sampling noise channel where the input data is chunked into $M$ short DNA strands, which are…

In this paper, we study achievable rates of concatenated coding schemes over a deoxyribonucleic acid (DNA) storage channel. Our channel model incorporates the main features of DNA-based data storage. First, information is stored on many,…

信息论 · 计算机科学 2020-05-04 Andreas Lenz , Lorenz Welter , Sven Puchinger

We study the amount of reliable information that can be stored in a DNA-based storage system with noisy sequencing, where each codeword is composed of short DNA molecules. We analyze a concatenated coding scheme, where the outer code is…

信息论 · 计算机科学 2026-05-19 Ran Tamir , Nir Weinberger , Albert Guillén i Fàbregas

The DNA storage channel is considered, in which a codeword is comprised of $M$ unordered DNA molecules. At reading time, $N$ molecules are sampled with replacement, and then each molecule is sequenced. A coded-index concatenated-coding…

信息论 · 计算机科学 2022-05-23 Nir Weinberger

In this paper, we consider the outer channel for DNA-based data storage. When transmitting over the outer channel, each DNA string is treated as a unit/symbol that would be either correctly received, or erased, or corrupted by uniformly…

信息论 · 计算机科学 2025-09-23 Xuan He , Yi Ding , Kui Cai , Guanghui Song , Bin Dai , Xiaohu Tang

Noisy shuffling channels capture the main characteristics of DNA storage systems where distinct segments of data are received out of order, after being corrupted by substitution errors. For realistic schemes with short-length segments,…

信息论 · 计算机科学 2024-10-07 Javad Haghighat , Tolga M. Duman

Decoding sequences that stem from multiple transmissions of a codeword over an insertion, deletion, and substitution channel is a critical component of efficient deoxyribonucleic acid (DNA) data storage systems. In this paper, we consider a…

Decoding sequences that stem from multiple transmissions of a codeword over an insertion, deletion, and substitution channel is a critical component of efficient deoxyribonucleic acid (DNA) data storage systems. In this paper, we consider a…

DNA data storage offers a high-density, long-term alternative to traditional storage systems, addressing the exponential growth of digital data. Composite DNA extends this paradigm by leveraging mixtures of nucleotides to increase storage…

信息论 · 计算机科学 2026-02-13 Busra Tegin , Tolga M Duman

Synchronization errors, such as insertions and deletions, present a fundamental challenge in DNA-based data storage systems, arising from both synthesis and sequencing noise. These channels are often modeled as…

信息论 · 计算机科学 2025-06-23 Ziv Aharoni , Henry D. Pfister

The errors occurring in DNA-based storage are correlated in nature, which is a direct consequence of the synthesis and sequencing processes. In this paper, we consider the memory-$k$ nanopore channel model recently introduced by Hamoum et…

信息论 · 计算机科学 2023-03-27 Issam Maarouf , Eirik Rosnes , Alexandre Graell i Amat

DNA, with remarkable properties of high density, durability, and replicability, is one of the most appealing storage media. Emerging DNA storage technologies use composite DNA letters, where information is represented by probability…

信息论 · 计算机科学 2025-03-26 Wenkai Zhang , Zhiying Wang

Due to the redundant nature of DNA synthesis and sequencing technologies, a basic model for a DNA storage system is a multi-draw "shuffling-sampling" channel. In this model, a random number of noisy copies of each sequence is observed at…

信息论 · 计算机科学 2021-12-06 Kel Levick , Reinhard Heckel , Ilan Shomorony

DNA-based data storage has been attracting significant attention due to its extremely high data storage density, low power consumption, and long duration compared to conventional data storage media. Despite the recent advancements in DNA…

信息论 · 计算机科学 2024-11-12 Yi Ding , Xuan He , Tuan Thanh Nguyen , Wentu Song , Zohar Yakhini , Eitan Yaakobi , Linqiang Pan , Xiaohu Tang , Kui Cai

Data storage in DNA is developing as a possible solution for archival digital data. Recently, to further increase the potential capacity of DNA-based data storage systems, the combinatorial composite DNA synthesis method was suggested. This…

信息论 · 计算机科学 2024-05-28 Omer Sabary , Inbal Preuss , Ryan Gabrys , Zohar Yakhini , Leon Anavy , Eitan Yaakobi

This work presents a theoretical analysis of the probability of successfully retrieving data encoded with MDS codes (e.g., Reed-Solomon codes) in DNA storage systems. We study this probability under independent and identically distributed…

信息论 · 计算机科学 2026-05-08 Serge Kas Hanna

We propose a novel coding scheme for DNA-based storage systems, called the shift-interleave (SI) coding, designed to correct insertion, deletion, and substitution (IDS) errors, as well as sequence losses. The SI coding scheme employs…

信息论 · 计算机科学 2024-01-29 Ryo Shibata , Haruhiko Kaneko

We propose a new coding scheme, called the delayed coding (DC) scheme, for channels with insertion, deletion, and substitution (IDS) errors. The proposed scheme employs delayed encoding and non-iterative detection and decoding strategies to…

信息论 · 计算机科学 2022-05-25 Ryo Shibata , Hiroyuki Yashima

In this paper, we propose a novel iterative encoding algorithm for DNA storage to satisfy both the GC balance and run-length constraints using a greedy algorithm. DNA strands with run-length more than three and the GC balance ratio far from…

信息论 · 计算机科学 2023-01-04 Seong-Joon Park , Yongwoo Lee , Jong-Seon No

A new family of codes, called clustering-correcting codes, is presented in this paper. This family of codes is motivated by the special structure of data that is stored in DNA-based storage systems. The data stored in these systems has the…

信息论 · 计算机科学 2019-03-12 Tal Shinkar , Eitan Yaakobi , Andreas Lenz , Antonia Wachter-Zeh
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