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Proteinoids are solidified gels made from poly(amino acids) based polymers that exhibit oscillatory electrical activity. It has been proposed that proteinoids are capable of performing analog computing as their electrical activity can be…

Proteinoids -- thermal proteins -- are produced by heating amino acids to their melting point and initiation of polymerisation to produce polymeric chains. Proteinoids swell in aqueous solution into hollow microspheres. The proteinoid…

新兴技术 · 计算机科学 2021-06-03 Andrew Adamatzky

Proteinoids are thermal proteins which form microspheres in water in presence of salt. Ensembles of proteinoid microspheres exhibit passive non-linear electrical properties and active neuron-like spiking of electrical potential. We propose…

新兴技术 · 计算机科学 2023-06-27 Panagiotis Mougkogiannis , Andrew Adamatzky

Proteins are polymers of amino acids. These macromolecules are synthesized by intracellular machines called ribosomes. Although the experimental investigation of protein synthesis has been a traditional area of research in molecular cell…

生物物理 · 物理学 2009-11-13 Aakash Basu , Debashish Chowdhury

Proteins are fundamental biological entities that play a key role in life activities. The amino acid sequences of proteins can be folded into stable 3D structures in the real physicochemical world, forming a special kind of…

机器学习 · 计算机科学 2023-01-04 Lirong Wu , Yufei Huang , Haitao Lin , Stan Z. Li

Proteins are macromolecules that mediate a significant fraction of the cellular processes that underlie life. An important task in bioengineering is designing proteins with specific 3D structures and chemical properties which enable…

定量方法 · 定量生物学 2022-05-31 Namrata Anand , Tudor Achim

Protein structure prediction is a challenging and unsolved problem in computer science. Proteins are the sequence of amino acids connected together by single peptide bond. The combinations of the twenty primary amino acids are the…

计算工程、金融与科学 · 计算机科学 2015-10-12 Mahmood A. Rashid , Firas Khatib , Abdul Sattar

Proteinoids, or thermal proteins, are inorganic entities formed by heating amino acids to their melting point and commencing polymerisation to form polymeric chains. Typically, their diameters range from 10 to 100 micron. Some amino acids…

新兴技术 · 计算机科学 2023-02-13 Panagiotis Mougkogiannis , Neil Phillips , Andrew Adamatzky

Proteins perform critical processes in all living systems: converting solar energy into chemical energy, replicating DNA, as the basis of highly performant materials, sensing and much more. While an incredible range of functionality has…

生物大分子 · 定量生物学 2021-09-29 Leonardo V. Castorina , Rokas Petrenas , Kartic Subr , Christopher W. Wood

Proteinoids, also known as thermal proteins, possess a fascinating ability to generate microspheres that exhibit electrical spikes resembling the action potentials of neurons. These spiking microspheres, referred to as protoneurons, hold…

新兴技术 · 计算机科学 2023-06-13 Panagiotis Mougkogiannis , Andrew Adamatzky

Just as physicists strive to develop a TOE (theory of everything), which explains and unifies the physical laws of the universe, the life-scientist wishes to uncover the TOE as it relates to cellular systems. This can only be achieved with…

Proteins, by virtue of their central role in most biological processes, represent one of the key subjects of the study of molecular evolution. Inherent to the indispensability of proteins for living cells is the fact that a given protein…

生物大分子 · 定量生物学 2007-05-23 Eric J. Deeds , Eugene I. Shakhnovich

Proteins are the fundamental macromolecules that play diverse and crucial roles in all living matter and have tremendous implications in healthcare, manufacturing, and biotechnology. Their functions are largely determined by the sequences…

生物大分子 · 定量生物学 2024-09-17 Boqiao Lai

Proteins are complex biomolecules that play a central role in various biological processes, making them critical targets for breakthroughs in molecular biology, medical research, and drug discovery. Deciphering their intricate, hierarchical…

机器学习 · 计算机科学 2025-05-09 Viet Thanh Duy Nguyen , Truong-Son Hy

Crystallography may be the gold standard of protein structure determination, but obtaining the necessary high-quality crystals is also in some ways akin to prospecting for the precious metal. The tools and models developed in soft matter…

软凝聚态物质 · 物理学 2016-02-10 Diana Fusco , Patrick Charbonneau

Two-dimensional electrophoresis of proteins has preceded, and accompanied, the birth of proteomics. Although it is no longer the only experimental scheme used in modern proteomics, it still has distinct features and advantages. The purpose…

基因组学 · 定量生物学 2011-09-15 Thierry Rabilloud , Cécile Lelong

While many good textbooks are available on Protein Structure, Molecular Simulations, Thermodynamics and Bioinformatics methods in general, there is no good introductory level book for the field of Structural Bioinformatics. This book aims…

Understanding protein solubility is essential for their functional applications. Computational methods for predicting protein solubility are crucial for reducing experimental costs and enhancing the efficiency and success rates of protein…

定量方法 · 定量生物学 2024-07-01 Yang Tan , Jia Zheng , Liang Hong , Bingxin Zhou

Background:Typically, proteins perform key biological functions by interacting with each other. As a consequence, predicting which protein pairs interact is a fundamental problem. Experimental methods are slow, expensive, and may be error…

生物大分子 · 定量生物学 2022-02-08 Leonardo Martini , Adriano Fazzone , Luca Becchetti

Colloids play an important role in fundamental science as well as in nature and technology. They have had a strong impact on the fundamental understanding of statistical physics. For example, colloids have helped to obtain a better…

软凝聚态物质 · 物理学 2025-02-27 Debasish Saha , Sonja Tarama , Hartmut Löwen , Stefan U. Egelhaaf
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