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While randomized controlled trials (RCTs) are the gold standard for estimating treatment effects in medical research, there is increasing use of and interest in using real-world data for drug development. One such use case is the…

统计方法学 · 统计学 2021-10-11 Devin Incerti , Michael T Bretscher , Ray Lin , Chris Harbron

This work presents a comparative study of existing and new techniques to detect knee injuries by leveraging Stanford's MRNet Dataset. All approaches are based on deep learning and we explore the comparative performances of transfer learning…

图像与视频处理 · 电气工程与系统科学 2020-10-06 David Azcona , Kevin McGuinness , Alan F. Smeaton

Epidemics and pandemics have ravaged human life since time. To combat these, novel ideas have always been created and deployed by humanity, with varying degrees of success. At this very moment, the COVID-19 pandemic is the singular global…

The worldwide impact of the recent COVID-19 pandemic has been substantial, necessitating the development of accurate forecasting models to predict the spread and course of a pandemic. Previous methods for outbreak forecasting have faced…

机器学习 · 计算机科学 2024-08-28 Ashutosh Anshul , Jhalak Gupta , Mohammad Zia Ur Rehman , Nagendra Kumar

There is increasing interest in combining information from experimental studies, including randomized and single-group trials, with information from external experimental or observational data sources. Such efforts are usually motivated by…

统计方法学 · 统计学 2026-04-23 Lawson Ung , Guanbo Wang , Sebastien Haneuse , Miguel A. Hernán , Issa J. Dahabreh

The COVID-19 crisis has shown that we can only prevent the risk of mass contagion through timely, large-scale, coordinated, and decisive actions. However, frequently the models used by experts [from whom decision-makers get their main…

应用统计 · 统计学 2021-03-08 Mauricio Herrera

The global spread of COVID-19 had severe consequences for public health and the world economy. The quick onset of the pandemic highlighted the potential benefits of cheap and deployable pre-screening methods to monitor the prevalence of the…

声音 · 计算机科学 2023-09-12 Andrej Jovanović , Mario Mihaly , Lennon Donaldson

The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has posed significant health challenges worldwide. While respiratory symptoms have been the primary focus, emerging evidence has highlighted the impact of COVID-19 on…

机器学习 · 计算机科学 2023-10-03 Maitham G. Yousif , Fadhil G. Al-Amran , Salman Rawaf , Mohammad Abdulla Grmt

A critical step in the fight against COVID-19, which continues to have a catastrophic impact on peoples lives, is the effective screening of patients presented in the clinics with severe COVID-19 symptoms. Chest radiography is one of the…

图像与视频处理 · 电气工程与系统科学 2022-08-09 Tomasz Szczepański , Arkadiusz Sitek , Tomasz Trzciński , Szymon Płotka

Purpose: Accurate segmentation of lung and infection in COVID-19 CT scans plays an important role in the quantitative management of patients. Most of the existing studies are based on large and private annotated datasets that are…

图像与视频处理 · 电气工程与系统科学 2021-06-09 Jun Ma , Yixin Wang , Xingle An , Cheng Ge , Ziqi Yu , Jianan Chen , Qiongjie Zhu , Guoqiang Dong , Jian He , Zhiqiang He , Yuntao Zhu , Ziwei Nie , Xiaoping Yang

Background: Acute kidney injury (AKI) is a clinical syndrome affecting almost one fifth of hospitalized patients, as well as more than half of the patients who are admitted to the intensive care unit (ICU). Stratifying AKI patients into…

COVID-19 is extremely contagious and its rapid growth has drawn attention towards its early diagnosis. Early diagnosis of COVID-19 enables healthcare professionals and government authorities to break the chain of transition and flatten the…

图像与视频处理 · 电气工程与系统科学 2024-11-19 Sumera Rounaq , Shahid Munir Shah , Mahmoud Aljawarneh

The COVID-19 pandemic represents the most significant public health disaster since the 1918 influenza pandemic. During pandemics such as COVID-19, timely and reliable spatio-temporal forecasting of epidemic dynamics is crucial. Deep…

机器学习 · 计算机科学 2020-11-25 Lijing Wang , Aniruddha Adiga , Srinivasan Venkatramanan , Jiangzhuo Chen , Bryan Lewis , Madhav Marathe

The COVID-19 pandemic continues to have a devastating effect on the health and well-being of the global population. Apart from the global health crises, the pandemic has also caused significant economic and financial difficulties and…

图像与视频处理 · 电气工程与系统科学 2023-02-08 Ashkan Ebadi , Pengcheng Xi , Alexander MacLean , Stéphane Tremblay , Sonny Kohli , Alexander Wong

COVID-19 clinical presentation and prognosis are highly variable, ranging from asymptomatic and paucisymptomatic cases to acute respiratory distress syndrome and multi-organ involvement. We developed a hybrid machine learning/deep learning…

Longitudinal modified treatment policies (LMTP) have been recently developed as a novel method to define and estimate causal parameters that depend on the natural value of treatment. LMTPs represent an important advancement in causal…

统计方法学 · 统计学 2025-02-06 Iván Díaz , Katherine L Hoffman , Nima S. Hejazi

COVID-19 data released by public health authorities features the presence of notable time-delays, corresponding to the difference between actual time of infection and identification of infection. These delays have several causes, including…

动力系统 · 数学 2021-11-29 Nicola Guglielmi , Elisa Iacomini , Alex Viguerie

The optimal moment to start renal replacement therapy in a patient with acute kidney injury (AKI) remains a challenging problem in intensive care nephrology. Multiple randomised controlled trials have tried to answer this question, but…

The possibility to use widespread and simple chest X-ray (CXR) imaging for early screening of COVID-19 patients is attracting much interest from both the clinical and the AI community. In this study we provide insights and also raise…

图像与视频处理 · 电气工程与系统科学 2020-10-20 Enzo Tartaglione , Carlo Alberto Barbano , Claudio Berzovini , Marco Calandri , Marco Grangetto

Cardiovascular disease and chronic kidney disease are major complications of diabetes, leading to high morbidity and mortality. Early detection of these conditions is critical, yet traditional diagnostic markers often lack sensitivity in…

其他定量生物学 · 定量生物学 2025-10-20 Syed Ibad Hasnain