相关论文: BARTSmiles: Generative Masked Language Models for …

Neuroscience research has made immense progress over the last decade, but our understanding of the brain remains fragmented and piecemeal: the dream of probing an arbitrary brain region and automatically reading out the information encoded…

Representation learning for text via pretraining a language model on a large corpus has become a standard starting point for building NLP systems. This approach stands in contrast to autoencoders, also trained on raw text, but with the…

Foundation models have transformed vision and language by learning general-purpose representations from large-scale unlabeled data, yet 3D medical imaging lacks analogous approaches. Existing self-supervised methods rely on low-level…

In reasoning tasks, even a minor error can cascade into inaccurate results, leading to suboptimal performance of large language models in such domains. Earlier fine-tuning approaches sought to mitigate this by leveraging more precise…

As the deep learning revolution marches on, self-supervised learning has garnered increasing attention in recent years thanks to its remarkable representation learning ability and the low dependence on labeled data. Among these varied…

Activity cliffs, which refer to pairs of molecules that are structurally similar but show significant differences in their potency, can lead to model representation collapse and make the model challenging to distinguish them. Our research…

Recent Self-Supervised Learning (SSL) methods are able to learn feature representations that are invariant to different data augmentations, which can then be transferred to downstream tasks of interest. However, different downstream tasks…

Generative models in molecular design tend to be richly parameterized, data-hungry neural models, as they must create complex structured objects as outputs. Estimating such models from data may be challenging due to the lack of sufficient…

Natural language understanding has recently seen a surge of progress with the use of sentence encoders like ELMo (Peters et al., 2018a) and BERT (Devlin et al., 2019) which are pretrained on variants of language modeling. We conduct the…

Masked Image Modeling (MIM) achieves outstanding success in self-supervised representation learning. Unfortunately, MIM models typically have huge computational burden and slow learning process, which is an inevitable obstacle for their…

Machine reading comprehension (MRC) is a challenging natural language processing (NLP) task. Recently, the emergence of pre-trained models (PTM) has brought this research field into a new era, in which the training objective plays a key…

Masked language modeling (MLM) is the standard objective for training protein language models, typically implemented by randomly masking individual residues at a fixed rate (e.g., 15%). This practice implicitly assumes that all sequence…

Recently, pre-trained language models mostly follow the pre-train-then-fine-tuning paradigm and have achieved great performance on various downstream tasks. However, since the pre-training stage is typically task-agnostic and the…

Despite recent progress in time-series foundation models, challenges persist in improving representation learning and adapting to diverse downstream tasks. We introduce a General Time-series Model (GTM), which advances representation…

Paraphrase generation is a long-standing problem and serves an essential role in many natural language processing problems. Despite some encouraging results, recent methods either confront the problem of favoring generic utterance or need…

While the Self-Attention mechanism in the Transformer model has proven to be effective in many domains, we observe that it is less effective in more diverse settings (e.g. multimodality) due to the varying granularity of each token and the…

Word ordering is a constrained language generation task taking unordered words as input. Existing work uses linear models and neural networks for the task, yet pre-trained language models have not been studied in word ordering, let alone…

Recent works have shown that Large Language Models (LLMs) could empower traditional neuro-symbolic models via programming capabilities to translate language into module descriptions, thus achieving strong visual reasoning results while…

Transformer architectures show significant promise for natural language processing. Given that a single pretrained model can be fine-tuned to perform well on many different tasks, these networks appear to extract generally useful linguistic…

A plethora of protein language models have been released in recent years. Yet comparatively little work has addressed how to best sample from them to optimize desired biological properties. We fill this gap by proposing a flexible,…