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相关论文: Joint Cryo-ET Alignment and Reconstruction with Ne…

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In this paper, we present an algorithm for effectively reconstructing an object from a set of its tomographic projections without any knowledge of the viewing directions or any prior structural information, in the presence of pathological…

图像与视频处理 · 电气工程与系统科学 2019-06-12 Ritwick Chaudhry , Arunabh Ghosh , Ajit Rajwade

Discovering the 3D atomic structure of molecules such as proteins and viruses is a fundamental research problem in biology and medicine. Electron Cryomicroscopy (Cryo-EM) is a promising vision-based technique for structure estimation which…

计算机视觉与模式识别 · 计算机科学 2016-11-18 Marcus A. Brubaker , Ali Punjani , David J. Fleet

Cryo-Electron Microscopy (cryo-EM) has emerged as a key technology to determine the structure of proteins, particularly large protein complexes and assemblies in recent years. A key challenge in cryo-EM data analysis is to automatically…

生物大分子 · 定量生物学 2023-04-04 Nabin Giri , Raj S. Roy , Jianlin Cheng

The growing role of data-driven approaches to scientific discovery has unveiled a large class of models that involve latent transformations with a rigid algebraic constraint. Three-dimensional molecule reconstruction in Cryo-Electron…

信息论 · 计算机科学 2019-06-04 Amelia Perry , Jonathan Weed , Afonso S. Bandeira , Philippe Rigollet , Amit Singer

Cryo-electron microscopy (cryo-EM) has become a central tool for high-resolution structural biology, yet the massive scale of datasets (often exceeding 100k particle images) renders 3D reconstruction both computationally expensive and…

计算机视觉与模式识别 · 计算机科学 2025-10-03 Huaizhi Qu , Xiao Wang , Gengwei Zhang , Jie Peng , Tianlong Chen

As a critical modality for structural biology, cryogenic electron microscopy (cryo-EM) facilitates the determination of macromolecular structures at near-atomic resolution. The core computational task in single-particle cryo-EM is to…

图像与视频处理 · 电气工程与系统科学 2026-05-04 Suyi Chen , Haibin Ling

Cryo-electron microscopy (cryo-EM) is an experimental technique for protein structure determination that images an ensemble of macromolecules in near-physiological contexts. While recent advances enable the reconstruction of dynamic…

We propose a method to reconstruct the 3-D molecular structure from micrographs collected at just one sample tilt angle in the random conical tilt scheme in cryo-electron microscopy. Our method uses autocorrelation analysis on the…

数据分析、统计与概率 · 物理学 2021-01-12 Ti-Yen Lan , Nicolas Boumal , Amit Singer

Differential phase-contrast computed tomography (DPC-CT) is a powerful analysis tool for soft-tissue and low-atomic-number samples. Limited by the implementation conditions, DPC-CT with incomplete projections happens quite often.…

医学物理 · 物理学 2020-07-01 Jianbing Dong , Jian Fu , Zhao He

Accurate pose estimation and shift correction are key challenges in cryo-EM due to the very low SNR, which directly impacts the fidelity of 3D reconstructions. We present an approach for pose estimation in cryo-EM that leverages…

计算机视觉与模式识别 · 计算机科学 2025-07-22 Kaishva Chintan Shah , Virajith Boddapati , Karthik S. Gurumoorthy , Sandip Kaledhonkar , Ajit Rajwade

Shape retrieval and alignment are a promising avenue towards turning 3D scans into lightweight CAD representations that can be used for content creation such as mobile or AR/VR gaming scenarios. Unfortunately, CAD model retrieval is limited…

计算机视觉与模式识别 · 计算机科学 2020-07-24 Vladislav Ishimtsev , Alexey Bokhovkin , Alexey Artemov , Savva Ignatyev , Matthias Niessner , Denis Zorin , Evgeny Burnaev

Cryo-EM is an increasingly popular method for determining the atomic resolution 3D structure of macromolecular complexes (eg, proteins) from noisy 2D images captured by an electron microscope. The computational task is to reconstruct the 3D…

计算机视觉与模式识别 · 计算机科学 2024-10-04 Shayan Shekarforoush , David B. Lindell , Marcus A. Brubaker , David J. Fleet

The computational pipelines of single-particle cryo-electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET) include an early particle-picking stage, in which a micrograph or tomogram is scanned to extract candidate particles,…

信号处理 · 电气工程与系统科学 2026-04-14 Amnon Balanov , Alon Zabatani , Tamir Bendory

The reconstruction of 3D objects from brain signals has gained significant attention in brain-computer interface (BCI) research. Current research predominantly utilizes functional magnetic resonance imaging (fMRI) for 3D reconstruction…

图形学 · 计算机科学 2025-05-06 Xia Deng , Shen Chen , Jiale Zhou , Lei Li

Motion during acquisition of a set of projections can lead to significant motion artifacts in computed tomography reconstructions despite fast acquisition of individual views. In cases such as cardiac imaging, motion may be unavoidable and…

图像与视频处理 · 电气工程与系统科学 2022-01-19 Kunal Gupta , Brendan Colvert , Francisco Contijoch

Deformable medical image registration is an essential task in computer-assisted interventions. This problem is particularly relevant to oncological treatments, where precise image alignment is necessary for tracking tumor growth, assessing…

计算机视觉与模式识别 · 计算机科学 2025-06-04 Stefano Fogarollo , Gregor Laimer , Reto Bale , Matthias Harders

Cryo-electron microscopy (cryo-EM) is a technique for reconstructing the 3-dimensional (3D) structure of biomolecules (especially large protein complexes and molecular assemblies). As the resolution increases to the near-atomic scale,…

计算机视觉与模式识别 · 计算机科学 2023-08-08 Weijie Chen , Xinyan Wang , Yuhang Wang

Reconstruction of the shape and motion of humans from RGB-D is a challenging problem, receiving much attention in recent years. Recent approaches for full-body reconstruction use a statistic shape model, which is built upon accurate…

计算机视觉与模式识别 · 计算机科学 2018-07-10 Ryosuke Kimura , Akihiko Sayo , Fabian Lorenzo Dayrit , Yuta Nakashima , Hiroshi Kawasaki , Ambrosio Blanco , Katsushi Ikeuchi

Cellular Electron Cryo-Tomography (CECT) is a powerful 3D imaging tool for studying the native structure and organization of macromolecules inside single cells. For systematic recognition and recovery of macromolecular structures captured…

计算机视觉与模式识别 · 计算机科学 2018-07-04 Chang Liu , Xiangrui Zeng , Kaiwen Wang , Qiang Guo , Min Xu

Reconstructing the 3D shape of a deformable environment from the information captured by a moving depth camera is highly relevant to surgery. The underlying challenge is the fact that simultaneously estimating camera motion and tissue…

计算机视觉与模式识别 · 计算机科学 2024-08-09 Guido Caccianiga , Julian Nubert , Cesar Cadena , Marco Hutter , Katherine J. Kuchenbecker