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相关论文: Extending the Neural Additive Model for Survival A…

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In the context of survival analysis, data-driven neural network-based methods have been developed to model complex covariate effects. While these methods may provide better predictive performance than regression-based approaches, not all…

机器学习 · 统计学 2024-04-23 Jesse Islam , Maxime Turgeon , Robert Sladek , Sahir Bhatnagar

Accurate prediction of disease trajectories is critical for early identification and timely treatment of patients at risk. Conventional methods in survival analysis are often constrained by strong parametric assumptions and limited in their…

机器学习 · 计算机科学 2018-11-28 Daniel Jarrett , Jinsung Yoon , Mihaela van der Schaar

We present neural frailty machine (NFM), a powerful and flexible neural modeling framework for survival regressions. The NFM framework utilizes the classical idea of multiplicative frailty in survival analysis to capture unobserved…

机器学习 · 计算机科学 2023-10-05 Ruofan Wu , Jiawei Qiao , Mingzhe Wu , Wen Yu , Ming Zheng , Tengfei Liu , Tianyi Zhang , Weiqiang Wang

Cox proportional hazards model is one of the most popular models in biomedical data analysis. There have been continuing efforts to improve the flexibility of such models for complex signal detection, for example, via additive functions.…

统计方法学 · 统计学 2022-05-25 Boyi Guo , Nengjun Yi

Deep learning methods exhibit promising performance for predictive modeling in healthcare, but two important challenges remain: -Data insufficiency:Often in healthcare predictive modeling, the sample size is insufficient for deep learning…

机器学习 · 计算机科学 2017-04-04 Edward Choi , Mohammad Taha Bahadori , Le Song , Walter F. Stewart , Jimeng Sun

Clinical risk prediction using electronic health records (EHRs) is vital to facilitate timely interventions and clinical decision support. However, modeling heterogeneous and irregular temporal EHR data presents significant challenges. We…

机器学习 · 计算机科学 2025-11-04 Kun-Wei Lin , Yu-Chen Kuo , Hsin-Yao Wang , Yi-Ju Tseng

Lung cancer is a major cause of cancer-related deaths, and early diagnosis and treatment are crucial for improving patients' survival outcomes. In this paper, we propose to employ convolutional neural networks to model the non-linear…

图像与视频处理 · 电气工程与系统科学 2024-08-20 Xiawei Wang , James Sharpnack , Thomas C. M. Lee

Deployment of machine learning models in real high-risk settings (e.g. healthcare) often depends not only on the model's accuracy but also on its fairness, robustness, and interpretability. Generalized Additive Models (GAMs) are a class of…

机器学习 · 计算机科学 2022-03-17 Chun-Hao Chang , Rich Caruana , Anna Goldenberg

Neural additive model (NAM) is a recently proposed explainable artificial intelligence (XAI) method that utilizes neural network-based architectures. Given the advantages of neural networks, NAMs provide intuitive explanations for their…

机器学习 · 计算机科学 2024-11-12 Hoki Kim , Jinseong Park , Yujin Choi , Seungyun Lee , Jaewook Lee

We propose a versatile framework for survival analysis that combines advanced concepts from statistics with deep learning. The presented framework is based on piecewise exponential models and thereby supports various survival tasks, such as…

An accurate model of patient-specific kidney graft survival distributions can help to improve shared-decision making in the treatment and care of patients. In this paper, we propose a deep learning method that directly models the survival…

机器学习 · 计算机科学 2017-05-30 Margaux Luck , Tristan Sylvain , Héloïse Cardinal , Andrea Lodi , Yoshua Bengio

Cancer clinics capture disease data at various scales, from genetic to organ level. Current bioinformatic methods struggle to handle the heterogeneous nature of this data, especially with missing modalities. We propose PARADIGM, a Graph…

细胞行为 · 定量生物学 2024-11-22 Asim Waqas , Aakash Tripathi , Paul Stewart , Mia Naeini , Matthew B. Schabath , Ghulam Rasool

Survival analysis aims to model how covariates and time jointly shape the time-to-event distribution under right censoring. Classical methods such as the Cox model and generalised additive models (GAMs) require interactions and time-varying…

机器学习 · 统计学 2026-05-26 Stelios Boulitsakis Logothetis , Angela Wood , Pietro Liò

The Cox proportional hazards model is a canonical method in survival analysis for prediction of the life expectancy of a patient given clinical or genetic covariates -- it is a linear model in its original form. In recent years, several…

Generalized additive models (GAMs) have long been a powerful white-box tool for the intelligible analysis of tabular data, revealing the influence of each feature on the model predictions. Despite the success of neural networks (NNs) in…

机器学习 · 计算机科学 2024-10-08 Guangzhi Xiong , Sanchit Sinha , Aidong Zhang

In survival analysis, Cox model is widely used for most clinical trial data. Alternatives include the additive hazard model, the accelerated failure time (AFT) model and a more general transformation model. All these models assume that the…

统计方法学 · 统计学 2016-03-24 Cheng Zheng , Ying Qing Chen

Computational prediction of in-hospital mortality in the setting of an intensive care unit can help clinical practitioners to guide care and make early decisions for interventions. As clinical data are complex and varied in their structure…

机器学习 · 计算机科学 2020-12-29 Tingyi Wanyan , Hossein Honarvar , Ariful Azad , Ying Ding , Benjamin S. Glicksberg

This paper considers robust modeling of the survival time for cancer patients. Accurate prediction can be helpful for developing therapeutic and care strategies. We propose a unified Expectation-Maximization approach combined with the…

统计方法学 · 统计学 2019-12-23 Yi Li , Muxuan Liang , Lu Mao , Sijian Wang

Energy consumption from the selection, training, and deployment of deep learning models has seen a significant uptick recently. This work aims to facilitate the design of energy-efficient deep learning models that require less computational…

机器学习 · 计算机科学 2024-03-25 Pedram Bakhtiarifard , Christian Igel , Raghavendra Selvan

Traditional survival models often rely on restrictive assumptions such as proportional hazards or instantaneous effects of time-varying covariates on the hazard function, which limit their applicability in real-world settings. We consider…

统计方法学 · 统计学 2025-05-30 Bingqing Hu , Bin Nan