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Medical imaging plays a vital role in modern diagnostics and treatment. The temporal nature of disease or treatment progression often results in longitudinal data. Due to the cost and potential harm, acquiring large medical datasets…

Our objective is to evaluate the efficacy of methods that use deep learning (DL) for the automatic fine-grained segmentation of optical coherence tomography (OCT) images of the retina. OCT images from 10 patients with mild non-proliferative…

We propose a Noise Entangled GAN (NE-GAN) for simulating low-dose computed tomography (CT) images from a higher dose CT image. First, we present two schemes to generate a clean CT image and a noise image from the high-dose CT image. Then,…

SARS-CoV-2, also known as COVID-19 or Coronavirus, is a viral contagious disease that is infected by a novel coronavirus, and has been rapidly spreading across the globe. It is very important to test and isolate people to reduce spread, and…

Deep learning-based virtual staining was developed to introduce image contrast to label-free tissue sections, digitally matching the histological staining, which is time-consuming, labor-intensive, and destructive to tissue. Standard…

Cardiovascular diseases (CVD) are the leading cause of death globally. Non-invasive, cost-effective imaging techniques play a crucial role in early detection and prevention of CVD. Optical coherence tomography (OCT) has gained recognition…

Computed Tomography (CT) plays a pivotal role in medical diagnosis; however, variability across reconstruction kernels hinders data-driven approaches, such as deep learning models, from achieving reliable and generalized performance. To…

Biopsies are the gold standard for breast cancer diagnosis. This task can be improved by the use of Computer Aided Diagnosis (CAD) systems, reducing the time of diagnosis and reducing the inter and intra-observer variability. The advances…

Background: Coronary angiography (CAG) is a cornerstone imaging modality for assessing coronary artery disease and guiding interventional treatment decisions. However, in real-world clinical settings, angiographic images are often…

Due to its noninvasive character, optical coherence tomography (OCT) has become a popular diagnostic method in clinical settings. However, the low-coherence interferometric imaging procedure is inevitably contaminated by heavy speckle…

Doppler holography is an emerging retinal imaging technique that captures the dynamic behavior of blood flow with high temporal resolution, enabling quantitative assessment of retinal hemodynamics. This requires accurate segmentation of…

Histopathologic Images (HI) are the gold standard for evaluation of some tumors. However, the analysis of such images is challenging even for experienced pathologists, resulting in problems of inter and intra observer. Besides that, the…

Recent studies suggest that early stages of diabetic retinopathy (DR) can be diagnosed by monitoring vascular changes in the deep vascular complex. In this work, we investigate a novel method for automated DR grading based on optical…

The evaluation of obstructions (stenosis) in coronary arteries is currently done by a physician's visual assessment of coronary angiography video sequences. It is laborious, and can be susceptible to interobserver variation. Prior studies…

Despite recent advances in diagnosis and treatment, atherosclerotic coronary artery diseases remain a leading cause of death worldwide. Various imaging modalities and metrics can detect lesions and predict patients at risk; however,…

Deep learning methods for classifying medical images have demonstrated impressive accuracy in a wide range of tasks but often these models are hard to interpret, limiting their applicability in clinical practice. In this work we introduce a…

Knowledge of what spatial elements of medical images deep learning methods use as evidence is important for model interpretability, trustiness, and validation. There is a lack of such techniques for models in regression tasks. We propose a…

Texture synthesis is a fundamental task in computer vision, whose goal is to generate visually realistic and structurally coherent textures for a wide range of applications, from graphics to scientific simulations. While traditional methods…

Ultrasound imaging makes use of backscattering of waves during their interaction with scatterers present in biological tissues. Simulation of synthetic ultrasound images is a challenging problem on account of inability to accurately model…

Coronary CT angiography (CCTA) has established its role as a non-invasive modality for the diagnosis of coronary artery disease (CAD). The CAD-Reporting and Data System (CAD-RADS) has been developed to standardize communication and aid in…