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The advent of large scale, high-throughput genomic screening has introduced a wide range of tests for diagnostic purposes. Prominent among them are tests using miRNA expression levels. Genomics and proteomics now provide expression levels…

基因组学 · 定量生物学 2016-11-08 Neerja Garikipati

Model merging combines fine-tuned checkpoints into a single multi-task model without retraining. Existing methods - such as task arithmetic, model soups, TIES, and DARE - are computationally efficient and empirically successful, but rely on…

机器学习 · 计算机科学 2026-05-29 Bethan Evans , Benjamin Etheridge , Stephen Roberts , Jared Tanner

Large language models (LLMs) have rapidly evolved from text generators into powerful problem solvers. Yet, many open tasks demand critical thinking, multi-source, and verifiable outputs, which are beyond single-shot prompting or standard…

Radiotherapy (RT) planning is complex, subjective, and time-intensive. Advances with artificial intelligence (AI) promise to improve its precision and efficiency, but progress is often limited by the scarcity of large, standardized…

This paper explores the application of Human-in-the-Loop (HITL) strategies in training machine learning models in the medical domain. In this case a doctor-in-the-loop approach is proposed to leverage human expertise in dealing with large…

Context: The software development industry is rapidly adopting machine learning for transitioning modern day software systems towards highly intelligent and self-learning systems. However, the full potential of machine learning for…

软件工程 · 计算机科学 2021-10-18 Saad Shafiq , Atif Mashkoor , Christoph Mayr-Dorn , Alexander Egyed

We describe the experimental methodology developed and employed in a series of experiments within the Defense Advanced Research Projects Agency (DARPA) Conflict Modeling, Planning, and Outcomes Exploration (COMPOEX) Program. The primary…

计算机与社会 · 计算机科学 2015-12-29 Alexander Kott , Jeff Hansberger , Edward Waltz , Peter Corpac

Teaching machines to read natural language documents remains an elusive challenge. Machine reading systems can be tested on their ability to answer questions posed on the contents of documents that they have seen, but until now large scale…

Medical imaging is an essential tool for diagnosing various healthcare diseases and conditions. However, analyzing medical images is a complex and time-consuming task that requires expertise and experience. This article aims to design a…

图像与视频处理 · 电气工程与系统科学 2023-05-15 Ayyub Alzahem , Shahid Latif , Wadii Boulila , Anis Koubaa

Cancer analysis and prediction is the utmost important research field for well-being of humankind. The Cancer data are analyzed and predicted using machine learning algorithms. Most of the researcher claims the accuracy of the predicted…

机器学习 · 计算机科学 2019-03-19 Ripon Patgiri , Sabuzima Nayak , Tanya Akutota , Bishal Paul

Deep learning methods, in particular convolutional neural networks, have emerged as a powerful tool in medical image computing tasks. While these complex models provide excellent performance, their black-box nature may hinder real-world…

图像与视频处理 · 电气工程与系统科学 2022-10-18 Yuzhe Lu , Adam Perer

A fundamental trade-off between effectiveness and efficiency needs to be balanced when designing an online question answering system. Effectiveness comes from sophisticated functions such as extractive machine reading comprehension (MRC),…

计算与语言 · 计算机科学 2019-08-14 Ming Yan , Jiangnan Xia , Chen Wu , Bin Bi , Zhongzhou Zhao , Ji Zhang , Luo Si , Rui Wang , Wei Wang , Haiqing Chen

Mechanical models for tumor growth have been used extensively in recent years for the analysis of medical observations and for the prediction of cancer evolution based on imaging analysis. This work deals with the numerical approximation of…

数值分析 · 数学 2015-04-24 Konstantina Trivisa , Franziska Weber

We present multiscale models of cancer tumor invasion with components at the molecular, cellular, and tissue levels. We provide biological justifications for the model components, present computational results from the model, and discuss…

定量方法 · 定量生物学 2023-02-14 Bruce P. Ayati , Glenn F. Webb , Alexander R. A. Anderson

State machine formalisms equipped with hierarchy and parallelism allow to compactly model complex system behaviours. Such models can then be transformed into executable code or inputs for model-based testing and verification techniques.…

软件工程 · 计算机科学 2017-10-24 Xavier Devroey , Gilles Perrouin , Maxime Cordy , Axel Legay , Pierre-Yves Schobbens , Patrick Heymans

Model merging is to combine fine-tuned models derived from multiple domains, with the intent of enhancing the model's proficiency across various domains. The principal concern is the resolution of parameter conflicts. A substantial amount…

计算与语言 · 计算机科学 2024-03-06 Yaochen Zhu , Rui Xia , Jiajun Zhang

Objectives: To assess evaluative methodologies for comparative measurements of test sensitivity in clinical mammographic screening trials of computer-aided detection (CAD) technologies. Materials and Methods: This meta-analysis was…

医学物理 · 物理学 2013-02-07 Jacob Levman

Nowadays new technologies, and especially artificial intelligence, are more and more established in our society. Big data analysis and machine learning, two sub-fields of artificial intelligence, are at the core of many recent breakthroughs…

机器学习 · 统计学 2021-06-22 Antonio Sutera

Large Language Models (LLMs) are increasingly utilized in scientific research assessment, particularly in automated paper review. However, existing LLM-based review systems face significant challenges, including limited domain expertise,…

计算与语言 · 计算机科学 2025-03-12 Minjun Zhu , Yixuan Weng , Linyi Yang , Yue Zhang

Effective preoperative planning requires accurate algorithms for segmenting anatomical structures across diverse datasets, but traditional models struggle with generalization. This study presents a novel machine learning methodology to…