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Time-to-event modelling, known as survival analysis, differs from standard regression as it addresses censoring in patients who do not experience the event of interest. Despite competitive performances in tackling this problem, machine…

机器学习 · 计算机科学 2023-05-12 Vincent Jeanselme , Chang Ho Yoon , Brian Tom , Jessica Barrett

Causal discovery is becoming a key part in medical AI research. These methods can enhance healthcare by identifying causal links between biomarkers, demographics, treatments and outcomes. They can aid medical professionals in choosing more…

Lung cancer, a severe form of malignant tumor that originates in the tissues of the lungs, can be fatal if not detected in its early stages. It ranks among the top causes of cancer-related mortality worldwide. Detecting lung cancer manually…

计算机视觉与模式识别 · 计算机科学 2025-04-22 Santanu Roy , Shweta Singh , Palak Sahu , Ashvath Suresh , Debashish Das

In this paper, we examine the strength of deep learning technique for diagnosing lung cancer on medical image analysis problem. Convolutional neural networks (CNNs) models become popular among the pattern recognition and computer vision…

计算机视觉与模式识别 · 计算机科学 2018-04-24 Mehdi Fatan Serj , Bahram Lavi , Gabriela Hoff , Domenec Puig Valls

Advances in healthcare research have significantly enhanced our understanding of disease mechanisms, diagnostic precision, and therapeutic options. Yet, lung cancer remains one of the leading causes of cancer-related mortality worldwide due…

计算机视觉与模式识别 · 计算机科学 2025-06-06 Sugandha Saxena , S. N. Prasad , Ashwin M Polnaya , Shweta Agarwala

Lung and colon cancer are serious worldwide health challenges that require early and precise identification to reduce mortality risks. However, diagnosis, which is mostly dependent on histopathologists' competence, presents difficulties and…

图像与视频处理 · 电气工程与系统科学 2024-05-15 Mukaffi Bin Moin , Fatema Tuj Johora Faria , Swarnajit Saha , Busra Kamal Rafa , Mohammad Shafiul Alam

Aim: Early detection and correct diagnosis of lung cancer are the most important steps in improving patient outcome. This study aims to assess which deep learning models perform best in lung cancer diagnosis. Methods: Non-small cell lung…

计算机视觉与模式识别 · 计算机科学 2018-03-16 Zhang Li , Zheyu Hu , Jiaolong Xu , Tao Tan , Hui Chen , Zhi Duan , Ping Liu , Jun Tang , Guoping Cai , Quchang Ouyang , Yuling Tang , Geert Litjens , Qiang Li

Multimodal survival methods combining gigapixel histology whole-slide images (WSIs) and transcriptomic profiles are particularly promising for patient prognostication and stratification. Current approaches involve tokenizing the WSIs into…

计算机视觉与模式识别 · 计算机科学 2024-07-02 Andrew H. Song , Richard J. Chen , Guillaume Jaume , Anurag J. Vaidya , Alexander S. Baras , Faisal Mahmood

Survival analysis consists of studying the elapsed time until an event of interest, such as the death or recovery of a patient in medical studies. This work explores the potential of neural networks in survival analysis from clinical and…

统计理论 · 数学 2021-05-19 Mathilde Sautreuil , Sarah Lemler , Paul-Henry Cournède

Despite significant research efforts and advancements, cancer remains a leading cause of mortality. Early cancer prediction has become a crucial focus in cancer research to streamline patient care and improve treatment outcomes. Manual…

计算机视觉与模式识别 · 计算机科学 2024-08-19 Samta Rani , Tanvir Ahmad , Sarfaraz Masood , Chandni Saxena

Clinical data elements (CDEs) (e.g., age, smoking history), blood markers and chest computed tomography (CT) structural features have been regarded as effective means for assessing lung cancer risk. These independent variables can provide…

图像与视频处理 · 电气工程与系统科学 2021-02-11 Riqiang Gao , Yucheng Tang , Kaiwen Xu , Michael N. Kammer , Sanja L. Antic , Steve Deppen , Kim L. Sandler , Pierre P. Massion , Yuankai Huo , Bennett A. Landman

Genomics, especially multi-omics, has made precision medicine feasible. The completion and publicly accessible multi-omics resource with clinical outcome, such as The Cancer Genome Atlas (TCGA) is a great test bed for developing…

基因组学 · 定量生物学 2020-08-31 Lana X Garmire

Lung cancer is a leading cause of cancer-related deaths globally, where early detection and accurate diagnosis are critical for improving survival rates. While deep learning, particularly convolutional neural networks (CNNs), has…

图像与视频处理 · 电气工程与系统科学 2025-05-15 Sadman Sakib Alif , Nasim Anzum Promise , Fiaz Al Abid , Aniqua Nusrat Zereen

Lung nodule malignancy prediction has been enhanced by advanced deep-learning techniques and effective tricks. Nevertheless, current methods are mainly trained with cross-entropy loss using one-hot categorical labels, which results in…

计算机视觉与模式识别 · 计算机科学 2023-10-03 Yiming Lei , Zilong Li , Yan Shen , Junping Zhang , Hongming Shan

Background: Stratifying cancer patients according to risk of relapse can personalize their care. In this work, we provide an answer to the following research question: How to utilize machine learning to estimate probability of relapse in…

Integrating cross-department multi-modal data (e.g., radiological, pathological, genomic, and clinical data) is ubiquitous in brain cancer diagnosis and survival prediction. To date, such an integration is typically conducted by human…

Artificial intelligence (AI) has brought tremendous impacts on biomedical sciences from academic researches to clinical applications, such as in biomarkers' detection and diagnosis, optimization of treatment, and identification of new…

定量方法 · 定量生物学 2023-03-14 Yu-Jia An , Sheng-Chen Bai , Lin Cheng , Xiao-Guang Li , Cheng-en Wang , Xiao-Dong Han , Gang Su , Shi-Ju Ran , Cong Wang

Deep learning-based computer-aided diagnosis has achieved unprecedented performance in breast cancer detection. However, most approaches are computationally intensive, which impedes their broader dissemination in real-world applications. In…

图像与视频处理 · 电气工程与系统科学 2022-01-14 Jiaqiao Shi , Aleksandar Vakanski , Min Xian , Jianrui Ding , Chunping Ning

Survival analysis plays a vital role in making clinical decisions. However, the models currently in use are often difficult to interpret, which reduces their usefulness in clinical settings. Prototype learning presents a potential solution,…

计算机视觉与模式识别 · 计算机科学 2025-10-08 Shuo Jiang , Zhuwen Chen , Liaoman Xu , Yanming Zhu , Changmiao Wang , Jiong Zhang , Feiwei Qin , Yifei Chen , Zhu Zhu

The introduction of lung cancer screening programs will produce an unprecedented amount of chest CT scans in the near future, which radiologists will have to read in order to decide on a patient follow-up strategy. According to the current…