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相关论文: Cell tracking for live-cell microscopy using an ac…

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Conventional multi-stage cell tracking approaches rely heavily on detection or segmentation in each frame as a prerequisite, requiring substantial resources for high-quality segmentation masks and increasing the overall prediction time. To…

图像与视频处理 · 电气工程与系统科学 2025-10-14 Yaxuan Song , Jianan Fan , Heng Huang , Mei Chen , Weidong Cai

Cell counting in microscopy images is vital in medicine and biology but extremely tedious and time-consuming to perform manually. While automated methods have advanced in recent years, state-of-the-art approaches tend to increasingly…

计算机视觉与模式识别 · 计算机科学 2025-03-19 Zixuan Zheng , Yilei Shi , Chunlei Li , Jingliang Hu , Xiao Xiang Zhu , Lichao Mou

We propose a novel approach to automatically tracking cell populations in time-lapse images. To account for cell occlusions and overlaps, we introduce a robust method that generates an over-complete set of competing detection hypotheses. We…

计算机视觉与模式识别 · 计算机科学 2016-01-27 Engin Türetken , Xinchao Wang , Carlos Becker , Carsten Haubold , Pascal Fua

Quantitative analysis of the dynamics of tiny cellular and sub-cellular structures, known as particles, in time-lapse cell microscopy sequences requires the development of a reliable multi-target tracking method capable of tracking numerous…

计算机视觉与模式识别 · 计算机科学 2015-07-24 Seyed Hamid Rezatofighi , Stephen Gould , Ba Tuong Vo , Ba-Ngu Vo , Katarina Mele , Richard Hartley

A systematic analysis of the cell behavior requires automated approaches for cell segmentation and tracking. While deep learning has been successfully applied for the task of cell segmentation, there are few approaches for simultaneous cell…

计算机视觉与模式识别 · 计算机科学 2024-10-28 Katharina Löffler , Ralf Mikut

Cell detection and tracking are paramount for bio-analysis. Recent approaches rely on the tracking-by-model evolution paradigm, which usually consists of training end-to-end deep learning models to detect and track the cells on the frames…

计算机视觉与模式识别 · 计算机科学 2023-10-12 Lucas N. Kirsten , Cláudio R. Jung

High-throughput screening using cell images is an efficient method for screening new candidates for pharmaceutical drugs. To complete the screening process, it is essential to have an efficient process for analyzing cell images. This paper…

计算机视觉与模式识别 · 计算机科学 2024-02-28 Mizuki Fukasawa , Tomokazu Fukuda , Takuya Akashi

Tracking cells in time-lapse videos is an essential technique for monitoring cell population dynamics at a single-cell level. Current methods for cell tracking are developed on videos with mostly single, constant signals and do not detect…

计算机视觉与模式识别 · 计算机科学 2025-12-17 Florian Bürger , Martim Dias Gomes , Nica Gutu , Adrián E. Granada , Noémie Moreau , Katarzyna Bozek

Cells are the fundamental unit of biological organization, and identifying them in imaging data - cell segmentation - is a critical task for various cellular imaging experiments. While deep learning methods have led to substantial progress…

Increasing data set sizes of 3D microscopy imaging experiments demand for an automation of segmentation processes to be able to extract meaningful biomedical information. Due to the shortage of annotated 3D image data that can be used for…

图像与视频处理 · 电气工程与系统科学 2022-02-02 Dennis Eschweiler , Richard S. Smith , Johannes Stegmaier

This paper presents a method for time-lapse 3D cell analysis. Specifically, we consider the problem of accurately localizing and quantitatively analyzing sub-cellular features, and for tracking individual cells from time-lapse 3D confocal…

计算机视觉与模式识别 · 计算机科学 2022-08-18 Jiaxiang Jiang , Amil Khan , S. Shailja , Samuel A. Belteton , Michael Goebel , Daniel B. Szymanski , B. S. Manjunath

Live-cell microscopy allows to go beyond measuring average features of cellular populations to observe, quantify and explain biological heterogeneity. Deep Learning-based instance segmentation and cell tracking form the gold standard…

定量方法 · 定量生物学 2024-08-09 Richard D. Paul , Johannes Seiffarth , Hanno Scharr , Katharina Nöh

Cell segmentation and tracking in microscopy images are of great significance to new discoveries in biology and medicine. In this study, we propose a novel approach to combine cell segmentation and cell tracking into a unified end-to-end…

计算机视觉与模式识别 · 计算机科学 2021-02-23 Yuqian Chen , Yang Song , Chaoyi Zhang , Fan Zhang , Lauren O'Donnell , Wojciech Chrzanowski , Weidong Cai

Cell-cell adhesion plays a vital role in the development and maintenance of multicellular organisms. One of its functions is regulation of cell migration, such as occurs, e.g. during embryogenesis or in cancer. In this work, we develop a…

组织与器官 · 定量生物学 2024-03-08 Anna Zhigun , Mabel Lizzy Rajendran

3D fluorescence microscopy of living organisms has increasingly become an essential and powerful tool in biomedical research and diagnosis. An exploding amount of imaging data has been collected, whereas efficient and effective…

图像与视频处理 · 电气工程与系统科学 2019-11-28 Yang Jiao , Mo Weng , Mei Yang

Single-cell trajectory analysis aims to reconstruct the biological developmental processes of cells as they evolve over time, leveraging temporal correlations in gene expression. During cellular development, gene expression patterns…

应用统计 · 统计学 2026-03-30 Junhao Zhu , Kevin Zhang , Zhaolei Zhang , Dehan Kong

Recent trends in cell segmentation have shifted towards universal models to handle diverse cell morphologies and imaging modalities. However, for continuously emerging cell types and imaging techniques, these models still require hundreds…

计算机视觉与模式识别 · 计算机科学 2024-12-03 Peilin Zhou , Bo Du , Yongchao Xu

The automated segmentation and tracking of macrophages during their migration are challenging tasks due to their dynamically changing shapes and motions. This paper proposes a new algorithm to achieve automatic cell tracking in time-lapse…

图像与视频处理 · 电气工程与系统科学 2023-01-03 Seol Ah Park , Tamara Sipka , Zuzana Kriva , George Lutfalla , Mai Nguyen-Chi , Karol Mikula

The mother machine is a popular microfluidic device that allows long-term time-lapse imaging of thousands of cells in parallel by microscopy. It has become a valuable tool for single-cell level quantitative analysis and characterization of…

图像与视频处理 · 电气工程与系统科学 2020-09-22 Jean Ollion , Charles Ollion

Cell sorting, the segregation of cells with different properties into distinct domains, is a key phenomenon in biological processes such as embryogenesis. We use a phase-field model of a confluent cell layer to study the role of activity in…

生物物理 · 物理学 2024-03-05 James N. Graham , Guanming Zhang , Julia M. Yeomans