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Numerous COVID-19 clinical decision support systems have been developed. However many of these systems do not have the merit for validity due to methodological shortcomings including algorithmic bias. Methods Logistic regression models were…

We present vivid, an R package for visualizing variable importance and variable interactions in machine learning models. The package provides a range of displays including heatmap and graph-based displays for viewing variable importance and…

统计计算 · 统计学 2024-10-15 Alan Inglis , Andrew Parnell , Catherine Hurley

The Coronavirus Disease 2019 (COVID-19) has a profound impact on global health and economy, making it crucial to build accurate and interpretable data-driven predictive models for COVID-19 cases to improve policy making. The extremely large…

机器学习 · 计算机科学 2023-05-02 Yangyi Zhang , Sui Tang , Guo Yu

The ongoing COVID-19 pandemic calls for a multi-faceted public health response comprising complementary interventions to control the spread of the disease while vaccines and therapies are developed. Many of these interventions need to be…

应用统计 · 统计学 2020-08-24 Andres Colubri , Kailash Yadav , Abhishek Jha , Pardis C. Sabeti

COVID-19 is an acute respiratory disease that has been classified as a pandemic by the World Health Organization. Characterization of this disease is still in its early stages. However, it is known to have high mortality rates, particularly…

A new method called the Survival Beran-based Neural Importance Model (SurvBeNIM) is proposed. It aims to explain predictions of machine learning survival models, which are in the form of survival or cumulative hazard functions. The main…

机器学习 · 计算机科学 2023-12-12 Lev V. Utkin , Danila Y. Eremenko , Andrei V. Konstantinov

In the era of "big data", it is becoming more of a challenge to not only build state-of-the-art predictive models, but also gain an understanding of what's really going on in the data. For example, it is often of interest to know which, if…

机器学习 · 统计学 2018-05-15 Brandon M. Greenwell , Bradley C. Boehmke , Andrew J. McCarthy

Traditionally, the identification of parameters in the formulation and solution of inverse problems considers that models, variables and mathematical parameters are free of uncertainties. This aspect simplifies the estimation process, but…

种群与进化 · 定量生物学 2020-06-02 Gustavo Barbosa Libotte , Fran Sérgio Lobato , Gustavo Mendes Platt

COVID-19 has been a public health emergency of international concern since early 2020. Reliable forecasting is critical to diminish the impact of this disease. To date, a large number of different forecasting models have been proposed,…

机器学习 · 计算机科学 2021-10-04 Yun Zhao , Yuqing Wang , Junfeng Liu , Haotian Xia , Zhenni Xu , Qinghang Hong , Zhiyang Zhou , Linda Petzold

The COVID-19 pandemic has profound global consequences on health, economic, social, political, and almost every major aspect of human life. Therefore, it is of great importance to model COVID-19 and other pandemics in terms of the broader…

机器学习 · 计算机科学 2020-10-09 Geoffrey C. Fox , Gregor von Laszewski , Fugang Wang , Saumyadipta Pyne

Variable importance measures (VIMs) aim to quantify the contribution of each input covariate to the predictability of a given output. With the growing interest in explainable AI, numerous VIMs have been proposed, many of which are heuristic…

统计方法学 · 统计学 2025-09-23 Angel Reyero-Lobo , Pierre Neuvial , Bertrand Thirion

Spatiotemporal modelling of infectious diseases such as COVID-19 involves using a variety of epidemiological metrics such as regional proportion of cases or regional positivity rates. Although observing their changes over time is critical…

The fast transmission rate of COVID-19 worldwide has made this virus the most important challenge of year 2020. Many mitigation policies have been imposed by the governments at different regional levels (country, state, county, and city) to…

应用统计 · 统计学 2022-05-04 Yue Bai , Abolfazl Safikhani , George Michailidis

Identifying key biomarkers for COVID-19 from high-dimensional multi-omics data is critical for advancing both diagnostic and pathogenesis research. In this study, we evaluated the applicability of the Quantum Support Vector Machine (QSVM)…

Recent advances in healthcare technologies have led to the availability of large amounts of biological samples across several techniques and applications. In particular, in the last few years, Raman spectroscopy analysis of biological…

定量方法 · 定量生物学 2025-06-24 Marco Piazza , Andrea Spinelli , Francesca Maggioni , Marzia Bedoni , Enza Messina

Severe infectious diseases such as the novel coronavirus (COVID-19) pose a huge threat to public health. Stringent control measures, such as school closures and stay-at-home orders, while having significant effects, also bring huge economic…

机器学习 · 计算机科学 2022-03-01 Runzhe Wan , Xinyu Zhang , Rui Song

We propose a novel approach that integrates machine learning into compartmental disease modeling to predict the progression of COVID-19. Our model is explainable by design as it explicitly shows how different compartments evolve and it uses…

Logistic Regression (LR) is a widely used statistical method in empirical binary classification studies. However, real-life scenarios oftentimes share complexities that prevent from the use of the as-is LR model, and instead highlight the…

SARS-CoV2, which causes coronavirus disease (COVID-19) is continuing to spread globally and has become a pandemic. People have lost their lives due to the virus and the lack of counter measures in place. Given the increasing caseload and…

Severe acute respiratory disease SARS-CoV-2 has had a found impact on public health systems and healthcare emergency response especially with respect to making decisions on the most effective measures to be taken at any given time. As…

机器学习 · 计算机科学 2023-09-19 Charithea Stylianides , Kleanthis Malialis , Panayiotis Kolios