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With the introduction of spectral-domain optical coherence tomography (SDOCT), much larger image datasets are routinely acquired compared to what was possible using the previous generation of time-domain OCT. Thus, there is a critical need…

Automatic blood vessel segmentation from retinal images plays an important role in the diagnosis of many systemic and eye diseases, including retinopathy of prematurity. Current state-of-the-art research in blood vessel segmentation from…

Early and accurate classification of retinal diseases is critical to counter vision loss and for guiding clinical management of retinal diseases. In this study, we proposed a deep learning method for retinal disease classification utilizing…

Purpose: To test the feasibility of using deep learning for optical coherence tomography angiography (OCTA) detection of diabetic retinopathy (DR). Methods: A deep learning convolutional neural network (CNN) architecture VGG16 was employed…

We develop a connection sensitive attention U-Net(CSAU) for accurate retinal vessel segmentation. This method improves the recent attention U-Net for semantic segmentation with four key improvements: (1) connection sensitive loss that…

Eye diseases are common in older Americans and can lead to decreased vision and blindness. Recent advancements in imaging technologies allow clinicians to capture high-quality images of the retinal blood vessels via Optical Coherence…

Accurate medical image segmentation is essential for diagnosis and treatment planning of diseases. Convolutional Neural Networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they are…

For accurate glaucoma diagnosis and monitoring, reliable retinal layer segmentation in OCT images is essential. However, existing 2D segmentation methods often suffer from slice-to-slice inconsistencies due to the lack of contextual…

Segmentation of retinal vessel images is critical to the diagnosis of retinopathy. Recently, convolutional neural networks have shown significant ability to extract the blood vessel structure. However, it remains challenging to refined…

An accurate and automated tissue segmentation algorithm for retinal optical coherence tomography (OCT) images is crucial for the diagnosis of glaucoma. However, due to the presence of the optic disc, the anatomical structure of the…

Optical coherence tomography angiography (OCTA) is an imaging technique that allows for non-invasive investigation of the microvasculature in the retina. OCTA uses laser light reflectance to measure moving blood cells. Hereby, it visualizes…

The automatic detection and localization of anatomical features in retinal imaging data are relevant for many aspects. In this work, we follow a data-centric approach to optimize classifier training for optic nerve head detection and…

In medical science, the use of computer science in disease detection and diagnosis is gaining popularity. Previously, the detection of disease used to take a significant amount of time and was less reliable. Machine learning (ML) techniques…

Purpose: This study explores the feasibility of using generative machine learning (ML) to translate Optical Coherence Tomography (OCT) images into Optical Coherence Tomography Angiography (OCTA) images, potentially bypassing the need for…

The lack of efficient segmentation methods and fully-labeled datasets limits the comprehensive assessment of optical coherence tomography angiography (OCTA) microstructures like retinal vessel network (RVN) and foveal avascular zone (FAZ),…

Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

Visible light optical coherence tomography (vis-OCT) is gaining traction for retinal imaging due to its high resolution and functional capabilities. However, the significant absorption of hemoglobin in the visible light range leads to…

Optical Coherence Tomography (OCT) is an imaging modality that has been widely adopted for visualizing corneal, retinal and limbal tissue structure with micron resolution. It can be used to diagnose pathological conditions of the eye, and…

Eye diseases have posed significant challenges for decades, but advancements in technology have opened new avenues for their detection and treatment. Machine learning and deep learning algorithms have become instrumental in this domain,…

Optical coherence tomography angiography (OCTA) is a non-invasive imaging modality that extends the functionality of OCT by extracting moving red blood cell signals from surrounding static biological tissues. OCTA has emerged as a valuable…