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Information molecules play a crucial role in molecular communication (MC), acting as carriers for information transfer. A common approach to get information molecules in MC involves harvesting them from the environment; however, the…

信息论 · 计算机科学 2025-08-08 Dongliang Jing , Linjuan Li , Zhen Cheng , Lin Lin , Andrew W. Eckford

A simple tight-coupling model of a molecular chemical engine is proposed. The efficiency of the chemical engine and its average velocity can be explicitly calculated. The diffusion constant is evaluated approximately using the fluctuation…

统计力学 · 物理学 2009-11-11 Hidetsugu Sakaguchi

Cellular cargo can be bound to cytoskeletal filaments by one or multiple active or passive molecular motors. Recent experiments have shown that the presence of auxiliary, nondriving motors, results in an enhanced processivity of the cargo,…

生物大分子 · 定量生物学 2019-03-27 Filippo Posta , Maria R. D'Orsogna , Tom Chou

Motivated by the benefits of multi-energy integration, this paper establishes a bi-level two-stage framework based on transactive control, in order to achieve optimal energy provision among interconnected multi-energy systems (MESs). At the…

最优化与控制 · 数学 2019-10-23 Yizhi Cheng , Peichao Zhang , Xuezhi Liu

Many biological functions are executed by molecular machines, which consume energy and convert it into mechanical work. Biological machines have evolved to transport cargo, facilitate folding of proteins and RNA, remodel chromatin and…

生物物理 · 物理学 2020-04-15 Mauro L. Mugnai , Changbong Hyeon , Michael Hinczewski , D. Thirumalai

Inside cells, various cargos are transported by teams of molecular motors. Intriguingly, the motors involved generally have opposite pulling directions, and the resulting cargo dynamics is a biased stochastic motion. It is an open question…

生物物理 · 物理学 2017-09-20 Sarah Klein , Cécile Appert-Rolland , Ludger Santen

We consider the thermodynamics of chemical coupling from the viewpoint of free energy transduction efficiency. In contrast to an external parameter-driven stochastic energetics setup, the dynamic change of the equilibrium distribution…

统计力学 · 物理学 2022-06-28 Kyogo Kawaguchi , Masaki Sano

In this paper, a diffusion-based molecular communication channel between two nano-machines is considered. The effect of the amount of memory on performance is characterized, and a simple memory-limited decoder is proposed and its…

We consider nano-sized artificial or biological machines working in steady state enforced by imposing non-equilibrium concentrations of solutes or by applying external forces, torques or electric fields. For unicyclic and strongly coupled…

统计力学 · 物理学 2015-05-20 Udo Seifert

The dynamics of motor protein molecules that have two subunits is investigated using simple discrete stochastic models. Exact steady-state analytical expressions are obtained for velocities and dispersions for any number of intermediate…

软凝聚态物质 · 物理学 2015-06-25 Anatoly B. Kolomeisky , Hubert Phillips

Molecular motor proteins serve as an essential component of intracellular transport by generating forces to haul cargoes along cytoskeletal filaments. Two species of motors that are directed oppositely (e.g. kinesin, dynein) can be attached…

亚细胞过程 · 定量生物学 2017-05-10 Christopher E. Miles , James P. Keener

Machines enabled the Industrial Revolution and are central to modern technological progress: A machine's parts transmit forces, motion, and energy to one another in a predetermined manner. Today's engineering frontier, building artificial…

软凝聚态物质 · 物理学 2021-11-18 A. Aubret , Q. Martinet , J. Palacci

In living cells, molecular motors convert chemical energy into mechanical work. Its thermodynamic energy efficiency, i.e. the ratio of output mechanical work to input chemical energy, is usually high. However, using two-state models, we…

生物物理 · 物理学 2015-03-06 Yunxin Zhang

We show that finite-size, disordered molecular networks can mediate highly efficient, coherent excitation transfer which is robust against ambient dephasing and associated with strong multi-site entanglement. Such optimal, random molecular…

The efficiency at maximum power (EMP) for tight-coupling molecular motors is investigated within the framework of irreversible thermodynamics. It is found that the EMP depends merely on the constitutive relation between the thermodynamic…

统计力学 · 物理学 2013-12-13 Z. C. Tu

Here we generalize our previous model of molecular motors trafficking subdiffusing cargos in viscoelastic cytosol by (i) including mechanochemical coupling between cyclic conformational fluctuations of the motor protein driven by the…

生物物理 · 物理学 2015-05-01 Igor Goychuk

Technical systems have evolved over time into large and complex Interwoven Systems consisting of several to a huge number of (possibly heterogeneous) subsystems that have interdependencies. The resultant mutual influences among subsystems…

多智能体系统 · 计算机科学 2018-07-24 Neeraj Mumbuveetil Sasankan

The diffusion of a molecular motor in the presence of a constant external force is considered on the basis of a simple theoretical model. The motor is represented by a Brownian particle moving in a series of parabolic potentials placed…

统计力学 · 物理学 2016-06-01 Ryota Shinagawa , Kazuo Sasaki

Understanding how the effectiveness of natural photosynthetic energy harvesting systems arises from the interplay between quantum coherence and environmental noise represents a significant challenge for quantum theory. Recently it has begun…

生物物理 · 物理学 2015-06-16 E. K. Irish , R. Gómez-Bombarelli , B. W. Lovett

The cost of information processing in physical systems calls for a trade-off between performance and energetic expenditure. Here we formulate and study a computation-dissipation bottleneck in mesoscopic systems used as input-output devices.…

统计力学 · 物理学 2023-07-06 Alessandro Ingrosso , Emanuele Panizon