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Deep learning (DL) models have shown significant potential in Alzheimer's Disease (AD) classification. However, understanding and interpreting these models remains challenging, which hinders the adoption of these models in clinical…

计算机视觉与模式识别 · 计算机科学 2024-09-10 Thomas Yu Chow Tam , Litian Liang , Ke Chen , Haohan Wang , Wei Wu

Alzheimer's Disease (AD) detection employs machine learning classification models to distinguish between individuals with AD and those without. Different from conventional classification tasks, we identify within-class variation as a…

音频与语音处理 · 电气工程与系统科学 2025-09-29 Jiawen Kang , Dongrui Han , Lingwei Meng , Jingyan Zhou , Jinchao Li , Xixin Wu , Helen Meng

An interpretable machine learning (ML) framework is introduced to enhance the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) by ensuring robustness of the ML models' interpretations. The dataset used comprises…

Autism, also known as Autism Spectrum Disorder (or ASD), is a neurological disorder. Its main symptoms include difficulty in (verbal and/or non-verbal) communication, and rigid/repetitive behavior. These symptoms are often indistinguishable…

计算机视觉与模式识别 · 计算机科学 2023-07-18 Asha Rani , Pankaj Yadav , Yashaswi Verma

Ensemble learning use multiple algorithms to obtain better predictive performance than any single one of its constituent algorithms could. With growing popularity of deep learning, researchers have started to ensemble them for various…

机器学习 · 计算机科学 2019-05-31 Ning An , Huitong Ding , Jiaoyun Yang , Rhoda Au , Ting Fang Alvin Ang

Existing screening tools for early detection of autism are expensive, cumbersome, time-intensive, and sometimes fall short in predictive value. In this work, we apply Machine Learning (ML) to gold standard clinical data obtained across…

计算机与社会 · 计算机科学 2017-03-20 Halim Abbas , Ford Garberson , Eric Glover , Dennis P Wall

Early and accurate detection of Alzheimer's disease (AD) remains a major challenge in medical diagnosis due to its subtle onset and progressive nature. This research introduces an explainable ensemble learning Framework designed to classify…

机器学习 · 计算机科学 2026-03-06 Nishan Mitra

Dementia, a debilitating neurological condition affecting millions worldwide, presents significant diagnostic challenges. In this work, we introduce DEFORMISE, a novel DEep learning Framework for dementia diagnOsis of eldeRly patients using…

图像与视频处理 · 电气工程与系统科学 2025-11-21 Nikolaos Ntampakis , Konstantinos Diamantaras , Ioanna Chouvarda , Vasileios Argyriou , Panagiotis Sarigianndis

Although deep learning models for abnormality classification can perform well in screening mammography, the demographic, imaging, and clinical characteristics associated with increased risk of model failure remain unclear. This…

Alzheimer's disease (AD) is one of the most common public health issues the world is facing today. This disease has a high prevalence primarily in the elderly accompanying memory loss and cognitive decline. AD detection is a challenging…

图像与视频处理 · 电气工程与系统科学 2022-04-04 Zahraa Sh. Aaraji , Hawraa H. Abbas

In this work, we introduce a technique of deriving symmetric connectivity matrices from regional histograms of grey-matter volume estimated from T1-weighted MRIs. We then validated the technique by inputting the connectivity matrices into a…

定量方法 · 定量生物学 2020-05-28 Matthew Leming , Simon Baron-Cohen , John Suckling

Alzheimer's Disease (AD) is the most common neurodegenerative disorder with one of the most complex pathogeneses, making effective and clinically actionable decision support difficult. The objective of this study was to develop a novel…

机器学习 · 计算机科学 2022-09-27 Michal Golovanevsky , Carsten Eickhoff , Ritambhara Singh

The subject of "fairness" in artificial intelligence (AI) refers to assessing AI algorithms for potential bias based on demographic characteristics such as race and gender, and the development of algorithms to address this bias. Most…

计算机视觉与模式识别 · 计算机科学 2021-07-02 Esther Puyol-Anton , Bram Ruijsink , Stefan K. Piechnik , Stefan Neubauer , Steffen E. Petersen , Reza Razavi , Andrew P. King

Resting-state functional MRI (rs-fMRI) is a rich imaging modality that captures spontaneous brain activity patterns, revealing clues about the connectomic organization of the human brain. While many rs-fMRI studies have focused on static…

机器学习 · 计算机科学 2019-08-20 Meenakshi Khosla , Keith Jamison , Amy Kuceyeski , Mert R. Sabuncu

Current models on Explainable Artificial Intelligence (XAI) have shown an evident and quantified lack of reliability for measuring feature-relevance when statistically entangled features are proposed for training deep classifiers. There has…

信号处理 · 电气工程与系统科学 2023-02-27 Juan Manuel Mayor-Torres , Sara Medina-DeVilliers , Tessa Clarkson , Matthew D. Lerner , Giuseppe Riccardi

Collecting and accessing a large amount of medical data is very time-consuming and laborious, not only because it is difficult to find specific patients but also because it is required to resolve the confidentiality of a patient's medical…

声音 · 计算机科学 2021-03-04 Junghyun Koo , Jie Hwan Lee , Jaewoo Pyo , Yujin Jo , Kyogu Lee

Autism spectrum disorders (ASDs) are developmental conditions characterized by restricted interests and difficulties in communication. The complexity of ASD has resulted in a deficiency of objective diagnostic biomarkers. Deep learning…

图像与视频处理 · 电气工程与系统科学 2025-03-28 Xinyuan Zheng , Orren Ravid , Robert A. J. Barry , Yoojean Kim , Qian Wang , Young-geun Kim , Xi Zhu , Xiaofu He

Attention Deficit Hyperactivity Disorder (ADHD) and Autism Spectrum Disorder (ASD) are neurodevelopmental conditions which impact on a significant number of children and adults. Currently, the diagnosis of such disorders is done by experts…

计算机视觉与模式识别 · 计算机科学 2016-12-08 Shashank Jaiswal , Michel Valstar , Alinda Gillott , David Daley

Autism spectrum disorder(ASD) is a lifelong neurodevelopmental condition that affects social communication and behavior. Investigating functional magnetic resonance imaging (fMRI)-based brain functional connectome can aid in the…

神经元与认知 · 定量生物学 2023-07-21 Anushree Bannadabhavi , Soojin Lee , Wenlong Deng , Xiaoxiao Li

This study is based on the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset and aims to explore early detection and disease progression in Alzheimer's disease (AD). We employ innovative data preprocessing strategies, including the…

机器学习 · 计算机科学 2024-02-14 Mingyang Li , Hongyu Liu , Yixuan Li , Zejun Wang , Yuan Yuan , Honglin Dai