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Multimodal MRI offers complementary multi-scale information to characterize the brain structure. However, it remains challenging to effectively integrate multimodal MRI while achieving neuroscience interpretability. Here we propose to use…

神经元与认知 · 定量生物学 2025-12-15 Chengzhi Xia , Jianwei Chen , Yixuan Jiang , Qi Yan , Chao Li

Differential Dynamic Microscopy (DDM) analyzes traditional real-space microscope images to extract information on sample dynamics in a way akin to light scattering, by decomposing each image in a sequence into Fourier modes, and evaluating…

软凝聚态物质 · 物理学 2017-11-10 Fabio Giavazzi , Paolo Edera , Peter J. Lu , Roberto Cerbino

The accuracy of deformable image registration (DIR) has a significant dosimetric impact in radiation treatment planning. We evaluated accuracy of various DIR algorithms using variations of the deformation point and volume. The reference…

This work proposes NePhi, a generalizable neural deformation model which results in approximately diffeomorphic transformations. In contrast to the predominant voxel-based transformation fields used in learning-based registration…

计算机视觉与模式识别 · 计算机科学 2024-09-30 Lin Tian , Hastings Greer , Raúl San José Estépar , Roni Sengupta , Marc Niethammer

We introduce the Push-Forward Signed Distance Morphometric (PF-SDM) for shape quantification in biomedical imaging. The PF-SDM compactly encodes geometric and topological properties of closed shapes, including their skeleton and symmetries.…

计算机视觉与模式识别 · 计算机科学 2025-10-31 Roua Rouatbi , Juan-Esteban Suarez Cardona , Alba Villaronga-Luque , Jesse V. Veenvliet , Ivo F. Sbalzarini

Understanding how networks of neurons process information is one of the key challenges in modern neuroscience. A necessary step to achieve this goal is to be able to observe the dynamics of large populations of neurons over a large area of…

图像与视频处理 · 电气工程与系统科学 2022-03-09 Pingfan Song , Herman Verinaz Jadan , Carmel L. Howe , Amanda J. Foust , Pier Luigi Dragotti

This paper introduces the Neural Differential Manifold (NDM), a novel neural network architecture that explicitly incorporates geometric structure into its fundamental design. Departing from conventional Euclidean parameter spaces, the NDM…

机器学习 · 计算机科学 2025-10-30 Di Zhang

Brain mapping research in most neuroanatomical laboratories relies on conventional processing techniques, which often introduce histological artifacts such as tissue tears and tissue loss. In this paper we present techniques and algorithms…

图形学 · 计算机科学 2017-12-29 Nitin Agarwal , Xiangmin Xu , Gopi Meenakshisundaram

Spatially aligning medical images from different modalities remains a challenging task, especially for intraoperative applications that require fast and robust algorithms. We propose a weakly-supervised, label-driven formulation for…

计算机视觉与模式识别 · 计算机科学 2018-06-05 Yipeng Hu , Marc Modat , Eli Gibson , Nooshin Ghavami , Ester Bonmati , Caroline M. Moore , Mark Emberton , J. Alison Noble , Dean C. Barratt , Tom Vercauteren

Partial shapes correspondences is a problem that often occurs in computer vision (occlusion, evolution in time...). In medical imaging, data may come from different modalities and be acquired under different conditions which leads to…

图像与视频处理 · 电气工程与系统科学 2022-04-13 Pierre-Louis Antonsanti , Thomas Benseghir , Vincent Jugnon , Mario Ghosn , Perrine Chassat , Irène Kaltenmark , Joan Glaunès

Brain-to-image decoding has been recently propelled by the progress in generative AI models and the availability of large ultra-high field functional Magnetic Resonance Imaging (fMRI). However, current approaches depend on complicated…

计算机视觉与模式识别 · 计算机科学 2025-05-21 Marlène Careil , Yohann Benchetrit , Jean-Rémi King

Understanding and predicting the progression of neurodegenerative diseases remains a major challenge in medical AI, with significant implications for early diagnosis, disease monitoring, and treatment planning. However, most available…

计算机视觉与模式识别 · 计算机科学 2026-04-27 Nivetha Jayakumar , Swakshar Deb , Bahram Jafrasteh , Qingyu Zhao , Miaomiao Zhang

Deep learning has proven to successfully learn variations in tissue and cell morphology. Training of such models typically relies on expensive manual annotations. Here we conjecture that spatially resolved gene expression, e.i., the…

定量方法 · 定量生物学 2023-12-11 Axel Andersson , Gabriele Partel , Leslie Solorzano , Carolina Wählby

Recent advances in imaging and high-performance computing have made it possible to image the entire human brain at the cellular level. This is the basis to study the multi-scale architecture of the brain regarding its subdivision into brain…

图像与视频处理 · 电气工程与系统科学 2023-11-29 Jan-Oliver Kropp , Christian Schiffer , Katrin Amunts , Timo Dickscheid

We propose a novel machine learning strategy for studying neuroanatomical shape variation. Our model works with volumetric binary segmentation images, and requires no pre-processing such as the extraction of surface points or a mesh. The…

计算机视觉与模式识别 · 计算机科学 2024-10-30 Evan M. Yu , Mert R. Sabuncu

In cognitive science and AI, a longstanding question is whether machines learn representations that align with those of the human mind. While current models show promise, it remains an open question whether this alignment is superficial or…

神经元与认知 · 定量生物学 2025-10-27 Craig Sanders , Billy Dickson , Sahaj Singh Maini , Robert Nosofsky , Zoran Tiganj

The segmentation of substantial brain lesions is a significant and challenging task in the field of medical image segmentation. Substantial brain lesions in brain imaging exhibit high heterogeneity, with indistinct boundaries between lesion…

计算机视觉与模式识别 · 计算机科学 2025-08-07 Hongming Wang , Yifeng Wu , Huimin Huang , Hongtao Wu , Jia-Xuan Jiang , Xiaodong Zhang , Hao Zheng , Xian Wu , Yefeng Zheng , Jinping Xu , Jing Cheng

We present a novel algorithm named 3DPIFCM, for automatic segmentation of noisy MRI Brain images. The algorithm is an extension of a well-known IFCM (Improved Fuzzy C-Means) algorithm. It performs fuzzy segmentation and introduces a fitness…

计算机视觉与模式识别 · 计算机科学 2020-02-12 Arie Agranonik , Maya Herman , Mark Last

Statistical shape modeling is an essential tool for the quantitative analysis of anatomical populations. Point distribution models (PDMs) represent the anatomical surface via a dense set of correspondences, an intuitive and easy-to-use…

图像与视频处理 · 电气工程与系统科学 2022-01-11 Wenzheng Tao , Riddhish Bhalodia , Shireen Elhabian

This article introduces a full mathematical and numerical framework for treating functional shapes (or fshapes) following the landmarks of shape spaces and shape analysis. Functional shapes can be described as signal functions supported on…

计算几何 · 计算机科学 2014-04-25 Benjamin Charlier , Nicolas Charon , Alain Trouvé