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Accurate assessment of Parkinsonian tremor is vital for monitoring disease progression and evaluating treatment efficacy. We introduce a pixel-based deep learning model designed to analyse postural tremor in Parkinson's disease (PD) from…

计算机视觉与模式识别 · 计算机科学 2024-09-04 Felipe Duque-Quiceno , Grzegorz Sarapata , Yuriy Dushin , Miles Allen , Jonathan O'Keeffe

Parkinson's disease (PD) is a neurodegenerative disease affecting about 1% of people over the age of 60, causing motor impairments that impede hand coordination activities such as writing and drawing. Many approaches have tried to support…

计算机视觉与模式识别 · 计算机科学 2025-12-30 Mhd Adnan Albani , Riad Sonbol

Parkinson's disease (PD) is a non-curable disease that commonly found among elders that greatly reduce their quality of life. PD primarily affects the gait pattern and slowly changes the walking gait from the normality to disability. The…

机器学习 · 计算机科学 2021-02-02 Musthaq Ahamed , P. D. S. H. Gunawardane , Nimali T. Medagedara

Accurately quantifying motor characteristics in Parkinson disease (PD) is crucial for monitoring disease progression and optimizing treatment strategies. The finger-tapping test is a standard motor assessment. Clinicians visually evaluate a…

计算机视觉与模式识别 · 计算机科学 2025-11-14 Tahereh Zarrat Ehsan , Michael Tangermann , Yağmur Güçlütürk , Bastiaan R. Bloem , Luc J. W. Evers

Understanding how treatment effects vary on individual characteristics is critical in the contexts of personalized medicine, personalized advertising and policy design. When the characteristics are of practical interest are only a subset of…

统计方法学 · 统计学 2023-05-03 Peng Wu , ShaSha Han , Xingwei Tong , Runze Li

The stage and severity of Parkinson's disease (PD) is an important factor to consider for taking effective therapeutic decisions. Although the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) provides an…

应用统计 · 统计学 2018-05-30 R. Prashanth , Sumantra Dutta Roy

This paper presents a method for building patient-based networks that we call Precision disease networks, and its uses for predicting medical outcomes. Our methodology consists of building networks, one for each patient or case, that…

定量方法 · 定量生物学 2019-11-01 J. Cabrera , D. Amaratunga , W. Kostis , J Kostis

Speech-based algorithms have gained interest for the management of behavioral health conditions such as depression. We explore a speech-based transfer learning approach that uses a lightweight encoder and that transfers only the encoder…

音频与语音处理 · 电气工程与系统科学 2024-12-30 Amir Harati , Elizabeth Shriberg , Tomasz Rutowski , Piotr Chlebek , Yang Lu , Ricardo Oliveira

Parkinson's disease (PD) poses challenges in diagnosis and monitoring due to its progressive nature and complex symptoms. This study introduces a novel approach utilizing surface electromyography (sEMG) to objectively assess PD severity,…

Negative transfer in training of acoustic models for automatic speech recognition has been reported in several contexts such as domain change or speaker characteristics. This paper proposes a novel technique to overcome negative transfer by…

机器学习 · 计算机科学 2015-09-18 Mortaza Doulaty , Oscar Saz , Thomas Hain

Severity assessment of Parkinson's disease (PD) using wearable sensors offers an effective, objective basis for clinical management. However, general-purpose time series models often lack pathological specificity in feature extraction,…

机器学习 · 计算机科学 2025-10-14 Weiming Zhao , Xulong Wang , Jun Qi , Yun Yang , Po Yang

Parkinson's disease (PD) is a slowly progressive debilitating neurodegenerative disease which is prominently characterised by motor symptoms. Indoor localisation, including number and speed of room to room transitions, provides a proxy…

机器学习 · 计算机科学 2022-05-13 Ferdian Jovan , Ryan McConville , Catherine Morgan , Emma Tonkin , Alan Whone , Ian Craddock

In observational studies, the recorded treatment assignment is not purely random, but it is influenced by external factors such as patient characteristics, reimbursement policies, and existing guidelines. Therefore, the treatment effect can…

统计方法学 · 统计学 2024-09-02 Sara Poletto , Enrico Longato , Erica Tavazzi , Martina Vettoretti

Parkinson's disease (PD) is a common neurodegenerative disease with a high degree of heterogeneity in its clinical features, rate of progression, and change of variables over time. In this work, we present a novel data-driven, network-based…

应用统计 · 统计学 2020-07-01 Sanjukta Krishnagopal , Rainer Von Coelln , Lisa M. Shulman , Michelle Girvan

The speech of people with Parkinson's Disease (PD) has been shown to hold important clues about the presence and progression of the disease. We investigate the factors based on which humans experts make judgments of the presence of disease…

Up to 90% of patients with Parkinson's disease (PD) suffer from hypokinetic dysathria (HD) which is also manifested in the field of phonation. Clinical signs of HD like monoloudness, monopitch or hoarse voice are usually quantified by…

Parkinson's disease (PD) is commonly characterized by several motor symptoms, such as bradykinesia, akinesia, rigidity, and tremor. The analysis of patients' fine motor control, particularly handwriting, is a powerful tool to support PD…

计算机视觉与模式识别 · 计算机科学 2021-01-26 Moises Diaz , Momina Moetesum , Imran Siddiqi , Gennaro Vessio

Early and accurate detection of Parkinson's disease (PD) remains a critical challenge in medical diagnostics due to the subtlety of early-stage symptoms and the complex, non-linear relationships inherent in biomedical data. Traditional…

机器学习 · 计算机科学 2026-02-10 Olamide Samuel Oseni , Ibraheem Omotolani Obanla , Toheeb Aduramomi Jimoh

Parkinson's disease (PD) is a progressive neurological disorder that impacts the quality of life significantly, making in-home monitoring of motor symptoms such as Freezing of Gait (FoG) critical. However, existing symptom monitoring…

机器学习 · 计算机科学 2026-04-16 Shovito Barua Soumma , Daniel Peterson , Shyamal Mehta , Hassan Ghasemzadeh

Parkinson's disease is a neurodegenerative disease that can affect a person's movement, speech, dexterity, and cognition. Clinicians primarily diagnose Parkinson's disease by performing a clinical assessment of symptoms. However,…

神经元与认知 · 定量生物学 2018-11-16 Patrick Schwab , Walter Karlen