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Cardiac digital twins (CDTs) of human cardiac electrophysiology (EP) are digital replicas of patient hearts that match like-for-like clinical observations. The electrocardiogram (ECG), as the most prevalent non-invasive observation of…

医学物理 · 物理学 2024-07-26 Elena Zappon , Matthias A. F. Gsell , Karli Gillette , Gernot Plank

The variability in ECG readings influenced by individual patient characteristics has posed a considerable challenge to adopting automated ECG analysis in clinical settings. A novel feature fusion technique termed SACC (Self Attentive…

信号处理 · 电气工程与系统科学 2025-02-25 Shreya Srivastava , Durgesh Kumar , Ram Jiwari , Sandeep Seth , Deepak Sharma

Accurate localization of myocardial infarction is essential for risk stratification. While LGE-MRI remains the gold standard, it is resource-intensive. Integrating cine MRI with ECG enables a more detailed representation of infarct…

计算机视觉与模式识别 · 计算机科学 2026-05-22 Mengxiao Wang , Yilin Lyu , Julia Camps , Ching Hui Sia , Mark Yan-Yee Chan , Yanrui Jin , Shuzhi Sam Ge , Chengliang Liu , Lei Li

A digital health twin can be defined as a virtual model of a physical person, in this specific case, a patient. This virtual model is constituted by multidimensional data that can host from clinical, molecular and therapeutic parameters to…

计算机与社会 · 计算机科学 2022-12-02 Manuel Cossio

A patient's digital twin is a computational model that describes the evolution of their health over time. Digital twins have the potential to revolutionize medicine by enabling individual-level computer simulations of human health, which…

Mathematical models of cardiac electrical activity are one of the most important tools for elucidating information about the heart diagnostic. Even though it is one of the major problems in biomedical research, an efficient mathematical…

Deep learning applied to electrocardiogram (ECG) data can be used to achieve personal authentication in biometric security applications, but it has not been widely used to diagnose cardiovascular disorders. We developed a deep learning…

机器学习 · 计算机科学 2020-12-02 Song-Kyoo Kim , Chan Yeob Yeun , Paul D. Yoo , Nai-Wei Lo , Ernesto Damiani

The heart's contraction is caused by electrical excitation which propagates through the heart muscle. It was recently shown that the electrical excitation can be computed from the contractile motion of a simulated piece of heart muscle…

医学物理 · 物理学 2023-05-16 Jan Lebert , Daniel Deng , Lei Fan , Lik Chuan Lee , Jan Christoph

One of the challenges in the development of patient-specific models of cardiac arrhythmias for clinical applications has been accounting for myocardial fiber organization. The fiber varies significantly from heart to heart, but cannot be…

医学物理 · 物理学 2023-07-22 Jiyue He , Arkady Pertsov , John Bullinga , Rahul Mangharam

Virtual heart models have been proposed to enhance the safety of implantable cardiac devices through closed loop validation. To communicate with a virtual heart, devices have been driven by cardiac signals at specific sites. As a result,…

系统与控制 · 计算机科学 2017-03-06 Weiwei Ai , Nitish Patel , Partha Roop , Avinash Malik , Nathan Allen , Mark L. Trew

The inverse mechano-electrical problem in cardiac electrophysiology is the attempt to reconstruct electrical excitation or action potential wave patterns from the heart's mechanical deformation that occurs in response to electrical…

图像与视频处理 · 电气工程与系统科学 2021-11-10 Jan Christoph , Jan Lebert

In primary diagnosis and analysis of heart defects, an ECG signal plays a significant role. This paper presents a model for the prediction of ventricular tachycardia arrhythmia using noise filtering, a unique set of ECG features, and a…

信号处理 · 电气工程与系统科学 2021-12-28 Pampa Howladar , Manodipan Sahoo

Electrocardiogram (ECG)-based models have achieved strong performance in diagnostic tasks, yet they remain limited in modeling how cardiac dynamics evolve under external interventions. In particular, existing approaches focus primarily on…

人工智能 · 计算机科学 2026-05-19 Zhikang Chen , Yue Wang , Sen Cui , Yu Zhang , Changshui Zhang , Tianling Ren , Tingting Zhu

Objective: To determine if a realistic, but computationally efficient model of the electrocardiogram can be used to pre-train a deep neural network (DNN) with a wide range of morphologies and abnormalities specific to a given condition -…

机器学习 · 计算机科学 2022-01-03 Ismail Sadiq , Erick A. Perez-Alday , Amit J. Shah , Ali Bahrami Rad , Reza Sameni , Gari D. Clifford

Computer-based simulations of non-invasive cardiac electrical outputs, such as electrocardiograms and body surface potential maps, usually entail severe computational costs due to the need of capturing fine-scale processes and to the…

数值分析 · 数学 2023-08-09 Elena Zappon , Andrea Manzoni , Alfio Quarteroni

In this paper, we present a novel Image Fusion Model (IFM) for ECG heart-beat classification to overcome the weaknesses of existing machine learning techniques that rely either on manual feature extraction or direct utilization of 1D raw…

信号处理 · 电气工程与系统科学 2021-05-31 Zeeshan Ahmad , Anika Tabassum , Naimul Khan , Ling Guan

The rapid advancements in Artificial Intelligence, specifically Machine Learning (ML) and Deep Learning (DL), have opened new prospects in medical sciences for improved diagnosis, prognosis, and treatment of severe health conditions. This…

机器学习 · 计算机科学 2024-12-11 Atit Pokharel , Shashank Dahal , Pratik Sapkota , Bhupendra Bimal Chhetri

Cardiovascular hemodynamic fields provide valuable medical decision markers for coronary artery disease. Computational fluid dynamics (CFD) is the gold standard for accurate, non-invasive evaluation of these quantities in silico. In this…

Interest in the application of engineering methods to problems in congenital heart disease has gained increased popularity over the past decade. The use of computational simulation to examine common clinical problems including single…

医学物理 · 物理学 2011-01-20 Irene Vignon Clementel , Alison L. Marsden , Jeffrey A. Feinstein

The use of mechanistic models in clinical studies is limited by the lack of multi-modal patients data representing different anatomical and physiological processes. For example, neuroimaging datasets do not provide a sufficient…

机器学习 · 计算机科学 2025-09-18 Jaume Banus , Maxime Sermesant , Oscar Camara , Marco Lorenzi