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This paper introduces the novel concept of few-shot weakly supervised learning for pathology Whole Slide Image (WSI) classification, denoted as FSWC. A solution is proposed based on prompt learning and the utilization of a large language…

计算机视觉与模式识别 · 计算机科学 2024-01-30 Linhao Qu , Xiaoyuan Luo , Kexue Fu , Manning Wang , Zhijian Song

Malignant lymphoma subtype classification directly impacts treatment strategies and patient outcomes, necessitating classification models that achieve both high accuracy and sufficient explainability. This study proposes a novel explainable…

计算机视觉与模式识别 · 计算机科学 2025-03-04 Daiki Nishiyama , Hiroaki Miyoshi , Noriaki Hashimoto , Koichi Ohshima , Hidekata Hontani , Ichiro Takeuchi , Jun Sakuma

The effective management of brain tumors relies on precise typing, subtyping, and grading. This study advances patient care with findings from rigorous multiple instance learning experimentations across various feature extractors and…

计算机视觉与模式识别 · 计算机科学 2024-03-11 Ekansh Chauhan , Amit Sharma , Megha S Uppin , C. V. Jawahar , P. K. Vinod

Whole Slide Imaging (WSI) has become a gold standard in cancer diagnosis, inspecting multi-scale information from cellular to tissue levels. Processing an entire WSI directly is infeasible due to GPU memory constraints; thus, Multiple…

图像与视频处理 · 电气工程与系统科学 2026-05-08 Tianyi Zhang , Sicheng Chen , Borui Kang , Dankai Liao , Qiaochu Xue , Bochong Zhang , Fei Xia , Zeyu Liu , Yueming Jin

Whole slide images (WSI) provide valuable phenotypic information for histological assessment and malignancy grading of tumors. The WSI-based grading promises to provide rapid diagnostic support and facilitate digital health. Currently, the…

图像与视频处理 · 电气工程与系统科学 2022-10-05 Lipei Zhang , Yiran Wei , Ying Fu , Stephen Price , Carola-Bibiane Schönlieb , Chao Li

When supervising an object detector with weakly labeled data, most existing approaches are prone to trapping in the discriminative object parts, e.g., finding the face of a cat instead of the full body, due to lacking the supervision on the…

计算机视觉与模式识别 · 计算机科学 2017-11-28 Siyang Li , Xiangxin Zhu , Qin Huang , Hao Xu , C. -C. Jay Kuo

Deep-learning models based on whole-slide digital pathology images (WSIs) become increasingly popular for predicting molecular biomarkers. Instance-based models has been the mainstream strategy for predicting genetic alterations using WSIs…

定量方法 · 定量生物学 2022-06-02 Bangwei Guo , Xingyu Li , Miaomiao Yang , Hong Zhang , Xu Steven Xu

\textit{Multiple Instance Learning} (MIL) is concerned with learning from bags of instances, where only bag labels are given and instance labels are unknown. Existent approaches in this field were mainly designed for the bag-level label…

机器学习 · 计算机科学 2019-05-30 Minlong Peng , Qi Zhang

Whole-slide images (WSIs) are critical for cancer diagnosis due to their ultra-high resolution and rich semantic content. However, their massive size and the limited availability of fine-grained annotations pose substantial challenges for…

计算机视觉与模式识别 · 计算机科学 2025-06-30 Daoxi Cao , Hangbei Cheng , Yijin Li , Ruolin Zhou , Xuehan Zhang , Xinyi Li , Binwei Li , Xuancheng Gu , Jianan Zhang , Xueyu Liu , Yongfei Wu

Whole slide image (WSI) classification is a critical task in computational pathology. However, the gigapixel-size of such images remains a major challenge for the current state of deep-learning. Current methods rely on multiple-instance…

计算机视觉与模式识别 · 计算机科学 2023-10-04 Etienne Pochet , Rami Maroun , Roger Trullo

In computational pathology, multiple instance learning (MIL) is widely used to circumvent the computational impasse in giga-pixel whole slide image (WSI) analysis. It usually consists of two stages: patch-level feature extraction and…

图像与视频处理 · 电气工程与系统科学 2023-09-21 Beidi Zhao , Wenlong Deng , Zi Han , Li , Chen Zhou , Zuhua Gao , Gang Wang , Xiaoxiao Li

This paper attacks an emerging challenge of multi-modal retinal disease recognition. Given a multi-modal case consisting of a color fundus photo (CFP) and an array of OCT B-scan images acquired during an eye examination, we aim to build a…

计算机视觉与模式识别 · 计算机科学 2021-09-28 Xirong Li , Yang Zhou , Jie Wang , Hailan Lin , Jianchun Zhao , Dayong Ding , Weihong Yu , Youxin Chen

Contrastive Language Image Pre-training (CLIP) has recently demonstrated success across various tasks due to superior feature representation empowered by image-text contrastive learning. However, the instance discrimination method used by…

计算机视觉与模式识别 · 计算机科学 2024-11-07 Xiang An , Kaicheng Yang , Xiangzi Dai , Ziyong Feng , Jiankang Deng

We introduce ReaMIL (Reasoning- and Evidence-Aware MIL), a multiple instance learning approach for whole-slide histopathology that adds a light selection head to a strong MIL backbone. The head produces soft per-tile gates and is trained…

计算机视觉与模式识别 · 计算机科学 2026-04-08 Hyun Do Jung , Jungwon Choi , Hwiyoung Kim

Whole slide image (WSI) classification is a crucial problem for cancer diagnostics in clinics and hospitals. A WSI, acquired at gigapixel size, is commonly tiled into patches and processed by multiple-instance learning (MIL) models.…

计算机视觉与模式识别 · 计算机科学 2024-10-10 Doanh C. Bui , Jin Tae Kwak

We describe a novel weakly supervised deep learning framework that combines both the discriminative and generative models to learn meaningful representation in the multiple instance learning (MIL) setting. MIL is a weakly supervised…

机器学习 · 计算机科学 2018-07-09 Shabnam Ghaffarzadegan

Whole slide image (WSI) classification requires repetitive zoom-in and out for pathologists, as only small portions of the slide may be relevant to detecting cancer. Due to the lack of patch-level labels, multiple instance learning (MIL) is…

计算机视觉与模式识别 · 计算机科学 2023-11-30 Seongho Keum , Sanghyun Kim , Soojeong Lee , Juho Lee

Pathology computing has dramatically improved pathologists' workflow and diagnostic decision-making processes. Although computer-aided diagnostic systems have shown considerable value in whole slide image (WSI) analysis, the problem of…

计算机视觉与模式识别 · 计算机科学 2024-11-19 Yonghuang Wu , Xuan Xie , Xinyuan Niu , Chengqian Zhao , Jinhua Yu

Though multiple instance learning (MIL) has been a foundational strategy in computational pathology for processing whole slide images (WSIs), current approaches are designed for traditional hematoxylin and eosin (H&E) slides rather than…

图像与视频处理 · 电气工程与系统科学 2024-11-15 Marc Harary , Eliezer M. Van Allen , William Lotter

Weakly supervised object detection (WSOD) is a challenging task when provided with image category supervision but required to simultaneously learn object locations and object detectors. Many WSOD approaches adopt multiple instance learning…

计算机视觉与模式识别 · 计算机科学 2019-04-12 Fang Wan , Chang Liu , Wei Ke , Xiangyang Ji , Jianbin Jiao , Qixiang Ye
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