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Benefiting from the powerful expressive capability of graphs, graph-based approaches have achieved impressive performance in various biomedical applications. Most existing methods tend to define the adjacency matrix among samples manually…

机器学习 · 计算机科学 2021-07-02 Shuai Zheng , Zhenfeng Zhu , Zhizhe Liu , Zhenyu Guo , Yang Liu , Yao Zhao

Training a neural network with a large labeled dataset is still a dominant paradigm in computational histopathology. However, obtaining such exhaustive manual annotations is often expensive, laborious, and prone to inter and Intra-observer…

计算机视觉与模式识别 · 计算机科学 2021-11-03 Chetan L. Srinidhi , Seung Wook Kim , Fu-Der Chen , Anne L. Martel

Self-supervised learning has emerged as a powerful tool for pretraining deep networks on unlabeled data, prior to transfer learning of target tasks with limited annotation. The relevance between the pretraining pretext and target tasks is…

计算机视觉与模式识别 · 计算机科学 2024-04-09 Tianwei Zhang , Dong Wei , Mengmeng Zhu , Shi Gu , Yefeng Zheng

We present two approaches that use unlabeled data to improve sequence learning with recurrent networks. The first approach is to predict what comes next in a sequence, which is a conventional language model in natural language processing.…

机器学习 · 计算机科学 2015-11-05 Andrew M. Dai , Quoc V. Le

Federated learning aims to tackle the ``isolated data island" problem, where it trains a collective model from physically isolated clients while safeguarding the privacy of users' data. However, supervised federated learning necessitates…

人工智能 · 计算机科学 2024-04-18 Hao Yan , Yuhong Guo

Semi-supervised learning (SSL) alleviates the cost of data labeling process by exploiting unlabeled data and has achieved promising results. Meanwhile, with the development of large foundation models, exploiting pre-trained models becomes a…

机器学习 · 计算机科学 2025-10-28 Song-Lin Lv , Rui Zhu , Tong Wei , Yu-Feng Li , Lan-Zhe Guo

Domain adaptation for large neural language models (NLMs) is coupled with massive amounts of unstructured data in the pretraining phase. In this study, however, we show that pretrained NLMs learn in-domain information more effectively and…

计算与语言 · 计算机科学 2022-08-30 Shahriar Golchin , Mihai Surdeanu , Nazgol Tavabi , Ata Kiapour

Machine learning (ML) applied to routine patient monitoring within intensive care units (ICUs) has the potential to improve care by providing clinicians with novel insights into each patient's health and expected response to interventions.…

信号处理 · 电气工程与系统科学 2024-06-26 Thomas Kite , Uzair Tahamid Siam , Brian Ayers , Nicholas Houstis , Aaron D Aguirre

Pre-trained transformer language models (LMs) have in recent years become the dominant paradigm in applied NLP. These models have achieved state-of-the-art performance on tasks such as information extraction, question answering, sentiment…

计算与语言 · 计算机科学 2025-04-14 Aidan Mannion , Thierry Chevalier , Didier Schwab , Lorraine Geouriot

Although machine learning has become a powerful tool to augment doctors in clinical analysis, the immense amount of labeled data that is necessary to train supervised learning approaches burdens each development task as time and resource…

Self-supervised pre-training of transformer models has revolutionized NLP applications. Such pre-training with language modeling objectives provides a useful initial point for parameters that generalize well to new tasks with fine-tuning.…

计算与语言 · 计算机科学 2020-11-17 Trapit Bansal , Rishikesh Jha , Tsendsuren Munkhdalai , Andrew McCallum

Medical image-language pre-training aims to align medical images with clinically relevant text to improve model performance on various downstream tasks. However, existing models often struggle with the variability and ambiguity inherent in…

计算机视觉与模式识别 · 计算机科学 2025-07-30 Shreyank N Gowda , Ruichi Zhang , Xiao Gu , Ying Weng , Lu Yang

Recent advancements in computational chemistry have leveraged the power of trans-former-based language models, such as MoLFormer, pre-trained using a vast amount of simplified molecular-input line-entry system (SMILES) sequences, to…

生物大分子 · 定量生物学 2024-11-05 Tianhao Peng , Yuchen Li , Xuhong Li , Jiang Bian , Zeke Xie , Ning Sui , Shahid Mumtaz , Yanwu Xu , Linghe Kong , Haoyi Xiong

Graph pre-training has been concentrated on graph-level tasks involving small graphs (e.g., molecular graphs) or learning node representations on a fixed graph. Extending graph pre-trained models to web-scale graphs with billions of nodes…

机器学习 · 计算机科学 2025-11-07 Yufei He , Zhenyu Hou , Yukuo Cen , Jun Hu , Feng He , Xu Cheng , Jie Tang , Bryan Hooi

Predicting drug response in patients from preclinical data remains a major challenge in precision oncology due to the substantial biological gap between in vitro cell lines and patient tumors. Rather than aiming to improve absolute in vitro…

机器学习 · 计算机科学 2026-03-18 Camille Jimenez Cortes , Philippe Lalanda , German Vega

Self-supervised learning (SSL) enables label efficient training for machine learning models. This is essential for domains such as medical imaging, where labels are costly and time-consuming to curate. However, the most effective supervised…

计算机视觉与模式识别 · 计算机科学 2023-05-16 Cara Van Uden , Jeremy Irvin , Mars Huang , Nathan Dean , Jason Carr , Andrew Ng , Curtis Langlotz

Recent advances in unsupervised learning have shown that unsupervised pre-training, followed by fine-tuning, can improve model generalization. However, a rigorous understanding of how the representation function learned on an unlabeled…

机器学习 · 计算机科学 2024-03-12 Yuyang Deng , Junyuan Hong , Jiayu Zhou , Mehrdad Mahdavi

Large pre-trained models have been vital in recent advancements in domains like language and vision, making model training for individual downstream tasks more efficient and provide superior performance. However, tackling time-series…

机器学习 · 计算机科学 2024-12-06 Harshavardhan Kamarthi , B. Aditya Prakash

In this work, we investigate unsupervised representation learning on medical time series, which bears the promise of leveraging copious amounts of existing unlabeled data in order to eventually assist clinical decision making. By evaluating…

机器学习 · 计算机科学 2018-12-04 Xinrui Lyu , Matthias Hueser , Stephanie L. Hyland , George Zerveas , Gunnar Raetsch

Current 3D semi-supervised segmentation methods face significant challenges such as limited consideration of contextual information and the inability to generate reliable pseudo-labels for effective unsupervised data use. To address these…

计算机视觉与模式识别 · 计算机科学 2023-11-22 Sanaz Karimijafarbigloo , Reza Azad , Yury Velichko , Ulas Bagci , Dorit Merhof