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Cancer survival prediction is important for developing personalized treatments and inducing disease-causing mechanisms. Multi-omics data integration is attracting widespread interest in cancer research for providing information for…

基因组学 · 定量生物学 2022-07-12 Xing Wu , Qiulian Fang

We explore the use of Vector Quantized Variational AutoEncoder (VQ-VAE) models for large scale image generation. To this end, we scale and enhance the autoregressive priors used in VQ-VAE to generate synthetic samples of much higher…

机器学习 · 计算机科学 2019-06-04 Ali Razavi , Aaron van den Oord , Oriol Vinyals

While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…

机器学习 · 计算机科学 2019-07-15 Qingyu Zhao , Ehsan Adeli , Nicolas Honnorat , Tuo Leng , Kilian M. Pohl

Estimation of uncertainty in deep learning models is of vital importance, especially in medical imaging, where reliance on inference without taking into account uncertainty could lead to misdiagnosis. Recently, the probabilistic Variational…

机器学习 · 计算机科学 2020-10-20 Haleh Akrami , Anand A. Joshi , Sergul Aydore , Richard M. Leahy

Lung cancer is responsible for 21% of cancer deaths in the UK and five-year survival rates are heavily influenced by the stage the cancer was identified at. Recent studies have demonstrated the capability of AI methods for accurate and…

计算机视觉与模式识别 · 计算机科学 2023-11-28 Benjamin Keel , Aaron Quyn , David Jayne , Samuel D. Relton

Disentangled representation learning aims to represent the underlying generative factors of a dataset in a latent representation independently of one another. In our work, we propose a discrete variational autoencoder (VAE) based model…

计算机视觉与模式识别 · 计算机科学 2025-11-06 Gulcin Baykal , Melih Kandemir , Gozde Unal

Although semi-supervised variational autoencoder (SemiVAE) works in image classification task, it fails in text classification task if using vanilla LSTM as its decoder. From a perspective of reinforcement learning, it is verified that the…

计算与语言 · 计算机科学 2016-11-28 Weidi Xu , Haoze Sun , Chao Deng , Ying Tan

Classical supervised classification tasks search for a nonlinear mapping that maps each encoded feature directly to a probability mass over the labels. Such a learning framework typically lacks the intuition that encoded features from the…

计算机视觉与模式识别 · 计算机科学 2020-06-11 Cat P. Le , Yi Zhou , Jie Ding , Vahid Tarokh

Recent state-of-the-art autoencoder based generative models have an encoder-decoder structure and learn a latent representation with a pre-defined distribution that can be sampled from. Implementing the encoder networks of these models in a…

机器学习 · 计算机科学 2020-05-11 D. T. Braithwaite , M. O'Connor , W. B. Kleijn

We present a Split Vector Quantized Variational Autoencoder (SVQ-VAE) architecture using a split vector quantizer for NTTS, as an enhancement to the well-known Variational Autoencoder (VAE) and Vector Quantized Variational Autoencoder…

声音 · 计算机科学 2023-09-15 Marek Strong , Jonas Rohnke , Antonio Bonafonte , Mateusz Łajszczak , Trevor Wood

Image generative models can learn the distributions of the training data and consequently generate examples by sampling from these distributions. However, when the training dataset is corrupted with outliers, generative models will likely…

机器学习 · 计算机科学 2022-09-21 Chieh-Hsin Lai , Dongmian Zou , Gilad Lerman

Artificial Intelligence (AI) has the potential to revolutionize diagnosis and segmentation in medical imaging. However, development and clinical implementation face multiple challenges including limited data availability, lack of…

图像与视频处理 · 电气工程与系统科学 2025-01-22 Zelong Liu , Andrew Tieu , Nikhil Patel , Georgios Soultanidis , Louisa Deyer , Ying Wang , Sean Huver , Alexander Zhou , Yunhao Mei , Zahi A. Fayad , Timothy Deyer , Xueyan Mei

Motivation: Despite advances in the computational analysis of high-throughput molecular profiling assays (e.g. transcriptomics), a dichotomy exists between methods that are simple and interpretable, and ones that are complex but with lower…

机器学习 · 计算机科学 2023-06-12 Pedro Henrique da Costa Avelar , Min Wu , Sophia Tsoka

Vector-quantized autoencoders deliver high-fidelity latents but suffer inherent flaws: the quantizer is non-differentiable, requires straight-through hacks, and is prone to collapse. We address these issues at the root by replacing VQ with…

机器学习 · 计算机科学 2026-02-24 Hao Lu , Onur C. Koyun , Yongxin Guo , Zhengjie Zhu , Abbas Alili , Metin Nafi Gurcan

In this paper, we seek a clinically-relevant latent code for representing the spectrum of macular disease. Towards this end, we construct retina-VAE, a variational autoencoder-based model that accepts a patient profile vector (pVec) as…

图像与视频处理 · 电气工程与系统科学 2019-07-12 Stephen G. Odaibo

In this paper, we introduce a Variational Autoencoder (VAE) based training approach that can compress and decompress cancer pathology slides at a compression ratio of 1:512, which is better than the previously reported state of the art…

While most frontier models still use deterministic frequency-based tokenization algorithms such as byte-pair encoding (BPE), there has been significant recent work to design learned neural tokenizers. However, these schemes generally add to…

机器学习 · 计算机科学 2025-12-29 Theo Datta , Kayla Huang , Sham Kakade , David Brandfonbrener

Understanding the structure of complex, nonstationary, high-dimensional time-evolving signals is a central challenge in scientific data analysis. In many domains, such as speech and biomedical signal processing, the ability to learn…

机器学习 · 计算机科学 2026-01-13 Ioannis Ziogas , Aamna Al Shehhi , Ahsan H. Khandoker , Leontios J. Hadjileontiadis

Recent analysis identified distinct genomic subtypes of lower-grade glioma tumors which are associated with shape features. In this study, we propose a fully automatic way to quantify tumor imaging characteristics using deep learning-based…

图像与视频处理 · 电气工程与系统科学 2019-06-11 Mateusz Buda , Ashirbani Saha , Maciej A Mazurowski

We present a novel application of Vector quantised variational autoencoders (VQ-VAEs) to deep 1.28 GHz radio continuum images taken from the MeerKAT Galaxy Cluster Legacy Survey (MGCLS).VQ-VAEs are deep learning models widely used in modern…

天体物理仪器与方法 · 物理学 2026-01-21 Fernando L. Ventura , Kshitij Thorat , Anna Bosman , Roger Deane , Christopher Cleghorn