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In machine learning larger databases are usually associated with higher classification accuracy due to better generalization. This generalization may lead to non-optimal classifiers in some medical applications with highly variable…

图像与视频处理 · 电气工程与系统科学 2024-03-13 Michael Götz , Christian Weber , Christoph Kolb , Klaus Maier-Hein

Recently neural networks and multiple instance learning are both attractive topics in Artificial Intelligence related research fields. Deep neural networks have achieved great success in supervised learning problems, and multiple instance…

机器学习 · 统计学 2020-04-08 Xinggang Wang , Yongluan Yan , Peng Tang , Xiang Bai , Wenyu Liu

Machine learning (ML) holds great potential to advance anomaly detection (AD) in chemical processes. However, the development of ML-based methods is hindered by the lack of openly available experimental data. To address this gap, we have…

Digitizing pathological images into gigapixel Whole Slide Images (WSIs) has opened new avenues for Computational Pathology (CPath). As positive tissue comprises only a small fraction of gigapixel WSIs, existing Multiple Instance Learning…

计算机视觉与模式识别 · 计算机科学 2025-09-16 Wenhao Tang , Sheng Huang , Heng Fang , Fengtao Zhou , Bo Liu , Qingshan Liu

Predicting patient features from single-cell data can help identify cellular states implicated in health and disease. Linear models and average cell type expressions are typically favored for this task for their efficiency and robustness,…

机器学习 · 计算机科学 2024-03-11 Jan P. Engelmann , Alessandro Palma , Jakub M. Tomczak , Fabian J. Theis , Francesco Paolo Casale

We propose a novel framework to classify large-scale time series data with long duration. Long time seriesclassification (L-TSC) is a challenging problem because the dataoften contains a large amount of irrelevant information to…

人工智能 · 计算机科学 2021-11-23 Yuansheng Zhu , Weishi Shi , Deep Shankar Pandey , Yang Liu , Xiaofan Que , Daniel E. Krutz , Qi Yu

Acute Lymphoblastic Leukemia (ALL) is one of the most common types of childhood blood cancer. The quick start of the treatment process is critical to saving the patient's life, and for this reason, early diagnosis of this disease is…

计算机视觉与模式识别 · 计算机科学 2025-03-07 Amirhossein Askari Farsangi , Ali Sharifi-Zarchi , Mohammad Hossein Rohban

Multiple Instance Learning (MIL) is a cornerstone approach in computational pathology (CPath) for generating clinically meaningful slide-level embeddings from gigapixel tissue images. However, MIL often struggles with small, weakly…

计算机视觉与模式识别 · 计算机科学 2025-06-12 Daniel Shao , Richard J. Chen , Andrew H. Song , Joel Runevic , Ming Y. Lu , Tong Ding , Faisal Mahmood

Acute Myeloid Leukemia (AML) is one of the most aggressive types of hematological neoplasm. To support the specialists' decision about the appropriate therapy, patients with AML receive a prognostic of outcomes according to their…

机器学习 · 计算机科学 2024-05-30 Jade M. Almeida , Giovanna A. Castro , João A. Machado-Neto , Tiago A. Almeida

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

计算机视觉与模式识别 · 计算机科学 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

Combining the increasing availability and abundance of healthcare data and the current advances in machine learning methods have created renewed opportunities to improve clinical decision support systems. However, in healthcare risk…

机器学习 · 统计学 2021-06-17 Zidi Xiu , Chenyang Tao , Michael Gao , Connor Davis , Benjamin A. Goldstein , Ricardo Henao

Incipient anomalies present milder symptoms compared to severe ones, and are more difficult to detect and diagnose due to their close resemblance to normal operating conditions. The lack of incipient anomaly examples in the training data…

机器学习 · 计算机科学 2020-08-21 Baihong Jin , Yingshui Tan , Albert Liu , Xiangyu Yue , Yuxin Chen , Alberto Sangiovanni Vincentelli

Attention-based multiple instance learning (AMIL) algorithms have proven to be successful in utilizing gigapixel whole-slide images (WSIs) for a variety of different computational pathology tasks such as outcome prediction and cancer…

This paper attacks an emerging challenge of multi-modal retinal disease recognition. Given a multi-modal case consisting of a color fundus photo (CFP) and an array of OCT B-scan images acquired during an eye examination, we aim to build a…

计算机视觉与模式识别 · 计算机科学 2021-09-28 Xirong Li , Yang Zhou , Jie Wang , Hailan Lin , Jianchun Zhao , Dayong Ding , Weihong Yu , Youxin Chen

Multiple Instance Learning (MIL) has emerged as the best solution for Whole Slide Image (WSI) classification. It consists of dividing each slide into patches, which are treated as a bag of instances labeled with a global label. MIL includes…

计算机视觉与模式识别 · 计算机科学 2025-05-05 Ali Mammadov , Loic Le Folgoc , Julien Adam , Anne Buronfosse , Gilles Hayem , Guillaume Hocquet , Pietro Gori

Multiple instance learning (MIL) has been increasingly used in the classification of histopathology whole slide images (WSIs). However, MIL approaches for this specific classification problem still face unique challenges, particularly those…

计算机视觉与模式识别 · 计算机科学 2022-03-24 Hongrun Zhang , Yanda Meng , Yitian Zhao , Yihong Qiao , Xiaoyun Yang , Sarah E. Coupland , Yalin Zheng

Multi-instance learning (MIL) is a widely-applied technique in practical applications that involve complex data structures. MIL can be broadly categorized into two types: traditional methods and those based on deep learning. These…

人工智能 · 计算机科学 2023-04-25 Yu-Xuan Zhang , Zhengchun Zhou , Xingxing He , Avik Ranjan Adhikary , Bapi Dutta

Identification of abnormalities in red blood cells (RBC) is key to diagnosing a range of medical conditions from anaemia to liver disease. Currently this is done manually, a time-consuming and subjective process. This paper presents an…

计算机视觉与模式识别 · 计算机科学 2021-06-02 Annika Wong , Nantheera Anantrasirichai , Thanarat H. Chalidabhongse , Duangdao Palasuwan , Attakorn Palasuwan , David Bull

Breast cancer prediction models for mammography assume that annotations are available for individual images or regions of interest (ROIs), and that there is a fixed number of images per patient. These assumptions do not hold in real…

计算机视觉与模式识别 · 计算机科学 2024-10-22 Shreyasi Pathak , Jörg Schlötterer , Jeroen Geerdink , Jeroen Veltman , Maurice van Keulen , Nicola Strisciuglio , Christin Seifert

Traditional supervised learning tasks require a label for every instance in the training set, but in many real-world applications, labels are only available for collections (bags) of instances. This problem setting, known as multiple…

计算机视觉与模式识别 · 计算机科学 2023-05-23 Georg Wölflein , Lucie Charlotte Magister , Pietro Liò , David J. Harrison , Ognjen Arandjelović