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Bayesian models provide a framework for probabilistic modelling of complex datasets. However, many of such models are computationally demanding especially in the presence of large datasets. On the other hand, in sensor network applications,…

机器学习 · 计算机科学 2015-07-06 Behnam Babagholami-Mohamadabadi , Sejong Yoon , Vladimir Pavlovic

Rooted in genetics, human complex diseases are largely influenced by environmental factors. Existing literature has shown the power of integrative gene-environment interaction analysis by considering the joint effect of environmental…

统计方法学 · 统计学 2022-08-26 Jingyi Zhang , Xu Liu , Honglang Wang , Yuehua Cui

Markov Chain Monte Carlo (MCMC) methods are a popular technique in Bayesian statistical modeling. They have long been used to obtain samples from posterior distributions, but recent research has focused on the scalability of these…

统计方法学 · 统计学 2016-02-02 Nicholas A. Johnson , Frank O. Kuehnel , Ali Nasiri Amini

Envelope models provide a sufficient dimension reduction framework for multivariate regression analysis. Bayesian inference for these models has been developed primarily using Markov chain Monte Carlo (MCMC) methods. Specifically, Gibbs…

统计方法学 · 统计学 2026-03-03 Seunghyeon Kim , Kwangmin Lee , Yeonhee Park

Variational Autoencoders (VAEs) are a popular generative model, but one in which conditional inference can be challenging. If the decomposition into query and evidence variables is fixed, conditional VAEs provide an attractive solution. To…

机器学习 · 统计学 2018-10-05 Ga Wu , Justin Domke , Scott Sanner

Although the Bayesian paradigm offers a formal framework for estimating the entire probability distribution over uncertain parameters, its online implementation can be challenging due to high computational costs. We suggest the Adaptive…

机器学习 · 计算机科学 2023-10-23 Pedram Agand , Mo Chen , Hamid D. Taghirad

There is wide interest in studying how the distribution of a continuous response changes with a predictor. We are motivated by environmental applications in which the predictor is the dose of an exposure and the response is a health…

统计方法学 · 统计学 2018-05-10 Antonio Canale , Daniele Durante , David Dunson

We introduce inferential methods for prediction based on functional random effects in generalized functional mixed effects models. This is similar to the inference for random effects in generalized linear mixed effects models (GLMMs), but…

统计方法学 · 统计学 2025-01-15 Xinkai Zhou , Erjia Cui , Joseph Sartini , Ciprian Crainiceanu

The application of the Markov chain to modeling agricultural succession is well known. In most cases, the main problem is the inference of the model, i.e. the estimation of the transition matrix. In this work we present methods to estimate…

Bayesian inference promises to ground and improve the performance of deep neural networks. It promises to be robust to overfitting, to simplify the training procedure and the space of hyperparameters, and to provide a calibrated measure of…

机器学习 · 计算机科学 2019-08-12 Jonathan Heek , Nal Kalchbrenner

Structured additive distributional regression models offer a versatile framework for estimating complete conditional distributions by relating all parameters of a parametric distribution to covariates. Although these models efficiently…

统计方法学 · 统计学 2023-11-14 Jana Kleinemeier , Nadja Klein

Despite the recent success in probabilistic modeling and their applications, generative models trained using traditional inference techniques struggle to adapt to new distributions, even when the target distribution may be closely related…

机器学习 · 计算机科学 2019-09-17 Mike Wu , Kristy Choi , Noah Goodman , Stefano Ermon

Global variational approximation methods in graphical models allow efficient approximate inference of complex posterior distributions by using a simpler model. The choice of the approximating model determines a tradeoff between the…

人工智能 · 计算机科学 2013-01-14 Tal El-Hay , Nir Friedman

Variational regression methods are an increasingly popular tool for their efficient estimation of complex. Given the mixed model representation of penalized effects, additive regression models with smoothed effects and scalar-on-function…

统计方法学 · 统计学 2024-06-13 Mark J. Meyer , Junyi Wei

Statistical inference in evolutionary models with site-dependence is a long-standing challenge in phylogenetics and computational biology. We consider the problem of approximating marginal sequence likelihoods under dependent-site models of…

统计计算 · 统计学 2025-11-12 Joseph Mathews , Scott C. Schmidler

Motivated by examples from genetic association studies, this paper considers the model selection problem in a general complex linear model system and in a Bayesian framework. We discuss formulating model selection problems and incorporating…

统计方法学 · 统计学 2014-03-14 Xiaoquan Wen

We describe a regularized regression model for the selection of gene-environment (GxE) interactions. The model focuses on a single environmental exposure and induces a main-effect-before-interaction hierarchical structure. We propose an…

统计方法学 · 统计学 2022-02-08 Natalia Zemlianskaia , W. James Gauderman , Juan Pablo Lewinger

Several statistical models used in genome-wide prediction assume independence of marker allele substitution effects, but it is known that these effects might be correlated. In statistics, graphical models have been identified as a useful…

定量方法 · 定量生物学 2017-04-13 Carlos Alberto Martínez , Kshitij Khare , Syed Rahman , Mauricio A. Elzo

The quality of generalized linear models (GLMs), frequently used by insurance companies, depends on the choice of interacting variables. The search for interactions is time-consuming, especially for data sets with a large number of…

机器学习 · 统计学 2025-05-21 Yevhen Havrylenko , Julia Heger

High-dimensional variable selection, with many more covariates than observations, is widely documented in standard regression models, but there are still few tools to address it in non-linear mixed-effects models where data are collected…