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Computer-aided early diagnosis of Alzheimer's disease (AD) and its prodromal form mild cognitive impairment (MCI) based on structure Magnetic Resonance Imaging (sMRI) has provided a cost-effective and objective way for early prevention and…

图像与视频处理 · 电气工程与系统科学 2021-11-16 Xin Zhang , Liangxiu Han , Wenyong Zhu , Liang Sun , Daoqiang Zhang

The early detection of Alzheimer's Disease is imperative to ensure early treatment and improve patient outcomes. There has consequently been extenstive research into detecting AD and its intermediate phase, mild cognitive impairment (MCI).…

图像与视频处理 · 电气工程与系统科学 2024-01-17 Jamie Vo , Naeha Sharif , Ghulam Mubashar Hassan

Early and accurate diagnosis of Alzheimer's disease (AD) and its prodromal period mild cognitive impairment (MCI) is essential for the delayed disease progression and the improved quality of patients'life. The emerging computer-aided…

图像与视频处理 · 电气工程与系统科学 2021-07-29 Fan Zhang , Bo Pan , Pengfei Shao , Peng Liu , Shuwei Shen , Peng Yao , Ronald X. Xu

Progressive cognitive decline spanning across decades is characteristic of Alzheimer's disease (AD). Various predictive models have been designed to realize its early onset and study the long-term trajectories of cognitive test scores…

Alzheimer's disease (AD) is a prevalent neurodegenerative disorder that progressively impairs memory, decision-making, and overall cognitive function. As AD is irreversible, early prediction is critical for timely intervention and…

计算机视觉与模式识别 · 计算机科学 2025-12-01 Mahdieh Behjat Khatooni , Mohsen Soryani

Multi-modal biological, imaging, and neuropsychological markers have demonstrated promising performance for distinguishing Alzheimer's disease (AD) patients from cognitively normal elders. However, it remains difficult to early predict when…

计算机视觉与模式识别 · 计算机科学 2019-01-08 Hongming Li , Yong Fan

Introduction: It is challenging at baseline to predict when and which individuals who meet criteria for mild cognitive impairment (MCI) will ultimately progress to Alzheimer's disease (AD) dementia. Methods: A deep learning method is…

计算机视觉与模式识别 · 计算机科学 2019-04-17 Hongming Li , Mohamad Habes , David A. Wolk , Yong Fan

Unveiling pathological brain changes associated with Alzheimer's disease (AD) is a challenging task especially that people do not show symptoms of dementia until it is late. Over the past years, neuroimaging techniques paved the way for…

定量方法 · 定量生物学 2018-08-07 Mayssa Soussia , Islem Rekik

Alzheimer's disease (AD) is the most common age-related dementia. Mild cognitive impairment (MCI) is the early stage of cognitive decline before AD. It is crucial to predict the MCI-to-AD conversion for precise management, which remains…

图像与视频处理 · 电气工程与系统科学 2022-03-10 Yiran Wei , Stephen J. Price , Carola-Bibiane Schönlieb , Chao Li

Alzheimer's disease (AD) is an irreversible devastative neurodegenerative disorder associated with progressive impairment of memory and cognitive functions. Its early diagnosis is crucial for the development of possible future treatment…

计算机视觉与模式识别 · 计算机科学 2020-04-07 Ahsan Bin Tufail , Qiu-Na Zhang , Yong-Kui Ma

Alzheimer's disease (AD) progresses through distinct stages, from early mild cognitive impairment (EMCI) to late mild cognitive impairment (LMCI) and eventually to AD. Accurate identification of these stages, especially distinguishing LMCI…

计算机视觉与模式识别 · 计算机科学 2025-01-13 Aswini Kumar Patra , Soraisham Elizabeth Devi , Tejashwini Gajurel

Alzheimer's disease is a progressive, neurodegenerative disorder that causes memory loss and cognitive decline. While there has been extensive research in applying deep learning models to Alzheimer's prediction tasks, these models remain…

计算机视觉与模式识别 · 计算机科学 2025-09-15 Emily Kaczmarek , Justin Szeto , Brennan Nichyporuk , Tal Arbel

Alzheimer's Disease (AD) is a progressive disease preceded by Mild Cognitive Impairment (MCI). Early detection of AD is crucial for making treatment decisions. However, most of the literature on computer-assisted detection of AD focuses on…

图像与视频处理 · 电气工程与系统科学 2023-09-15 Misgina Tsighe Hagos , Niamh Belton , Ronan P. Killeen , Kathleen M. Curran , Brian Mac Namee

The application of machine learning algorithms to the diagnosis and analysis of Alzheimer's disease (AD) from multimodal neuroimaging data is a current research hotspot. It remains a formidable challenge to learn brain region information…

图像与视频处理 · 电气工程与系统科学 2022-08-11 Yongcheng Zong , Changhong Jing , Qiankun Zuo

Nowadays, a lot of scientific efforts are concentrated on the diagnosis of Alzheimer's Disease (AD) applying deep learning methods to neuroimaging data. Even for 2017, there were published more than a hundred papers dedicated to AD…

机器学习 · 计算机科学 2018-07-31 Yaroslav Shmulev , Mikhail Belyaev

Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Amnestic mild cognitive impairment (MCI) is a common first symptom before the conversion to clinical impairment where the individual becomes unable to perform activities…

计算机视觉与模式识别 · 计算机科学 2017-10-16 Donghuan Lu , Karteek Popuri , Weiguang Ding , Rakesh Balachandar , Mirza Faisal Beg

Computer-aided early diagnosis of Alzheimers Disease (AD) and its prodromal form, Mild Cognitive Impairment (MCI), has been the subject of extensive research in recent years. Some recent studies have shown promising results in the AD and…

计算机视觉与模式识别 · 计算机科学 2018-01-19 Alexander Khvostikov , Karim Aderghal , Jenny Benois-Pineau , Andrey Krylov , Gwenaelle Catheline

Mild cognitive impairment (MCI) is a high-risk dementia condition which progresses to probable Alzheimer's disease (AD) at approximately 10% to 15% per year. Characterization of group-level differences between two subtypes of MCI - stable…

神经元与认知 · 定量生物学 2021-06-15 Lu Zhang , Xiaowei Yu , Yanjun Lyu , Li Wang , Dajiang Zhu

The prediction of subjects with mild cognitive impairment (MCI) who will progress to Alzheimer's disease (AD) is clinically relevant, and may above all have a significant impact on accelerate the development of new treatments. In this…

图像与视频处理 · 电气工程与系统科学 2019-07-16 Kilian Hett , Vinh-Thong Ta , José V. Manjón , Pierrick Coupé

The so-called Mild Cognitive Impairment (MCI) or cognitive loss appears in a previous stage before Alzheimer's Disease (AD), but it does not seem sufficiently severe to interfere in independent abilities of daily life, so it usually does…

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