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A common approach to analyze a covariate-sample count matrix, an element of which represents how many times a covariate appears in a sample, is to factorize it under the Poisson likelihood. We show its limitation in capturing the tendency…

统计方法学 · 统计学 2017-10-06 Mingyuan Zhou

The intricate interplay between host organisms and their gut microbiota has catalyzed research into the microbiome's role in disease, shedding light on novel aspects of disease pathogenesis. However, the mechanisms through which the…

统计方法学 · 统计学 2024-02-20 Lei Fang , Yue Wang , Chenglong Ye

Survival analysis is an important area of medical research, yet existing models often struggle to balance simplicity with flexibility. Simple models require minimal adjustments but come with strong assumptions, while more flexible models…

统计方法学 · 统计学 2025-08-22 Peter Knaus , Daniel Winkler , Sebastian F. Schoppmann , Gerd Jomrich

Clinical investigators are increasingly interested in discovering computational biomarkers from short-term longitudinal omics data sets. This work focuses on Bayesian regression and variable selection for longitudinal omics datasets, which…

统计方法学 · 统计学 2025-05-20 Livia Popa , Sumanta Basu , Myung Hee Lee , Martin T. Wells

A key problem in computational sustainability is to understand the distribution of species across landscapes over time. This question gives rise to challenging large-scale prediction problems since (i) hundreds of species have to be…

Data increasingly take the form of a multi-way array, or tensor, in several biomedical domains. Such tensors are often incompletely observed. For example, we are motivated by longitudinal microbiome studies in which several timepoints are…

统计方法学 · 统计学 2024-11-01 Ziren Jiang , Gen Li , Eric F. Lock

Microbiome data are complex in nature, involving high dimensionality, compositionally, zero inflation, and taxonomic hierarchy. Compositional data reside in a simplex that does not admit the standard Euclidean geometry. Most existing…

统计方法学 · 统计学 2020-11-12 Gen Li , Yan Li , Kun Chen

During the semiconductor manufacturing process, predicting the yield of the semiconductor is an important problem. Early detection of defective product production in the manufacturing process can save huge production cost. The data…

应用统计 · 统计学 2021-08-03 Sewon Park , Kyeongwon Lee , Da-Eun Jeong , Heung-Kook Ko , Jaeyong Lee

A fully Bayesian approach is proposed for ultrahigh-dimensional nonparametric additive models in which the number of additive components may be larger than the sample size, though ideally the true model is believed to include only a small…

统计方法学 · 统计学 2013-09-24 Zuofeng Shang , Ping Li

Multivariate matched proportions (MMP) data appears in a variety of contexts including post-market surveillance of adverse events in pharmaceuticals, disease classification, and agreement between care providers. It consists of multiple sets…

统计方法学 · 统计学 2023-05-08 Mark J. Meyer , Haobo Cheng , Katherine Hobbs Knutson

Modeling sparse count data, which arise across numerous scientific fields, presents significant statistical challenges. This chapter addresses these challenges in the context of infectious disease prediction, with a focus on predicting…

机器学习 · 统计学 2026-02-05 Edwin Fong , Lancelot F. James , Juho Lee

This paper introduces a rectified and renormalized Fisher-Bingham model for compositional data with zeros, motivated in part by the presence of zeros in microbiota studies. The approach represents compositions through a square-root…

统计方法学 · 统计学 2026-04-29 Eugene Han , Marahi Perez-Tamayo , Hannah D. Holscher , Ruoqing Zhu

Fossil-based palaeoclimate reconstruction is an important area of ecological science that has gained momentum in the backdrop of the global climate change debate. The hierarchical Bayesian paradigm provides an interesting platform for…

应用统计 · 统计学 2013-12-13 Sabyasachi Mukhopadhyay , Sourabh Bhattacharya

Gene-gene interactions are often regarded as playing significant roles in influencing variabilities of complex traits. Although much research has been devoted to this area, to date a comprehensive statistical model that addresses the…

应用统计 · 统计学 2018-04-18 Durba Bhattacharya , Sourabh Bhattacharya

Zero-inflated regression models have had wide application recently and have provenuseful in modeling data with many zeros. Zero-inflated Binomial (ZIB) regression model is an extension of the ordinary binomial distribution that takes into…

统计理论 · 数学 2021-05-04 Aba Diop , Demba Bocar Ba , Fatimata Lo

In all areas of human knowledge, datasets are increasing in both size and complexity, creating the need for richer statistical models. This trend is also true for economic data, where high-dimensional and nonlinear/nonparametric inference…

计量经济学 · 经济学 2021-12-23 Dimitris Korobilis , Kenichi Shimizu

Scientific practice typically involves repeatedly studying a system, each time trying to unravel a different perspective. In each study, the scientist may take measurements under different experimental conditions (interventions,…

机器学习 · 统计学 2014-03-11 Sofia Triantafillou , Ioannis Tsamardinos

We present a flexible Bayesian semiparametric mixed model for longitudinal data analysis in the presence of potentially high-dimensional categorical covariates. Building on a novel hidden Markov tensor decomposition technique, our proposed…

统计方法学 · 统计学 2022-08-05 Giorgio Paulon , Peter Müller , Abhra Sarkar

In real-world clinical settings, data distributions evolve over time, with a continuous influx of new, limited disease cases. Therefore, class incremental learning is of great significance, i.e., deep learning models are required to learn…

计算机视觉与模式识别 · 计算机科学 2024-09-13 Yifei Yao , Hanrong Zhang

We introduce a flexible and scalable class of Bayesian geostatistical models for discrete data, based on the class of nearest neighbor mixture transition distribution processes (NNMP), referred to as discrete NNMP. The proposed class…

统计方法学 · 统计学 2022-03-04 Xiaotian Zheng , Athanasios Kottas , Bruno Sansó