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When an exposure of interest is confounded by unmeasured factors, an instrumental variable (IV) can be used to identify and estimate certain causal contrasts. Identification of the marginal average treatment effect (ATE) from IVs relies on…

统计方法学 · 统计学 2023-10-02 Alexander W. Levis , Matteo Bonvini , Zhenghao Zeng , Luke Keele , Edward H. Kennedy

We propose the instrumental variable regime (IVR) method to estimate the causal effects of multiple sequential treatments. This method serves to address the problem of endogenous selections of sequential treatments. An IVR is a sequence of…

统计方法学 · 统计学 2017-02-21 Thai Pham , Weixin Chen

In observational studies, instrumental variables estimation is greatly utilized to identify causal effects. One of the key conditions for the instrumental variables estimator to be consistent is the exclusion restriction, which indicates…

统计方法学 · 统计学 2020-06-16 Gyuhyeong Goh , Jisang Yu

Causal structure learning from observational data remains a non-trivial task due to various factors such as finite sampling, unobserved confounding factors, and measurement errors. Constraint-based and score-based methods tend to suffer…

机器学习 · 计算机科学 2022-11-09 Rezaur Rashid , Jawad Chowdhury , Gabriel Terejanu

Causal representation learning seeks to recover latent factors that generate observational data through a mixing function. Needing assumptions on latent structures or relationships to achieve identifiability in general, prior works often…

人工智能 · 计算机科学 2025-09-24 Kwonho Kim , Heejeong Nam , Inwoo Hwang , Sanghack Lee

Mediation analysis is a strategy for understanding the mechanisms by which treatments or interventions affect later outcomes. Mediation analysis is frequently applied in randomized trial settings, but typically assumes: a) that randomized…

统计方法学 · 统计学 2021-12-30 Kara E. Rudolph , Nicholas Williams , Ivan Diaz

Causal discovery is a fundamental problem with applications spanning various areas in science and engineering. It is well understood that solely using observational data, one can only orient the causal graph up to its Markov equivalence…

机器学习 · 计算机科学 2024-10-29 Zihan Zhou , Muhammad Qasim Elahi , Murat Kocaoglu

The price elasticity of demand can be estimated from observational data using instrumental variables (IV). However, naive IV estimators may be inconsistent in settings with autocorrelated time series. We argue that causal time graphs can…

One of the most common mistakes made when performing data analysis is attributing causal meaning to regression coefficients. Formally, a causal effect can only be computed if it is identifiable from a combination of observational data and…

人工智能 · 计算机科学 2019-10-31 Daniel Kumor , Bryant Chen , Elias Bareinboim

A fundamental difficulty of causal learning is that causal models can generally not be fully identified based on observational data only. Interventional data, that is, data originating from different experimental environments, improves…

统计方法学 · 统计学 2021-11-04 Juan L. Gamella , Christina Heinze-Deml

Standard instrumental variables (IV) methods identify a Local Average Treatment Effect under monotonicity, which rules out defiers. In many empirical environments, however, distinct instruments may induce heterogeneous and even opposing…

计量经济学 · 经济学 2026-02-16 Johann Caro-Burnett

The increasing capture and analysis of large-scale longitudinal health data offer opportunities to improve healthcare and advance medical understanding. However, a critical gap exists between (a) -- the observation of patterns and…

人机交互 · 计算机科学 2025-08-26 Arran Zeyu Wang , David Borland , David Gotz

The advent of the big data era brought new opportunities and challenges to draw treatment effect in data fusion, that is, a mixed dataset collected from multiple sources (each source with an independent treatment assignment mechanism). Due…

人工智能 · 计算机科学 2022-12-08 Anpeng Wu , Kun Kuang , Ruoxuan Xiong , Minqing Zhu , Yuxuan Liu , Bo Li , Furui Liu , Zhihua Wang , Fei Wu

Causal gene networks model the flow of information within a cell, but reconstructing them from omics data is challenging because correlation does not imply causation. Combining genomics and transcriptomics data from a segregating population…

分子网络 · 定量生物学 2021-10-29 Adriaan-Alexander Ludl , Tom Michoel

At the heart of causal structure learning from observational data lies a deceivingly simple question: given two statistically dependent random variables, which one has a causal effect on the other? This is impossible to answer using…

机器学习 · 计算机科学 2020-10-13 Nikolaos Nikolaou , Konstantinos Sechidis

Causal inference is to estimate the causal effect in a causal relationship when intervention is applied. Precisely, in a causal model with binary interventions, i.e., control and treatment, the causal effect is simply the difference between…

机器学习 · 计算机科学 2022-07-19 Zhenyu Lu , Yurong Cheng , Mingjun Zhong , George Stoian , Ye Yuan , Guoren Wang

Algorithms for constraint-based causal discovery select graphical causal models among a space of possible candidates (e.g., all directed acyclic graphs) by executing a sequence of conditional independence tests. These may be used to inform…

统计方法学 · 统计学 2025-09-19 Ting-Hsuan Chang , Zijian Guo , Daniel Malinsky

The endogeneity issue is fundamentally important as many empirical applications may suffer from the omission of explanatory variables, measurement error, or simultaneous causality. Recently, \cite{hllt17} propose a "Deep Instrumental…

统计理论 · 数学 2020-05-01 Ruiqi Liu , Zuofeng Shang , Guang Cheng

Identifying the direct causes or causal parents of a target variable is crucial for scientific discovery. Focusing on linear models, the invariant prediction framework was built upon the invariance principle, namely, the conditional…

统计方法学 · 统计学 2023-07-19 Kang Du , Yu Xiang , Ilya Soloveychik

The Granular Instrumental Variables (GIV) methodology exploits panels with factor error structures to construct instruments to estimate structural time series models with endogeneity even after controlling for latent factors. We extend the…

计量经济学 · 经济学 2023-09-26 Saman Banafti , Tae-Hwy Lee