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Biomedical photoacoustic (PA) imaging is typically used to exploit absorption-based contrast in soft tissue at depths of several centimeters. When it is applied to measuring PA waves generated in the brain, the acoustic properties of the…

医学物理 · 物理学 2023-09-26 Thomas Kirchner , Claus Villringer , Jan Laufer

Acoustic impedance mismatches between soft tissues and bones are known to result in strong aberrations in optoacoustic and ultrasound images. Of particular importance are the severe distortions introduced by the human skull, impeding…

医学物理 · 物理学 2021-08-10 Xose Luis Dean-Ben , Daniel Razansky

Task-based functional magnetic resonance imaging (task fMRI) is a non-invasive technique that allows identifying brain regions whose activity changes when individuals are asked to perform a given task. This contributes to the understanding…

统计方法学 · 统计学 2021-03-17 Yasser Aleman-Gomez , Ana Arribas-Gil , Manuel Desco , Antonio Elias-Fernandez , Juan Romo

Functional magnetic resonance imaging (fMRI) is a non-invasive and in-vivo imaging technique essential for measuring brain activity. Functional connectivity is used to study associations between brain regions, either while study subjects…

应用统计 · 统计学 2024-03-26 Kun Meng , Ani Eloyan

Combining Functional MRI (fMRI) data across different subjects and datasets is crucial for many neuroscience tasks. Relying solely on shared anatomy for brain-to-brain mapping is inadequate. Existing functional transformation methods thus…

神经元与认知 · 定量生物学 2025-03-18 Navve Wasserman , Roman Beliy , Roy Urbach , Michal Irani

Transcranial photoacoustic computed tomography (PACT) is an emerging neuroimaging modality, but skull-induced aberrations can result in severe image artifacts if not compensated for during image reconstruction. The development of advanced…

Determining the brain perfusion is an important task for the diagnosis and treatment of vascular diseases such as occlusions and intracerebral haemorrhage. Even after successful diagnosis and treatment, there is a high risk of restenosis or…

Imaging the human brain vasculature with high spatial and temporal resolution remains challenging in the clinic today. Transcranial ultrasound is scarcely used for cerebrovascular imaging, due to low sensitivity and strong phase aberrations…

Four-dimensional ultrasound imaging of complex biological systems such as the brain is technically challenging because of the spatiotemporal sampling requirements. We present computational ultrasound imaging (cUSi), a new imaging method…

Photoacoustic (PA) waves are strongly distorted and attenuated in skull bone. To study these effects on PA imaging, we designed and 3D-printed tissue-mimicking phantoms of human skull. We present a comparison of results in phantom and ex…

医学物理 · 物理学 2025-02-18 Hannah Linde , Saskia Menzer , Jan Laufer , Thomas Kirchner

Photoacoustic (PA) imaging has the potential to revolutionize functional medical imaging in healthcare due to the valuable information on tissue physiology contained in multispectral photoacoustic measurements. Clinical translation of the…

A prospective study was performed on neurosurgical samples from 18 patients to evaluate the use of Full-Field Optical Coherence Tomography (FF-OCT) in brain tumor diagnosis. FF-OCT captures en face slices of tissue samples at 1\mum…

In recent years, the rapid development of neuroimaging technology has been providing many powerful tools for cognitive neuroscience research. Among them, the functional magnetic resonance imaging (fMRI), which has high spatial resolution,…

人机交互 · 计算机科学 2018-08-20 Yang Wang , Dongrui Wu

Every day, the human brain processes an immense volume of visual information, relying on intricate neural mechanisms to perceive and interpret these stimuli. Recent breakthroughs in functional magnetic resonance imaging (fMRI) have enabled…

计算机视觉与模式识别 · 计算机科学 2023-05-22 Matteo Ferrante , Furkan Ozcelik , Tommaso Boccato , Rufin VanRullen , Nicola Toschi

Photoacoustic computed tomography (PACT) is an emerging imaging modality that exploits optical contrast and ultrasonic detection principles to form images of the photoacoustically induced initial pressure distribution within tissue. The…

Functional magnetic resonance imaging (fMRI) is one of the most popular methods for studying the human brain. Task-related fMRI data processing aims to determine which brain areas are activated when a specific task is performed and is…

信号处理 · 电气工程与系统科学 2022-10-18 Paris A. Karakasis , Athanasios P. Liavas , Nicholas D. Sidiropoulos , Panagiotis G. Simos , Efrosini Papadaki

To date, brain imaging has largely relied on X-ray computed tomography and magnetic resonance angiography with limited spatial resolution and long scanning times. Fluorescence-based brain imaging in the visible and traditional near-infrared…

Photoacoustic imaging combines the high contrast of optical imaging with the deep penetration depth of ultrasonic imaging, showing great potential in cerebrovascular disease detection. However, the ultrasonic wave suffers strong attenuation…

医学物理 · 物理学 2025-09-08 Pengcheng Wan , Fan Zhang , Yuting Shen , Hulin Zhao , Xiran Cai , Xiaohua Feng , Fei Gao

In recent years, research on decoding brain activity based on functional magnetic resonance imaging (fMRI) has made remarkable achievements. However, constraint-free natural image reconstruction from brain activity is still a challenge. The…

计算机视觉与模式识别 · 计算机科学 2018-01-17 Chi Zhang , Kai Qiao , Linyuan Wang , Li Tong , Ying Zeng , Bin Yan

Recent advances in brain-vision decoding have driven significant progress, reconstructing with high fidelity perceived visual stimuli from neural activity, e.g., functional magnetic resonance imaging (fMRI), in the human visual cortex. Most…

计算机视觉与模式识别 · 计算机科学 2025-07-04 Le Xu , Qi Zhang , Qixian Zhang , Hongyun Zhang , Duoqian Miao , Cairong Zhao