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Single-molecule localization microscopy generates point clouds corresponding to fluorophore localizations. Spatial cluster identification and analysis of these point clouds are crucial for extracting insights about molecular organization.…

The Fast Fourier Transform (FFT) is widely used in applications such as MRI, CT, and interferometry; however, because of its dependence on uniformly sampled data, it requires the use of gridding techniques for practical implementation. The…

数值分析 · 数学 2025-12-22 Federico Achini , Paola Causin , Sara Vanini , Ke Chen , Simone Scacchi

Feature ranking and selection is a widely used approach in various applications of supervised dimensionality reduction in discriminative machine learning. Nevertheless there exists significant evidence on feature ranking and selection…

机器学习 · 计算机科学 2021-05-04 Ozan Ozdenizci , Deniz Erdogmus

Background: Multi-collimator proton minibeam radiation therapy (MC-pMBRT) has recently emerged as a versatile technique for dose shaping, enabling peak-valley dose patterns in organs-at-risk (OAR) while maintaining a uniform dose…

医学物理 · 物理学 2025-02-25 Nimita Shinde , Weijie Zhang , Yuting Lin , Hao Gao

We present BackboneLearn: an open-source software package and framework for scaling mixed-integer optimization (MIO) problems with indicator variables to high-dimensional problems. This optimization paradigm can naturally be used to…

机器学习 · 计算机科学 2023-11-27 Vassilis Digalakis , Christos Ziakas

In this paper, we present a new adaptive feature scaling scheme for ultrahigh-dimensional feature selection on Big Data. To solve this problem effectively, we first reformulate it as a convex semi-infinite programming (SIP) problem and then…

机器学习 · 计算机科学 2019-12-17 Mingkui Tan , Ivor W. Tsang , Li Wang

By removing irrelevant and redundant features, feature selection aims to find a good representation of the original features. With the prevalence of unlabeled data, unsupervised feature selection has been proven effective in alleviating the…

机器学习 · 计算机科学 2024-03-25 Ziyuan Lin , Deanna Needell

Among the most famous algorithms for solving classification problems are support vector machines (SVMs), which find a separating hyperplane for a set of labeled data points. In some applications, however, labels are only available for a…

最优化与控制 · 数学 2023-10-17 Jan Pablo Burgard , Maria Eduarda Pinheiro , Martin Schmidt

We consider a discrete optimization formulation for learning sparse classifiers, where the outcome depends upon a linear combination of a small subset of features. Recent work has shown that mixed integer programming (MIP) can be used to…

机器学习 · 统计学 2021-06-08 Antoine Dedieu , Hussein Hazimeh , Rahul Mazumder

Support Vector Machine (SVM) is a state-of-the-art classification method widely used in science and engineering due to its high accuracy, its ability to deal with high dimensional data, and its flexibility in modeling diverse sources of…

机器学习 · 计算机科学 2024-09-30 Xingfu Wu , Tupendra Oli , Justin H. Qian , Valerie Taylor , Mark C. Hersam , Vinod K. Sangwan

Support vector machines (SVM) and other kernel techniques represent a family of powerful statistical classification methods with high accuracy and broad applicability. Because they use all or a significant portion of the training data,…

机器学习 · 统计学 2023-01-31 Peter Mills

High dimensionality in datasets produced by microarray technology presents a challenge for Machine Learning (ML) algorithms, particularly in terms of dimensionality reduction and handling imbalanced sample sizes. To mitigate the explained…

The selection of Gaussian kernel parameters plays an important role in the applications of support vector classification (SVC). A commonly used method is the k-fold cross validation with grid search (CV), which is extremely time-consuming…

机器学习 · 计算机科学 2025-01-22 Linkai Luo , Qiaoling Yang , Hong Peng , Yiding Wang , Ziyang Chen

In order to identify one system (module) in an interconnected dynamic network, one typically has to solve a Multi-Input-Single-Output (MISO) identification problem that requires identification of all modules in the MISO setup. For…

系统与控制 · 电气工程与系统科学 2021-01-27 Karthik R. Ramaswamy , Giulio Bottegal , Paul M. J. Van den Hof

Kernel density estimation is a well known method involving a smoothing parameter (the bandwidth) that needs to be tuned by the user. Although this method has been widely used the bandwidth selection remains a challenging issue in terms of…

统计理论 · 数学 2019-02-05 Suzanne Varet , Claire Lacour , Pascal Massart , Vincent Rivoirard

A spectral mixture (SM) kernel is a flexible kernel used to model any stationary covariance function. Although it is useful in modeling data, the learning of the SM kernel is generally difficult because optimizing a large number of…

机器学习 · 统计学 2020-06-15 Yohan Jung , Kyungwoo Song , Jinkyoo Park

Support Vector Machines (SVMs) are powerful learners that have led to state-of-the-art results in various computer vision problems. SVMs suffer from various drawbacks in terms of selecting the right kernel, which depends on the image…

计算机视觉与模式识别 · 计算机科学 2014-03-31 Gemma Roig , Xavier Boix , Luc Van Gool

We address the Least Quantile of Squares (LQS) (and in particular the Least Median of Squares) regression problem using modern optimization methods. We propose a Mixed Integer Optimization (MIO) formulation of the LQS problem which allows…

统计计算 · 统计学 2014-11-20 Dimitris Bertsimas , Rahul Mazumder

Feature selection is an important preprocessing step for classification problems. It deals with selecting near optimal features in the original dataset. Feature selection is an NP-hard problem, so meta-heuristics can be more efficient than…

人工智能 · 计算机科学 2017-12-12 Majdi Mafarja , Seyedali Mirjalili

In the last few years, various types of machine learning algorithms, such as Support Vector Machine (SVM), Support Vector Regression (SVR), and Non-negative Matrix Factorization (NMF) have been introduced. The kernel approach is an…

机器学习 · 计算机科学 2022-12-16 Sajad Fathi Hafshejani , Zahra Moberfard