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Fluorescent calcium imaging provides a potentially powerful tool for inferring connectivity in neural circuits with up to thousands of neurons. However, a key challenge in using calcium imaging for connectivity detection is that current…

信息论 · 计算机科学 2014-09-05 Alyson K. Fletcher , Sundeep Rangan

In clinical practice, automatic analysis of electrocardiogram (ECG) is widely applied to identify irregular heart rhythms and other electrical anomalies of the heart, enabling timely intervention and potentially improving clinical outcomes.…

机器学习 · 计算机科学 2025-09-03 Zhangyue Shi , Zekai Wang , Yuxuan Li

Purpose: To apply a convolutional neural network (CNN) to develop a system that segments intensity calibration phantom regions in computed tomography (CT) images, and to test the system in a large cohort to evaluate its robustness. Methods:…

计算机视觉与模式识别 · 计算机科学 2020-12-22 Keisuke Uemura , Yoshito Otake , Masaki Takao , Mazen Soufi , Akihiro Kawasaki , Nobuhiko Sugano , Yoshinobu Sato

We develop a procedure for substantially improving the quality of segmented 3D micro-Computed Tomography (micro-CT) images of rocks with a Machine Learning (ML) Generative Model. The proposed model enhances the resolution eightfold (8x) and…

图像与视频处理 · 电气工程与系统科学 2025-01-14 Evgeny Ugolkov , Xupeng He , Hyung Kwak , Hussein Hoteit

Electroencephalogram (EEG) signals have gained widespread adoption in brain-computer interface (BCI) applications due to their non-invasive, low-cost, and relatively simple acquisition process. The demand for higher spatial resolution,…

神经元与认知 · 定量生物学 2025-08-21 Kartik Pandey , Arun Balasubramanian , Debasis Samanta

Cardiovascular diseases (CVD) remain a leading health concern and contribute significantly to global mortality rates. While clinical advancements have led to a decline in CVD mortality, accurately identifying individuals who could benefit…

图像与视频处理 · 电气工程与系统科学 2024-11-18 Minfeng Xu , Chen-Chen Fan , Yan-Jie Zhou , Wenchao Guo , Pan Liu , Jing Qi , Le Lu , Hanqing Chao , Kunlun He

Generative adversarial networks (GANs) have shown great success in applications such as image generation and inpainting. However, they typically require large datasets, which are often not available, especially in the context of prediction…

机器学习 · 计算机科学 2020-01-31 Daniel Stoller , Sebastian Ewert , Simon Dixon

Purpose: To assess the feasibility of deep learning-based high resolution synthetic CT generation from MRI scans of the lower arm for orthopedic applications. Methods: A conditional Generative Adversarial Network was trained to synthesize…

Weakly supervised disease classification of CT imaging suffers from poor localization owing to case-level annotations, where even a positive scan can hold hundreds to thousands of negative slices along multiple planes. Furthermore, although…

计算机视觉与模式识别 · 计算机科学 2020-11-03 Anindo Saha , Fakrul I. Tushar , Khrystyna Faryna , Vincent M. D'Anniballe , Rui Hou , Maciej A. Mazurowski , Geoffrey D. Rubin , Joseph Y. Lo

Reporting test-retest reliability using the intraclass correlation coefficient (ICC) has received increasing attention due to the criticisms of poor transparency and replicability in neuroimaging research, as well as many other biomedical…

统计方法学 · 统计学 2026-01-07 Yufeng Liu , Xiangfei Hong , Shanbao Tong

Computed tomography (CT) is a widely used non-invasive diagnostic method in various fields, and recent advances in deep learning have led to significant progress in CT image reconstruction. However, the lack of large-scale, open-access…

图像与视频处理 · 电气工程与系统科学 2024-12-12 Maximilian B. Kiss , Ander Biguri , Zakhar Shumaylov , Ferdia Sherry , K. Joost Batenburg , Carola-Bibiane Schönlieb , Felix Lucka

Accurate prediction of cardiovascular diseases remains imperative for early diagnosis and intervention, necessitating robust and precise predictive models. Recently, there has been a growing interest in multi-modal learning for uncovering…

计算机视觉与模式识别 · 计算机科学 2024-11-12 Francesco Girlanda , Olga Demler , Bjoern Menze , Neda Davoudi

Cellular Electron CryoTomography (CECT) is a 3D imaging technique that captures information about the structure and spatial organization of macromolecular complexes within single cells, in near-native state and at sub-molecular resolution.…

定量方法 · 定量生物学 2018-07-04 Kai Wen Wang , Xiangrui Zeng , Xiaodan Liang , Zhiguang Huo , Eric P. Xing , Min Xu

The presence of plaques in the coronary arteries is a major risk to the patients' life. In particular, non-calcified plaques pose a great challenge, as they are harder to detect and more likely to rupture than calcified plaques. While…

Colorectal cancer (CRC) grading is typically carried out by assessing the degree of gland formation within histology images. To do this, it is important to consider the overall tissue micro-environment by assessing the cell-level…

图像与视频处理 · 电气工程与系统科学 2019-09-04 Yanning Zhou , Simon Graham , Navid Alemi Koohbanani , Muhammad Shaban , Pheng-Ann Heng , Nasir Rajpoot

Accurate segmentation of the left ventricle myocardium in cardiac CT angiography (CCTA) is essential for e.g. the assessment of myocardial perfusion. Automatic deep learning methods for segmentation in CCTA might suffer from differences in…

计算机视觉与模式识别 · 计算机科学 2019-01-29 Steffen Bruns , Jelmer M. Wolterink , Robbert W. van Hamersvelt , Majd Zreik , Tim Leiner , Ivana Išgum

This paper proposes a novel approach based on conditional Generative Adversarial Networks (cGAN) for breast mass segmentation in mammography. We hypothesized that the cGAN structure is well-suited to accurately outline the mass area,…

Objectives: This study aims to characterize the dose-performance relationship for opportunistic CT and disentangle the contributions of segmentation failure and dose-dependent HU bias to performance degradation. Methods: Simulated low-dose…

Reconstruction kernels in computed tomography (CT) affect spatial resolution and noise characteristics, introducing systematic variability in quantitative imaging measurements such as emphysema quantification. Choosing an appropriate kernel…

Quantitative measures of dopamine transporter (DaT) uptake in caudate, putamen, and globus pallidus derived from DaT-single-photon emission computed tomography (SPECT) images are being investigated as biomarkers to diagnose, assess disease…