中文
相关论文

相关论文: Identifying Patient-Specific Root Causes of Diseas…

200 篇论文

Explaining artificial intelligence or machine learning models is increasingly important. To use such data-driven systems wisely we must understand how they interact with the world, including how they depend causally on data inputs. In this…

机器学习 · 计算机科学 2023-07-06 Joshua R. Loftus , Lucius E. J. Bynum , Sakina Hansen

Heart Disease has become one of the most serious diseases that has a significant impact on human life. It has emerged as one of the leading causes of mortality among the people across the globe during the last decade. In order to prevent…

机器学习 · 计算机科学 2022-06-08 Muhammad Salman Pathan , Avishek Nag , Muhammad Mohisn Pathan , Soumyabrata Dev

Poly-trees are singly connected causal networks in which variables may arise from multiple causes. This paper develops a method of recovering ply-trees from empirically measured probability distributions of pairs of variables. The method…

人工智能 · 计算机科学 2013-04-11 George Rebane , Judea Pearl

Consider the case that one observes a single time-series, where at each time t one observes a data record O(t) involving treatment nodes A(t), possible covariates L(t) and an outcome node Y(t). The data record at time t carries information…

统计理论 · 数学 2021-02-04 Mark J. van der Laan , Ivana Malenica

Parkinson's disease (PD) is a chronic and complex neurodegenerative disorder influenced by genetic, clinical, and lifestyle factors. Predicting this disease early is challenging because it depends on traditional diagnostic methods that face…

Causal inference has recently gained notable attention across various fields like biology, healthcare, and environmental science, especially within explainable artificial intelligence (xAI) systems, for uncovering the causal relationships…

机器学习 · 计算机科学 2025-01-13 Xiaofeng Xiao , Khawlah Alharbi , Pengyu Zhang , Hantang Qin , Xubo Yue

Causal modeling has long been an attractive topic for many researchers and in recent decades there has seen a surge in theoretical development and discovery algorithms. Generally discovery algorithms can be divided into two approaches:…

机器学习 · 统计学 2017-02-06 Ridho Rahmadi , Perry Groot , Marianne Heins , Hans Knoop , Tom Heskes

Causal effect estimation is a critical task in statistical learning that aims to find the causal effect on subjects by identifying causal links between a number of predictor (or, explanatory) variables and the outcome of a treatment. In a…

统计方法学 · 统计学 2024-11-26 Tathagata Basu , Matthias C. M. Troffaes

Causal models communicate our assumptions about causes and effects in real-world phe- nomena. Often the interest lies in the identification of the effect of an action which means deriving an expression from the observed probability…

机器学习 · 统计学 2018-06-20 Santtu Tikka , Juha Karvanen

We develop methodology for causal inference in observational studies when using propensity score subclassification on data constructed with probabilistic record linkage techniques. We focus on scenarios where covariates and binary treatment…

统计方法学 · 统计学 2018-04-03 Joan Heck Wortman , Jerome P. Reiter

In many clinical trials, individuals in different subgroups have experience differential treatment effects. This leads to individualized differences in treatment benefit. In this article, we introduce the general concept of predictive…

统计方法学 · 统计学 2018-07-11 Debashis Ghosh , Youngjoo Cho

Increasingly large electronic health records (EHRs) provide an opportunity to algorithmically learn medical knowledge. In one prominent example, a causal health knowledge graph could learn relationships between diseases and symptoms and…

应用统计 · 统计学 2019-10-04 Irene Y. Chen , Monica Agrawal , Steven Horng , David Sontag

Infectious diseases are caused by pathogenic microorganisms and can spread through different ways. Mathematical models and computational simulation have been used extensively to investigate the transmission and spread of infectious…

Many statistical methods have been proposed to estimate causal models in classical situations with fewer variables than observations (p<n, p: the number of variables and n: the number of observations). However, modern datasets including…

机器学习 · 统计学 2011-04-08 Shohei Shimizu , Takashi Washio , Aapo Hyvarinen , Seiya Imoto

Instrumental variable approaches have gained popularity for estimating causal effects in the presence of unmeasured confounders. However, the availability of instrumental variables in the primary dataset is often challenged due to stringent…

统计方法学 · 统计学 2026-03-31 Kang Shuai , Shanshan Luo , Wei Li , Yangbo He

The importance of clinical variables in the prognosis of the disease is explained using statistical correlation or machine learning (ML). However, the predictive importance of these variables may not represent their causal relationships…

机器学习 · 统计学 2025-06-04 Yina Hou , Shourav B. Rabbani , Liang Hong , Norou Diawara , Manar D. Samad

The automation of the medical evidence acquisition and diagnosis process has recently attracted increasing attention in order to reduce the workload of doctors and democratize access to medical care. However, most works proposed in the…

计算与语言 · 计算机科学 2022-10-14 Arsene Fansi Tchango , Rishab Goel , Julien Martel , Zhi Wen , Gaetan Marceau Caron , Joumana Ghosn

Heart disease continues to pose a critical worldwide health issue, more specifically in areas with insufficient access to healthcare infrastructure and diagnostic systems. Conventional diagnostic approaches often fall short in accurately…

A causal decomposition analysis allows researchers to determine whether the difference in a health outcome between two groups can be attributed to a difference in each group's distribution of one or more modifiable mediator variables. With…

统计方法学 · 统计学 2024-08-09 Melissa J. Smith , Leslie A. McClure , D. Leann Long

Learning-based signal processing systems increasingly support high-stakes medical decisions using heterogeneous biomedical signals, including medical images, physiological time series, and clinical records. Despite strong predictive…

信号处理 · 电气工程与系统科学 2026-03-02 Surajit Das , Maxine Tan