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Current Computer-Aided Diagnosis (CAD) methods mainly depend on medical images. The clinical information, which usually needs to be considered in practical clinical diagnosis, has not been fully employed in CAD. In this paper, we propose a…

图像与视频处理 · 电气工程与系统科学 2021-03-11 Songxiao Yang , Xiabi Liu , Zhongshu Zheng , Wei Wang , Xiaohong Ma

Computer-aided early diagnosis of Alzheimer's disease (AD) and its prodromal form mild cognitive impairment (MCI) based on structure Magnetic Resonance Imaging (sMRI) has provided a cost-effective and objective way for early prevention and…

图像与视频处理 · 电气工程与系统科学 2021-11-16 Xin Zhang , Liangxiu Han , Wenyong Zhu , Liang Sun , Daoqiang Zhang

Pattern recognition methods using neuroimaging data for the diagnosis of Alzheimer's disease have been the subject of extensive research in recent years. In this paper, we use deep learning methods, and in particular sparse autoencoders and…

计算机视觉与模式识别 · 计算机科学 2015-02-10 Adrien Payan , Giovanni Montana

This report provides an overview of the current state of the art deep learning architectures and optimisation techniques, and uses the ADNI hippocampus MRI dataset as an example to compare the effectiveness and efficiency of different…

机器学习 · 计算机科学 2015-05-11 Matthew Lai

Deep learning (DL) models have shown significant potential in Alzheimer's Disease (AD) classification. However, understanding and interpreting these models remains challenging, which hinders the adoption of these models in clinical…

计算机视觉与模式识别 · 计算机科学 2024-09-10 Thomas Yu Chow Tam , Litian Liang , Ke Chen , Haohan Wang , Wei Wu

Alzheimer's Disease destroys brain cells causing people to lose their memory, mental functions and ability to continue daily activities. It is a severe neurological brain disorder which is not curable, but earlier detection of Alzheimer's…

计算机视觉与模式识别 · 计算机科学 2017-12-21 Jyoti Islam , Yanqing Zhang

Alzheimer's Disease (AD) causes a continuous decline in memory, thinking, and judgment. Traditional diagnoses are usually based on clinical experience, which is limited by some realistic factors. In this paper, we focus on exploiting deep…

图像与视频处理 · 电气工程与系统科学 2023-03-14 Fangyu Zuo , Peiguang Jing , Jinglin Sun , Jizhong , Duan , Yong Ji , Yu Liu

Deep neural networks with rectified linear units (ReLU) are getting more and more popular due to their universal representation power and successful applications. Some theoretical progress regarding the approximation power of deep ReLU…

数值分析 · 数学 2020-02-28 Bo Li , Shanshan Tang , Haijun Yu

Over the past few years, there has been a significant amount of research focused on studying the ReLU activation function, with the aim of achieving neural network convergence through over-parametrization. However, recent developments in…

机器学习 · 计算机科学 2023-03-30 Yeqi Gao , Sridhar Mahadevan , Zhao Song

Doubly robust estimators are widely used for estimating average treatment effects and other linear summaries of regression functions. While consistency requires only one of two nuisance functions to be estimated consistently, asymptotic…

统计方法学 · 统计学 2025-07-01 Lars van der Laan , Alex Luedtke , Marco Carone

Over the past decade, machine learning techniques especially predictive modeling and pattern recognition in biomedical sciences from drug delivery system to medical imaging has become one of the important methods which are assisting…

计算机视觉与模式识别 · 计算机科学 2016-03-30 Saman Sarraf , Ghassem Tofighi

A plethora of deep learning models have been developed for the task of Alzheimer's disease classification from brain MRI scans. Many of these models report high performance, achieving three-class classification accuracy of up to 95%.…

计算机视觉与模式识别 · 计算机科学 2019-04-18 Ziqiang Guan , Ritesh Kumar , Yi Ren Fung , Yeahuay Wu , Madalina Fiterau

Delineating the associations between images and a vector of covariates is of central interest in medical imaging studies. To tackle this problem of image response regression, we propose a novel nonparametric approach in the framework of…

机器学习 · 统计学 2022-03-04 Daiwei Zhang , Lexin Li , Chandra Sripada , Jian Kang

Motivation. While recent studies show high accuracy in the classification of Alzheimer's disease using deep neural networks, the underlying learned concepts have not been investigated. Goals. To systematically identify changes in brain…

Recent studies have shown that the choice of activation function can significantly affect the performance of deep learning networks. However, the benefits of novel activation functions have been inconsistent and task dependent, and…

机器学习 · 计算机科学 2022-01-25 Garrett Bingham , Risto Miikkulainen

Existing supervised approaches didn't make use of the low-level features which are actually effective to this task. And another deficiency is that they didn't consider the relation between pixels, which means effective features are not…

计算机视觉与模式识别 · 计算机科学 2018-04-13 Boheng Zhang , Shenglei Huang , Shaohan Hu

Alzheimer's disease (AD) progresses from asymptomatic changes to clinical symptoms, emphasizing the importance of early detection for proper treatment. Functional magnetic resonance imaging (fMRI), particularly dynamic functional network…

计算工程、金融与科学 · 计算机科学 2024-08-02 Yuxiang Wei , Anees Abrol , James Lah , Deqiang Qiu , Vince D. Calhoun

Early detection is a crucial goal in the study of Alzheimer's Disease (AD). In this work, we describe several techniques to boost the performance of 3D deep convolutional neural networks (CNNs) trained to detect AD using structural brain…

图像与视频处理 · 电气工程与系统科学 2020-04-07 Sheng Liu , Chhavi Yadav , Carlos Fernandez-Granda , Narges Razavian

We study approximation and statistical learning properties of deep ReLU networks under structural assumptions that mitigate the curse of dimensionality. We prove minimax-optimal uniform approximation rates for $s$-H\"older smooth functions…

统计理论 · 数学 2026-02-06 Thomas Nagler , Sophie Langer

Nonparametric mean function regression with repeated measurements serves as a cornerstone for many statistical branches, such as longitudinal/panel/functional data analysis. In this work, we investigate this problem using fully connected…

统计理论 · 数学 2025-02-27 Shunxing Yan , Fang Yao , Hang Zhou