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Major depressive disorder (MDD) is one of the most common mental disorders, with significant impacts on many daily activities and quality of life. It stands as one of the most common mental disorders globally and ranks as the second leading…

计算机视觉与模式识别 · 计算机科学 2024-12-31 Nojod M. Alotaibi , Areej M. Alhothali , Manar S. Ali

Predicting the presence of major depressive disorder (MDD) using behavioural and cognitive signals is a highly non-trivial task. The heterogeneous clinical profile of MDD means that any given speech, facial expression and/or observed…

Functional magnetic resonance imaging (fMRI) has become one of the most common imaging modalities for brain function analysis. Recently, graph neural networks (GNN) have been adopted for fMRI analysis with superior performance.…

神经元与认知 · 定量生物学 2022-11-02 Yue Yu , Xuan Kan , Hejie Cui , Ran Xu , Yujia Zheng , Xiangchen Song , Yanqiao Zhu , Kun Zhang , Razieh Nabi , Ying Guo , Chao Zhang , Carl Yang

Major depressive disorder (MDD) is a prevalent mental disorder associated with complex neurobiological changes that cannot be fully captured using a single imaging modality. The use of multimodal magnetic resonance imaging (MRI) provides a…

计算机视觉与模式识别 · 计算机科学 2026-04-14 Nojod M. Alotaibi , Areej M. Alhothali

Most brain disorders are very heterogeneous in terms of their underlying biology and developing analysis methods to model such heterogeneity is a major challenge. A promising approach is to use probabilistic regression methods to estimate…

机器学习 · 统计学 2018-12-03 Seyed Mostafa Kia , Christian F. Beckmann , Andre F. Marquand

Identifying functional connectivity biomarkers of major depressive disorder (MDD) patients is essential to advance understanding of the disorder mechanisms and early intervention. However, due to the small sample size and the high dimension…

机器学习 · 计算机科学 2023-01-09 Shuai Liu , Xiao Guo , Shun Qi , Huaning Wang , Xiangyu Chang

Due to its causal semantics, Bayesian networks (BN) have been widely employed to discover the underlying data relationship in exploratory studies, such as brain research. Despite its success in modeling the probability distribution of…

计算机视觉与模式识别 · 计算机科学 2015-06-24 Luping Zhou , Lei Wang , Lingqiao Liu , Philip Ogunbona , Dinggang Shen

There is increasing interest in learning how human brain networks vary as a function of a continuous trait, but flexible and efficient procedures to accomplish this goal are limited. We develop a Bayesian semiparametric model, which…

统计方法学 · 统计学 2017-02-02 Lu Wang , Daniele Durante , Rex E. Jung , David B. Dunson

Brain connectivity analysis is crucial for understanding brain structure and neurological function, shedding light on the mechanisms of mental illness. To study the association between individual brain connectivity networks and the clinical…

In this study we focus on the problem of joint learning of multiple differential networks with function Magnetic Resonance Imaging (fMRI) data sets from multiple research centers. As the research centers may use different scanners and…

统计方法学 · 统计学 2021-06-08 Hao Chen , Ying Guo , Yong He , Dong Liu , Lei Liu , Xiao-Hua Zhou

Traditional causal connectivity methods in task-based and resting-state functional magnetic resonance imaging (fMRI) face challenges in accurately capturing directed information flow due to their sensitivity to noise and inability to model…

神经元与认知 · 定量生物学 2025-04-03 Boseong Kim , Debashis Das Chakladar , Haejun Chung , Ikbeom Jang

Patients with dementia typically exhibit cognitive impairment, which is routinely assessed using the Mini-Mental State Examination (MMSE). Concurrently, their underlying neurophysiological abnormalities are reflected in…

机器学习 · 计算机科学 2026-04-28 Xiaoyu Zheng , Xu Tian , Bin Jiao , Kunbo Cui , Hanhe Lin , Lu Shen , Jin Liu

Functional magnetic resonance imaging (fMRI) is one of the most common imaging modalities to investigate brain functions. Recent studies in neuroscience stress the great potential of functional brain networks constructed from fMRI data for…

机器学习 · 计算机科学 2022-05-31 Xuan Kan , Hejie Cui , Joshua Lukemire , Ying Guo , Carl Yang

On the increase of major depressive disorders (MDD), many researchers paid attention to their recognition and treatment. Existing MDD recognition algorithms always use a single time-frequency domain method method, but the single…

神经元与认知 · 定量生物学 2021-11-03 Xiaofang Sun , Xiangwei Zheng , Yonghui Xu , Lizhen Cui , Bin Hu

Despite the impressive advances achieved using deep learning for functional brain activity analysis, the heterogeneity of functional patterns and the scarcity of imaging data still pose challenges in tasks such as identifying neurological…

图像与视频处理 · 电气工程与系统科学 2025-05-30 Wenhui Cui , Haleh Akrami , Anand A. Joshi , Richard M. Leahy

Time Varying Functional Connectivity (TVFC) investigates how the interactions among brain regions vary over the course of an fMRI experiment. The transitions between different individual connectivity states can be modulated by changes in…

Repetitive Transcranial Magnetic Stimulation (rTMS) is a well-supported, evidence-based treatment for depression. However, patterns of response to this treatment are inconsistent. Emerging evidence suggests that artificial intelligence can…

Accurate brain tumor segmentation from multi-modal magnetic resonance imaging (MRI) is a prerequisite for precise radiotherapy planning and surgical navigation. While recent Transformer-based models such as Swin UNETR have achieved…

计算机视觉与模式识别 · 计算机科学 2026-01-27 Yan Zhou , Zhen Huang , Yingqiu Li , Yue Ouyang , Suncheng Xiang , Zehua Wang

Recently, there has been increased interest in fusing multimodal imaging to better understand brain organization. Specifically, accounting for knowledge of anatomical pathways connecting brain regions should lead to desirable outcomes such…

应用统计 · 统计学 2018-03-02 Ixavier A. Higgins , Suprateek Kundu , Ying Guo

Recent studies in neuroscience highlight the significant potential of brain connectivity networks, which are commonly constructed from functional magnetic resonance imaging (fMRI) data for brain disorder diagnosis. Traditional brain…

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