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More than 5 million children under five years die from largely preventable or treatable medical conditions every year, with an overwhelmingly large proportion of deaths occurring in underdeveloped countries with low vaccination uptake. One…

计算机与社会 · 计算机科学 2024-02-02 Opadele Kehinde , Ruth Abdul , Bose Afolabi , Parminder Vir , Corinne Namblard , Ayan Mukhopadhyay , Abiodun Adereni

Epidemic risk assessment poses inherent challenges, with traditional approaches often failing to balance health outcomes and economic constraints. This paper presents a data-driven decision support tool that models epidemiological dynamics…

应用统计 · 统计学 2025-11-24 Chang Zhai , Ping Chen , Zhuo Jin , David Pitt

Millions of young people are not immunized in low- and middle-income (LMI) countries because of low vaccine availability resulting from inefficiencies in cold supply chains. We create supply chain network design and distribution models to…

应用统计 · 统计学 2020-06-11 Zahra Azadi , Sandra D. Eksioglu , H. Neil Geismar

Immunization remains one of the most effective public health interventions, substantially reducing childhood morbidity and mortality worldwide. Yet, gender disparity and women's disempowerment continue to hinder access to vaccination…

Rural Bangladesh is confronted with substantial healthcare obstacles, such as inadequate infrastructure, inadequate information systems, and restricted access to medical personnel. These obstacles impede effective disease control and…

We study an optimal control problem where the objective is to find the best vaccine allocation during an epidemic outbreak. The epidemic dynamics is described by an age-structured SIR model with nonlocal interactions. Both the infection and…

最优化与控制 · 数学 2026-05-19 Luís Almeida , Romain Ducasse , Elisa Paparelli

As observed during the COVID-19 pandemic, high-income countries, such as the U.S., may exhibit vaccine nationalism during a pandemic: stockpiling doses of vaccine for their own citizens and being reluctant to distribute doses of the vaccine…

种群与进化 · 定量生物学 2024-08-21 Abraham Holleran , Susan E. Martonosi , Michael Veatch

Since early 2020, the world has been dealing with a raging pandemic outbreak: COVID-19. A year later, vaccines have become accessible, but in limited quantities, so that governments needed to devise a strategy to decide which part of the…

种群与进化 · 定量生物学 2022-04-13 Sander Tonkens , Paul de Klaver , Mauro Salazar

Vaccination has been proven to be the most effective method to prevent infectious diseases. However, there are still millions of children in low and middle-income countries who are not covered by routine vaccines and remain at risk. The…

物理与社会 · 物理学 2021-04-30 Yuwen Yang , Hoda Bidkhori , Jayant Rajgopal

To mitigate the impact of the pandemic, several measures include lockdowns, rapid vaccination programs, school closures, and economic stimulus. These interventions can have positive or unintended negative consequences. Current research to…

机器学习 · 计算机科学 2025-08-11 Gaurav Deshkar , Jayanta Kshirsagar , Harshal Hayatnagarkar , Janani Venugopalan

During the Covid-19 pandemic a key role is played by vaccination to combat the virus. There are many possible policies for prioritizing vaccines, and different criteria for optimization: minimize death, time to herd immunity, functioning of…

AI tools increasingly guide targeted interventions in healthcare, education, and recruiting. Algorithms score individuals, trigger outreach to those above a threshold (e.g., high-risk or high-value), and encourage them to request service;…

统计方法学 · 统计学 2026-04-17 Carri W. Chan , Yi Han , Hannah Li , Benjamin L. Ranard

Network-based interventions against epidemic spread are most powerful when the full network structure is known. However, in practice, resource constraints require decisions to be made based on partial network information. We investigated…

应用统计 · 统计学 2019-03-19 Yingrui Yang , Ashley McKhann , Sixing Chen , Guy Harling , Jukka-Pekka Onnela

An insufficient supply of effective SARS-CoV-2 vaccine in most countries demands an effective vaccination strategy to minimize the damage caused by the disease. Currently, many countries vaccinate their population in descending order of age…

物理与社会 · 物理学 2022-09-28 Bukyoung Jhun , Hoyun Choi

India accounts for 11% of maternal deaths globally where a woman dies in childbirth every fifteen minutes. Lack of access to preventive care information is a significant problem contributing to high maternal morbidity and mortality numbers,…

Background: Network-based interventions are most powerful against epidemics when the full network structure is known. However, resource constraints often require decisions based on partial network data. We investigated how the effectiveness…

种群与进化 · 定量生物学 2018-03-30 Yingrui Yang , Ashley McKhann , Guy Harling , Jukka-Pekka Onnela

Effective vaccine prioritization is critical for epidemic control, yet real outbreaks exhibit memory effects that inflate state space and make long-term prediction and optimization challenging. As a result, many strategies are tuned to…

生物物理 · 物理学 2025-11-11 Mi Feng , Liang Tian , Changsong Zhou

Controlling and understanding epidemic outbreaks has recently drawn great interest in a large spectrum of research communities. Vaccination is one of the most well-established and effective strategies in order to contain an epidemic. In the…

社会与信息网络 · 计算机科学 2023-05-29 Sourin Chatterjee , Ahad N. Zehmakan

The COVID-19 pandemic has so far accounted for reported 5.5M deaths worldwide, with 8.7% of these coming from India. The pandemic exacerbated the weakness of the Indian healthcare system. As of January 20, 2022, India is the second worst…

计算机与社会 · 计算机科学 2022-06-07 Tanvi Karandikar , Avinash Prabhu , Mehul Mathur , Megha Arora , Hemank Lamba , Ponnurangam Kumaraguru

Vaccinations are an important tool in the prevention of disease. Vaccinations are generally voluntary for each member of a population and vaccination decisions are influenced by individual risk perceptions and contact structures within…

物理与社会 · 物理学 2025-04-07 Kausutua Tjikundi , Mark Broom
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