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Colorectal liver metastases (CLM) significantly impact colon cancer patients, influencing survival based on systemic chemotherapy response. Traditional methods like tumor grading scores (e.g., tumor regression grade - TRG) for prognosis…

Microscopic examination of tissues or histopathology is one of the diagnostic procedures for detecting colorectal cancer. The pathologist involved in such an examination usually identifies tissue type based on texture analysis, especially…

图像与视频处理 · 电气工程与系统科学 2020-04-06 Srinath Jayachandran , Ashlin Ghosh

Nasopharyngeal Carcinoma (NPC) is a malignant epithelial cancer arising from the nasopharynx. Survival prediction is a major concern for NPC patients, as it provides early prognostic information to plan treatments. Recently, deep survival…

图像与视频处理 · 电气工程与系统科学 2022-09-20 Mingyuan Meng , Bingxin Gu , Lei Bi , Shaoli Song , David Dagan Feng , Jinman Kim

This study focuses on automatic skin cancer detection using a Meta-learning approach for dermoscopic images. The aim of this study is to explore the benefits of the generalization of the knowledge extracted from non-medical data in the…

计算机视觉与模式识别 · 计算机科学 2021-04-23 Sara I. Garcia

Breast cancer is the second most common type of cancer in women in Canada and the United States, representing over 25\% of all new female cancer cases. As such, there has been immense research and progress on improving screening and…

计算机视觉与模式识别 · 计算机科学 2023-08-07 Chi-en Amy Tai , Hayden Gunraj , Nedim Hodzic , Nic Flanagan , Ali Sabri , Alexander Wong

In many histopathology tasks, sample classification depends on morphological details in tissue or single cells that are only visible at the highest magnification. For a pathologist, this implies tedious zooming in and out, while for a…

计算机视觉与模式识别 · 计算机科学 2023-03-03 Ario Sadafi , Nassir Navab , Carsten Marr

Purpose: To determine whether deep learning models can distinguish between breast cancer molecular subtypes based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). Materials and methods: In this institutional review…

计算机视觉与模式识别 · 计算机科学 2017-12-01 Zhe Zhu , Ehab Albadawy , Ashirbani Saha , Jun Zhang , Michael R. Harowicz , Maciej A. Mazurowski

Deep learning methods such as convolutional neural networks (CNNs) are difficult to directly utilize to analyze whole slide images (WSIs) due to the large image dimensions. We overcome this limitation by proposing a novel two-stage…

图像与视频处理 · 电气工程与系统科学 2021-06-15 Shivam Kalra , Mohammed Adnan , Sobhan Hemati , Taher Dehkharghanian , Shahryar Rahnamayan , Hamid Tizhoosh

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

定量方法 · 定量生物学 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

Survival prediction models can potentially be used to guide treatment of glioblastoma patients. However, currently available MR imaging biomarkers holding prognostic information are often challenging to interpret, have difficulties…

图像与视频处理 · 电气工程与系统科学 2021-09-28 Sveinn Pálsson , Stefano Cerri , Hans Skovgaard Poulsen , Thomas Urup , Ian Law , Koen Van Leemput

In the field of computational pathology, the use of decision support systems powered by state-of-the-art deep learning solutions has been hampered by the lack of large labeled datasets. Until recently, studies relied on datasets in the…

计算机视觉与模式识别 · 计算机科学 2018-10-01 Gabriele Campanella , Vitor Werneck Krauss Silva , Thomas J. Fuchs

Survival prediction for cancer patients is critical for optimal treatment selection and patient management. Current patient survival prediction methods typically extract survival information from patients' clinical record data or biological…

图像与视频处理 · 电气工程与系统科学 2024-07-26 Amr Hagag , Ahmed Gomaa , Dominik Kornek , Andreas Maier , Rainer Fietkau , Christoph Bert , Florian Putz , Yixing Huang

Colorectal diseases, including inflammatory conditions and neoplasms, require quick, accurate care to be effectively treated. Traditional diagnostic pipelines require extensive preparation and rely on separate, individual evaluations on…

计算机视觉与模式识别 · 计算机科学 2025-09-09 Krithik Ramesh , Ritvik Koneru

In recent years, the integration of pre-trained foundational models with multiple instance learning (MIL) has improved diagnostic accuracy in computational pathology. However, existing MIL methods focus on optimizing feature extractors and…

计算机视觉与模式识别 · 计算机科学 2025-12-24 Le Feng , Li Xiao

In this study, an automated three dimensional (3D) deep segmentation approach for detecting gliomas in 3D pre-operative MRI scans is proposed. Then, a classi-fication algorithm based on random forests, for survival prediction is presented.…

图像与视频处理 · 电气工程与系统科学 2019-11-20 Mehdi Amian , Mohammadreza Soltaninejad

Gastric diffuse-type adenocarcinoma represents a disproportionately high percentage of cases of gastric cancers occurring in the young, and its relative incidence seems to be on the rise. Usually it affects the body of the stomach, and…

图像与视频处理 · 电气工程与系统科学 2021-04-27 Fahdi Kanavati , Masayuki Tsuneki

Survival prediction is crucial for cancer patients as it provides early prognostic information for treatment planning. Recently, deep survival models based on deep learning and medical images have shown promising performance for survival…

图像与视频处理 · 电气工程与系统科学 2023-10-03 Mingyuan Meng , Lei Bi , Michael Fulham , Dagan Feng , Jinman Kim

Breast-conserving surgery (BCS) aims to completely remove malignant lesions while maximizing healthy tissue preservation. Intraoperative margin assessment is essential to achieve a balance between thorough cancer resection and tissue…

图像与视频处理 · 电气工程与系统科学 2026-01-16 Pouya Afshin , David Helminiak , Tongtong Lu , Tina Yen , Julie M. Jorns , Mollie Patton , Bing Yu , Dong Hye Ye

Accurate and fast assessment of resection margins is an essential part of a dermatopathologist's clinical routine. In this work, we successfully develop a deep learning method to assist the pathologists by marking critical regions that have…

Whole-slide image (WSI) classification in computational pathology is commonly formulated as slide-level Multiple Instance Learning (MIL) with a single global bag representation. However, slide-level MIL is fundamentally underconstrained:…