相关论文: Mapping cell cortex rheology to tissue rheology, a…
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, although a comprehensive theory of biological pattern formation is still lacking. Here, we propose a minimal model combining tissue mechanics…
Colloidal dispersions are commonly encountered in everyday life and represent an important class of complex fluid. Of particular significance for many commercial products and industrial processes is the ability to control and manipulate the…
We probe the rheology of weakly vibrated granular flows as function of flow rate, vibration strength and pressure by performing experiments in a vertically vibrated split-bottom shear cell. For slow flows, we establish the existence of a…
The rheology of dense sheared granular liquids is investigated based on the mode-coupling theory (MCT). This extended MCT includes correlations for the density-current mode as well as the density-density correlation mode, and a…
Organogenesis involves large deformations and complex shape changes that require elaborate mechanical regulation. Models of tissue biomechanics have been introduced to account for the coupling between mechanical response and biochemical…
The viscosity of fluids is generally understood in terms of kinetic mechanisms, i.e., particle collisions, or thermodynamic ones as imposed through structural distortions upon e.g. applying shear. Often the former is less relevant, and…
We study a model of contraction-based cell motility inside a microchannel to investigate the regulation of cell polarization and motion by the mechanical resistance of the environment. A positive feedback between the asymmetry of the…
A continuum model of epithelial tissue mechanics was formulated using cellular-level mechanical ingredients and cell morphogenetic processes, including cellular shape changes and cellular rearrangements. This model can include finite…
We propose a simple micro-rheology technique to evaluate the viscoelastic properties of complex fluids. The method is based on the use of magnetic wires of a few microns in length submitted to a rotational magnetic field. In this work, the…
In recent years, significant effort has been devoted to developing smart materials whose mechanical properties can adapt under physical stimuli. Particulate colloidal gels, which behave as solids but can also flow under stress, have emerged…
The reconstruction of cortical surfaces from brain magnetic resonance imaging (MRI) scans is essential for quantitative analyses of cortical thickness and sulcal morphology. Although traditional and deep learning-based algorithmic pipelines…
Various structures in human physiology follow a treelike morphology, which often expresses complexity at very fine scales. Examples of such structures are intrathoracic airways, retinal blood vessels, and hepatic blood vessels. Large…
State of the art research and treatment of biological tissues require accurate and efficient methods for describing their mechanical properties. Indeed, micromechanics motivated approaches provide a systematic method for elevating relevant…
Soft cellular systems, such as foams or biological tissues, exhibit highly complex rheological properties, even in the quasistatic regime, that numerical modeling can help to apprehend. We present a numerical implementation of quasistatic…
Skeletal muscle is subjected to simultaneous time-varying neural stimuli and length changes in vivo. Work loops are experimental representations of these in vivo conditions and exhibit force versus length responses that are not explainable…
During growth, tissue expands and deforms. Given its elastic properties, stresses emerge in an expanding and deforming tissue. Cell rearrangements can dissipate these stresses and numerous experiments confirm the viscoelastic properties of…
The goal of this work is to investigate under which circumstances the tidal response of a stratified body can be approximated by that of a homogeneous body. We show that any multilayered planet model can be approximated by a homogeneous…
In cell extrusion, a cell embedded in an epithelial monolayer loses its apical or basal surface and is subsequently squeezed out of the monolayer by neighboring cells. Cell extrusions occur during apoptosis, epithelial-mesenchymal…
In situ interfacial rheology and numerical simulations are used to investigate microgel monolayers in a wide range of packing fractions, $\zeta_{2D}$. The heterogeneous particle compressibility determines two flow regimes characterized by…
Power law rheology is of widespread occurrence in complex materials that are characterized by the presence of a very broad range of microstructural length and time scales. Although phenomenological models able to reproduce the observed…