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We address the problem of predicting when a disease will develop, i.e., medical event time (MET), from a patient's electronic health record (EHR). The MET of non-communicable diseases like diabetes is highly correlated to cumulative health…

机器学习 · 计算机科学 2023-06-01 Takayuki Katsuki , Kohei Miyaguchi , Akira Koseki , Toshiya Iwamori , Ryosuke Yanagiya , Atsushi Suzuki

The advent of large language models (LLMs) has opened new avenues for analyzing complex, unstructured data, particularly within the medical domain. Electronic Health Records (EHRs) contain a wealth of information in various formats,…

信息检索 · 计算机科学 2025-06-10 Wu Hao Ran , Xi Xi , Furong Li , Jingyi Lu , Jian Jiang , Hui Huang , Yuzhuan Zhang , Shi Li

We develop a prediction-based prescriptive model for learning optimal personalized treatments for patients based on their Electronic Health Records (EHRs). Our approach consists of: (i) predicting future outcomes under each possible therapy…

机器学习 · 统计学 2018-12-06 Ruidi Chen , Ioannis Paschalidis

Patient representation learning refers to learning a dense mathematical representation of a patient that encodes meaningful information from Electronic Health Records (EHRs). This is generally performed using advanced deep learning methods.…

机器学习 · 计算机科学 2021-01-26 Yuqi Si , Jingcheng Du , Zhao Li , Xiaoqian Jiang , Timothy Miller , Fei Wang , W. Jim Zheng , Kirk Roberts

Electronic Health Records (EHRs) are rich sources of patient-level data, offering valuable resources for medical data analysis. However, privacy concerns often restrict access to EHRs, hindering downstream analysis. Current EHR…

机器学习 · 计算机科学 2024-12-03 Muhang Tian , Bernie Chen , Allan Guo , Shiyi Jiang , Anru R. Zhang

Electronic health records (EHR) are widely used to study clinical decisions, yet unmeasured confounding remains a persistent challenge. Proxy variables offer a potential solution. In EHR data, clinicians already record many such…

统计方法学 · 统计学 2026-03-23 Haley Colgate Kottler , Amy Cochran

Electronic Health Records (EHR) are high-dimensional data with implicit connections among thousands of medical concepts. These connections, for instance, the co-occurrence of diseases and lab-disease correlations can be informative when…

机器学习 · 计算机科学 2021-03-29 Weicheng Zhu , Narges Razavian

The widespread adoption of electronic health records (EHRs) enables the acquisition of heterogeneous clinical data, spanning lab tests, vital signs, medications, and procedures, which offer transformative potential for artificial…

信号处理 · 电气工程与系统科学 2026-03-17 Mingcheng Zhu , Yu Liu , Zhiyao Luo , Tingting Zhu

This paper addresses patient heterogeneity associated with prediction problems in biomedical applications. We propose a systematic hypothesis testing approach to determine the existence of patient subgroup structure and the number of…

统计方法学 · 统计学 2021-01-08 Xu Gao , Weining Shen , Jing Ning , Ziding Feng , Jianhua Hu

The rapid accumulation of Electronic Health Records (EHRs) has transformed healthcare by providing valuable data that enhance clinical predictions and diagnoses. While conventional machine learning models have proven effective, they often…

Extracting actionable insight from Electronic Health Records (EHRs) poses several challenges for traditional machine learning approaches. Patients are often missing data relative to each other; the data comes in a variety of modalities,…

机器学习 · 计算机科学 2018-11-13 Brandon Malone , Alberto Garcia-Duran , Mathias Niepert

Employing a machine learning approach we predict, up to 24 hours prior, a diagnosis of severe sepsis. Strongly predictive models are possible that use only text reports from the Electronic Health Record (EHR), and omit structured numerical…

计算机与社会 · 计算机科学 2017-12-01 Phil Culliton , Michael Levinson , Alice Ehresman , Joshua Wherry , Jay S. Steingrub , Stephen I. Gallant

Learning electronic health records (EHRs) has received emerging attention because of its capability to facilitate accurate medical diagnosis. Since the EHRs contain enriched information specifying complex interactions between entities,…

机器学习 · 计算机科学 2024-08-15 Tsai Hor Chan , Guosheng Yin , Kyongtae Bae , Lequan Yu

Predicting disease trajectories from electronic health records (EHRs) is a complex task due to major challenges such as data non-stationarity, high granularity of medical codes, and integration of multimodal data. EHRs contain both…

机器学习 · 计算机科学 2025-02-26 Sifal Klioui , Sana Sellami , Youssef Trardi

Accurate and explainable health event predictions are becoming crucial for healthcare providers to develop care plans for patients. The availability of electronic health records (EHR) has enabled machine learning advances in providing these…

机器学习 · 计算机科学 2021-05-18 Chang Lu , Chandan K. Reddy , Prithwish Chakraborty , Samantha Kleinberg , Yue Ning

We introduce HTAD, a novel model for diagnosis prediction using Electronic Health Records (EHR) represented as Heterogeneous Information Networks. Recent studies on modeling EHR have shown success in automatically learning representations…

机器学习 · 计算机科学 2019-12-24 Anahita Hosseini , Tyler Davis , Majid Sarrafzadeh

Despite the abundance of Electronic Healthcare Records (EHR), its heterogeneity restricts the utilization of medical data in building predictive models. To address this challenge, we propose Universal Healthcare Predictive Framework…

机器学习 · 计算机科学 2024-09-04 Kyunghoon Hur , Jungwoo Oh , Junu Kim , Jiyoun Kim , Min Jae Lee , Eunbyeol Cho , Seong-Eun Moon , Young-Hak Kim , Edward Choi

Predicting health risks from electronic health records (EHR) is a topic of recent interest. Deep learning models have achieved success by modeling temporal and feature interaction. However, these methods learn insufficient representations…

机器学习 · 计算机科学 2023-12-19 Zhihao Yu , Chaohe Zhang , Yasha Wang , Wen Tang , Jiangtao Wang , Liantao Ma

Electronic health records represent a holistic overview of patients' trajectories. Their increasing availability has fueled new hopes to leverage them and develop accurate risk prediction models for a wide range of diseases. Given the…

With the widespread of machine learning models for healthcare applications, there is increased interest in building applications for personalized medicine. Despite the plethora of proposed research for personalized medicine, very few focus…

机器学习 · 计算机科学 2024-02-27 Ghadeer O. Ghosheh , Jin Li , Tingting Zhu