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We focus on tertiary lymphoid structure (TLS) semantic segmentation in whole slide image (WSI). Unlike TLS binary segmentation, TLS semantic segmentation identifies boundaries and maturity, which requires integrating contextual information…

计算机视觉与模式识别 · 计算机科学 2024-12-10 Lei Su , Yang Du

Convolutional neural networks (CNNs) for biomedical image analysis are often of very large size, resulting in high memory requirement and high latency of operations. Searching for an acceptable compressed representation of the base CNN for…

计算机视觉与模式识别 · 计算机科学 2019-09-10 Suraj Mishra , Peixian Liang , Adam Czajka , Danny Z. Chen , X. Sharon Hu

Pretraining on large-scale, in-domain datasets grants histopathology foundation models (FM) the ability to learn task-agnostic data representations, enhancing transfer learning on downstream tasks. In computational pathology, automated…

计算机视觉与模式识别 · 计算机科学 2025-07-22 Pablo Meseguer , Rocío del Amor , Valery Naranjo

Analyzing high resolution whole slide images (WSIs) with regard to information across multiple scales poses a significant challenge in digital pathology. Multi-instance learning (MIL) is a common solution for working with high resolution…

Accurate lung lesion segmentation from Computed Tomography (CT) images is crucial to the analysis and diagnosis of lung diseases such as COVID-19 and lung cancer. However, the smallness and variety of lung nodules and the lack of…

图像与视频处理 · 电气工程与系统科学 2022-04-15 Changwei Wang , Rongtao Xu , Shibiao Xu , Weiliang Meng , Jun Xiao , Xiaopeng Zhang

Histopathology whole slide images (WSIs) play a very important role in clinical studies and serve as the gold standard for many cancer diagnoses. However, generating automatic tools for processing WSIs is challenging due to their enormous…

计算机视觉与模式识别 · 计算机科学 2022-09-28 Jingwei Zhang , Xin Zhang , Ke Ma , Rajarsi Gupta , Joel Saltz , Maria Vakalopoulou , Dimitris Samaras

Longitudinal MRI analysis is crucial for predicting disease outcomes, particularly in chronic conditions like hepatocellular carcinoma (HCC), where early detection can significantly influence treatment strategies and patient prognosis. Yet,…

计算机视觉与模式识别 · 计算机科学 2025-01-23 Jakob Nolte , Maureen M. J. Guichelaar , Donald E. Bouman , Stephanie M. van den Berg , Maryam Amir Haeri

Hyperspectral image (HSI) classification is challenging due to spatial variability caused by complex imaging conditions. Prior methods suffer from limited representation ability, as they train specially designed networks from scratch on…

计算机视觉与模式识别 · 计算机科学 2023-05-17 Di Wang , Jing Zhang , Bo Du , Liangpei Zhang , Dacheng Tao

Multiple Instance Learning (MIL) represents the predominant framework in Whole Slide Image (WSI) classification, covering aspects such as sub-typing, diagnosis, and beyond. Current MIL models predominantly rely on instance-level features…

计算机视觉与模式识别 · 计算机科学 2024-07-26 Heng Fang , Sheng Huang , Wenhao Tang , Luwen Huangfu , Bo Liu

Accurate survival prediction from histopathology whole-slide images (WSIs) remains challenging due to their gigapixel resolution, strong spatial heterogeneity, and complex survival distributions. We introduce a comprehensive computational…

计算机视觉与模式识别 · 计算机科学 2025-11-18 Ardhendu Sekhar , Vasu Soni , Keshav Aske , Shivam Madnoorkar , Pranav Jeevan , Amit Sethi

Multiple Instance Learning (MIL) and transformers are increasingly popular in histopathology Whole Slide Image (WSI) classification. However, unlike human pathologists who selectively observe specific regions of histopathology tissues under…

计算机视觉与模式识别 · 计算机科学 2023-07-18 Conghao Xiong , Hao Chen , Joseph J. Y. Sung , Irwin King

Survival prediction is a complex ordinal regression task that aims to predict the survival coefficient ranking among a cohort of patients, typically achieved by analyzing patients' whole slide images. Existing deep learning approaches…

计算机视觉与模式识别 · 计算机科学 2024-05-01 Minghao Han , Xukun Zhang , Dingkang Yang , Tao Liu , Haopeng Kuang , Jinghui Feng , Lihua Zhang

Whole Slide Images (WSIs) exhibit hierarchical structure, where diagnostic information emerges from cellular morphology, regional tissue organization, and global context. Existing Computational Pathology (CPath) Multimodal Large Language…

Hyperspectral image (HSI) denoising is an essential procedure for HSI applications. Unfortunately, the existing Transformer-based methods mainly focus on non-local modeling, neglecting the importance of locality in image denoising.…

图像与视频处理 · 电气工程与系统科学 2024-08-05 Hao Liang , Chengjie , Kun Li , Xin Tian

Deep neural networks (DNNs) have exhibited remarkable success in the field of histopathology image analysis. On the other hand, the contemporary trend of employing large models and extensive datasets has underscored the significance of…

计算机视觉与模式识别 · 计算机科学 2024-08-20 Cong Cong , Shiyu Xuan , Sidong Liu , Maurice Pagnucco , Shiliang Zhang , Yang Song

Developing deep learning models to analyze histology images has been computationally challenging, as the massive size of the images causes excessive strain on all parts of the computing pipeline. This paper proposes a novel deep…

图像与视频处理 · 电气工程与系统科学 2021-01-13 Joseph DiPalma , Arief A. Suriawinata , Laura J. Tafe , Lorenzo Torresani , Saeed Hassanpour

Deep learning has proven to be more effective than other methods in medical image analysis, including the seemingly simple but challenging task of segmenting individual cells, an essential step for many biological studies. Comparative…

图像与视频处理 · 电气工程与系统科学 2023-11-07 Valentina Vadori , Antonella Peruffo , Jean-Marie Graïc , Livio Finos , Livio Corain , Enrico Grisan

The problem of recognizing various types of tissues present in multi-gigapixel histology images is an important fundamental pre-requisite for downstream analysis of the tumor microenvironment in a bottom-up analysis paradigm for…

图像与视频处理 · 电气工程与系统科学 2021-04-02 Nima Hatami , Mohsin Bilal , Nasir Rajpoot

Digital gigapixel whole slide image (WSI) is widely used in clinical diagnosis, and automated WSI analysis is key for computer-aided diagnosis. Currently, analyzing the integrated descriptor of probabilities or feature maps from massive…

计算机视觉与模式识别 · 计算机科学 2022-06-06 Ziquan Wei , Shenghua Cheng , Junbo Hu , Li Chen , Shaoqun Zeng , Xiuli Liu

Pathology slides of lung malignancies are classified using resource-frugal convolution neural networks (CNNs) that may be deployed on mobile devices. In particular, the challenging task of distinguishing adenocarcinoma (LUAD) and…

图像与视频处理 · 电气工程与系统科学 2021-03-26 Steven J. Frank