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Lung cancer is the leading cause of patient mortality in the world. Early diagnosis of malignant pulmonary nodules in CT images can have a significant impact on reducing disease mortality and morbidity. In this work, we propose LMLCC-Net, a…

图像与视频处理 · 电气工程与系统科学 2025-11-27 Tasnia Binte Mamun , Adhora Madhuri , Nusaiba Sobir , Taufiq Hasan

Multimodal learning that integrates histopathology images and genomic data holds great promise for cancer survival prediction. However, existing methods face key limitations: 1) They rely on multimodal mapping and metrics in Euclidean…

计算机视觉与模式识别 · 计算机科学 2025-03-19 Jiaqi Yang , Wenting Chen , Xiaohan Xing , Sean He , Xiaoling Luo , Xinheng Lyu , Linlin Shen , Guoping Qiu

Histopathology whole slide images (WSIs) are being widely used to develop deep learning-based diagnostic solutions, especially for precision oncology. Most of these diagnostic softwares are vulnerable to biases and impurities in the…

图像与视频处理 · 电气工程与系统科学 2024-10-01 Abhijeet Patil , Harsh Diwakar , Jay Sawant , Nikhil Cherian Kurian , Subhash Yadav , Swapnil Rane , Tripti Bameta , Amit Sethi

Whole-Slide Image (WSI) is an important tool for estimating cancer prognosis. Current studies generally follow a conventional cancer-specific paradigm in which each cancer corresponds to a single model. However, this paradigm naturally…

图像与视频处理 · 电气工程与系统科学 2025-12-03 Pei Liu , Luping Ji , Jiaxiang Gou , Xiangxiang Zeng

Controlling false positives (Type I errors) through statistical hypothesis testing is a foundation of modern scientific data analysis. Existing causal structure discovery algorithms either do not provide Type I error control or cannot scale…

统计方法学 · 统计学 2025-12-29 James Leiner , Brian Manzo , Aaditya Ramdas , Wesley Tansey

The boundary of tumors (hepatocellular carcinoma, or HCC) contains rich semantics: capsular invasion, visibility, smoothness, folding and protuberance, etc. Capsular invasion on tumor boundary has proven to be clinically correlated with the…

计算机视觉与模式识别 · 计算机科学 2021-03-10 Jieneng Chen , Ke Yan , Yu-Dong Zhang , Youbao Tang , Xun Xu , Shuwen Sun , Qiuping Liu , Lingyun Huang , Jing Xiao , Alan L. Yuille , Ya Zhang , Le Lu

Gene mutation prediction in hepatocellular carcinoma (HCC) is of great diagnostic and prognostic value for personalized treatments and precision medicine. In this paper, we tackle this problem with multi-instance multi-label learning to…

机器学习 · 计算机科学 2022-03-24 Kaixin Xu , Ziyuan Zhao , Jiapan Gu , Zeng Zeng , Chan Wan Ying , Lim Kheng Choon , Thng Choon Hua , Pierce KH Chow

Recent studies have made significant progress in developing large language models (LLMs) in the medical domain, which can answer expert-level questions and demonstrate the potential to assist clinicians in real-world clinical scenarios.…

计算与语言 · 计算机科学 2025-04-18 Sangwook Kim , Soonyoung Lee , Jongseong Jang

Thyroid carcinoma, a significant yet often controllable cancer, has seen a rise in cases, largely due to advancements in diagnostic methods. Differentiated thyroid cancer (DTC), which includes papillary and follicular varieties, is…

机器学习 · 计算机科学 2025-05-06 Mohammad Al-Sayed Ahmad , Jude Haddad

Self-supervised learning (SSL) has recently shown tremendous potential to learn generic visual representations useful for many image analysis tasks. Despite their notable success, the existing SSL methods fail to generalize to downstream…

计算机视觉与模式识别 · 计算机科学 2021-10-07 Chetan L Srinidhi , Anne L Martel

Lung cancer remains one of the leading causes of cancer-related mortality, yet most survival models rely only on baseline factors and overlook posttreatment variables that reflect disease progression. To address this gap, we applied Cox…

应用统计 · 统计学 2025-10-03 Varun Vishwanathan Nair , Victor Miranda Soberanis

Objectives: Approximately 30% of non-metastatic anal squamous cell carcinoma (ASCC) patients will experience recurrence after chemoradiotherapy (CRT), and currently available clinical variables are poor predictors of treatment response. We…

计算机视觉与模式识别 · 计算机科学 2023-09-07 Shanshan Tang , Kai Wang , David Hein , Gloria Lin , Nina N. Sanford , Jing Wang

Correct treatment of urothelial carcinoma patients is dependent on accurate grading and staging of the cancer tumour. This is determined manually by a pathologist by examining the histological whole-slide images (WSI). The large size of…

图像与视频处理 · 电气工程与系统科学 2019-09-12 Rune Wetteland , Kjersti Engan , Trygve Eftestøl , Vebjørn Kvikstad , Emilius A. M. Janssen

Melanoma represents a critical health risk due to its aggressive progression and high mortality, underscoring the need for early, interpretable diagnostic tools. While deep learning has advanced in skin lesion classification, most existing…

计算机视觉与模式识别 · 计算机科学 2025-07-28 Ciro Listone , Aniello Murano

Attention-based multiple instance learning (AMIL) algorithms have proven to be successful in utilizing gigapixel whole-slide images (WSIs) for a variety of different computational pathology tasks such as outcome prediction and cancer…

Radiation encephalopathy (REP) is the most common complication for nasopharyngeal carcinoma (NPC) radiotherapy. It is highly desirable to assist clinicians in optimizing the NPC radiotherapy regimen to reduce radiotherapy-induced temporal…

图像与视频处理 · 电气工程与系统科学 2022-06-24 Jiansheng Fang , Anwei Li , Pu-Yun OuYang , Jiajian Li , Jingwen Wang , Hongbo Liu , Fang-Yun Xie , Jiang Liu

In the present study, we propose a novel case-based similar image retrieval (SIR) method for hematoxylin and eosin (H&E)-stained histopathological images of malignant lymphoma. When a whole slide image (WSI) is used as an input query, it is…

Hepatocellular carcinoma is the most spread primary liver cancer across the world ($\sim$80\% of the liver tumors). The gold standard for HCC diagnosis is liver biopsy. However, in the clinical routine, expert radiologists provide a visual…

计算机视觉与模式识别 · 计算机科学 2025-01-15 E. Sarfati , A. Bône , M-M. Rohé , C. Aubé , M. Ronot , P. Gori , I. Bloch

We propose a novel continual self-supervised learning (CSSL) framework for simultaneously learning diverse features from multi-window-obtained chest computed tomography (CT) images and ensuring data privacy. Achieving a robust and highly…

Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer-related mortality worldwide, demands urgent improvements in early detection to enhance patient survival. While ultrasound remains the preferred screening modality…

计算机视觉与模式识别 · 计算机科学 2025-03-21 Chaoyin She , Ruifang Lu , Danni He , Jiayi Lv , Yadan Lin , Meiqing Cheng , Hui Huang , Fengyu Ye , Lida Chen , Wei Wang , Qinghua Huang
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